Autism associated with low 5-hydroxyindolacetic acid in CSF and the heterozygous SLC6A4 gene Gly56Ala plus 5-HTTLPR L/L promoter variants

Molecular Genetics and Metabolism

Volumn 102, Issue 3, 2011, Pages 368-373

  Adamsen, Dea ^a,c,d   Meili, David ^a,c   Blau, Nenad ^a,c,d   Thöny, Beat ^a,c,d   Ramaekers, Vincent ^b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c Centre for Neuroscience (ZNZ)   (Switzerland)

^d Pediatric Research Center (PRC)   (Switzerland)

Author keywords

Atypical autism; CNS; Serotonin; SLC6A4

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; 5 HYDROXYTRYPTOPHAN; ALANINE; AMINE OXIDASE (FLAVIN CONTAINING); CARBIDOPA; GLYCINE; SEROTONIN; SEROTONIN TRANSPORTER;

ARTICLE; ATAXIA; AUTISM; CASE REPORT; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CHILD; COMPULSION; DEVELOPMENTAL DISORDER; GENE; GENE MUTATION; HETEROZYGOSITY; HUMAN; MACROCEPHALY; MALE; MUSCLE HYPOTONIA; NERVE FIBER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; SEROTONIN BRAIN LEVEL; SEROTONIN UPTAKE; SLC6A4 GENE; STEADY STATE; SYNAPSE VESICLE;

5-HYDROXYTRYPTOPHAN; AMINO ACID SUBSTITUTION; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; AUTISTIC DISORDER; CHILD, PRESCHOOL; GENOTYPE; HUMANS; HYDROXYINDOLEACETIC ACID; MALE; MUTATION; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TREATMENT OUTCOME;

EID: 79851515407     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2010.11.162     Document Type: Article

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