Hepatocyte spheroids underlayered with nonparenchymal cells for biomedical applications

IEICE Transactions on Electronics

Volumn E94-C, Issue 2, 2011, Pages 176-180

  NAkasone, Yuichi ^a   Yamamoto, Masashi ^a   Tateishi, Tetsuya ^a   Otsuka, Hidenori ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

3D culture; Hepatocyte; Micropatterning; PEGylation; Spheroid

Indexed keywords

CELLS; CYTOLOGY; ENDOTHELIAL CELLS; MEDICAL APPLICATIONS; PHYSIOLOGICAL MODELS; POLYETHYLENE GLYCOLS; SUBSTRATES;

3-D CULTURES; HEPATOCYTES; MICRO PATTERNING; PEGYLATION; SPHEROID;

CELL ENGINEERING;

EID: 79951496243     PISSN: 09168524     EISSN: 17451353     Source Type: Journal    
DOI: 10.1587/transele.E94.C.176     Document Type: Article

References (22)

1. J. Kononen, L. Bubendorf, A. Kallioniemi, M. Barlund, P. Schraml, S. Leighton, J. Torhorst, M.J. Mihatsch, G. Sauter, and O.P. Kallioniemi, "Tissue microarrays," Nat. Med., vol.4, pp.844-847, 1998.
2. S. Britland, P. Clark, P. Connolly, and G. Moores, "Micropatterned substrateum adhesiveness: A model for morphogenetic cues controlling cell behavior," Ex Cell Res., vol.198, pp.124-129, 1992.
3. H. Thielecke, A. Mack, and A. Robitzki, "A multicellular spheroidbased sensor for anti-canser therapeutics," Biosen. Bioelect., vol.16, pp.261-269, 2001. (Pubitemid 32522785)
4. A.R. Mack, H. Thielecke, and A.A. Robitzki, "3D-biohybrid systems: application in drug screening," Trends Biotechnol., vol.20, pp.56-61, 2002. (Pubitemid 34113941)
5. T. Shimizu, M. Yamato, A. Kikuchi, and T. Okano, "Cell sheet engineering for myocardial tissue reconstruction," Biomaterials, vol.24, pp.2309-2316, 2003. (Pubitemid 36434050)
6. V.L. Tsang and S.N. Bhatia, "Tree-dimensional tissue engineering," Adv. Drug Deliv. Rev., vol.56, pp.1635-1647, 2004.
7. J. Fukuda, H.Mizumoto, K. Nakazawa, T. Kajiwara, and K. Funatsu, "Hepatocyte organoid culture in elliptic hollow fibers to develop a hybrid artificial liver," Int. J. Artif. Organs, vol.27, pp.1091-1099, 2004.
8. S.N. Bhatia, U.J. Balis, M.L. Yarmush, and M. Toner, "Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells," FASEB J., vol.13, pp.1883-1900, 1999. (Pubitemid 29517619)
9. E.S. Tzanakakis, L.K. Hansen, and W.S. Hu, "The role of actin filaments and microtubules in hepatocyte spheroid self-assembly," Cell Motil. Cytoskele., vol.48, pp.175-189, 2001. (Pubitemid 32181928)
10. A. Folch and M. Toner, "Microengineering of cellular interactions," Annu. Rev. Biomed. Eng., vol.2, pp.227-256, 2000.
11. S.N. Bhatia, M.L. Yarmush, and M. Toner, "Controlling cell interactions by micropatterning in co-cultures: Hpetocytes and 3T3 fibroblasts," Biomed. Mater. Res., vol.34, pp.189-199, 1997. (Pubitemid 27073810)
12. H. Otsuka, A. Hirano, Y. Nagasaki, T. Okano, Y. Horiike, and K. Kataoka, "Two-dimensional multiarray formation of hepatoytes sphroids on a microfabricated PEG-brush surface," Chem- BioChem.,vol.5, pp.850-855, 2004. (Pubitemid 39257072)
13. S. Britland, P. Clark, P. Connolly, and G. Moores, "Micropatterned substrateum adhesiveness: a model for morphogenetic cues controlling cell behavior," Ex Cell Res., vol.198, pp.124-129, 1992.
14. J.J. Hickman, S.K. Bhatia, J.N. Quong, P. Shoen, and D.A. Stenger, "Rational pattern design for in vitro cellular networks using surface photochemistry," J. Vac. Sci. Technol., vol.12, pp.607-616, 1994.
15. A. Revzin, R.G. Tompkins, and M. Toner, "Surface engineering with poly(ethylene glycol) photolithography to create high-density cell arrays on glass," Langmuir., vol.19, pp.9855-9862, 2003.
16. A. Revzin, R.G. Tompkins, and M. Toner, "Surface engineering with poly (ethylene glycol) photolithography to create high-density cell arrays on glass," Langmuir, vol.19, pp.9855-9862, 2003.
17. J.M. Harris, eds., Poly(ethylene glycol) Chemistry. Biotechnical and Biomedical Applications, Plenum Press, New York, 1992.
18. W. Gombotz, W. Guanghui, T. Horbett, and A. Hoffman, "Protein adsorption to poly (ethylene oxide) surfaces," J. Biomed. Mater. Res., vol.25, pp.1547-1562, 1991.
19. H. Otsuka, Y. Akiyama, Y. Nagasaki, and K. Kataoka, "Quantitative and reversible lectin-induced association of gold nanoparticles modified with α-Lactosyl-ω-mercapto-(ethylene glycol)," J. Am. Chem. Soc., vol.123, pp.8226-8230, 2001. (Pubitemid 32916399)
20. V.A. Liu, W.E. Jastromb, and S.N. Bhatia, "Engineering protein and cell adhesivity using PEO-terminated triblock polymers," J. Biomed. Mater. Res., vol.60, pp.126-134, 2002. (Pubitemid 34126994)
21. E. Ostuni, R.G. Chapman, M.N. Liang, G. Meluleni, G. Pier, and D.E. Ingber, "Self-assembled monolayers that resist the adsorption of proteins and the adhesion of bacterial and mammalian cells," Langmuir, vol.17, pp.6336-6343, 2001. (Pubitemid 35330713)
22. K. Matsumoto, H. Yoshitomi, J. Rossant, and K.S. Zaret, "Liver organogenesis promoted by endothelial cells prior to vascular function," Science, vol.294, pp.559-563, 2001. (Pubitemid 32999546)