Synthesis and pharmacological evaluation of the individual stereoisomers of 3-[methyl(1,2,3,4-tetrahydro-2-naphthalenyl)amino]-1-indanone, a potent mast cell stabilising agent

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 4, 2011, Pages 1191-1194

  Byrne, Adam J ^a   Barlow, James W ^a   Walsh, John J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Allergy; Histamine; Mast cells

Indexed keywords

3 [METHYL(1,2,3,4 TETRAHYDRO 2 NAPHTHALENYL)AMINO] 1 INDANONE; ANTIALLERGIC AGENT; CROMOGLYCATE DISODIUM; INDANONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; MAST CELL; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; RAT; STEREOCHEMISTRY; STEREOISOMERISM;

2-NAPHTHYLAMINE; ANIMALS; CRYSTALLOGRAPHY, X-RAY; HISTAMINE; INDANS; MAST CELLS; MICE; MOLECULAR CONFORMATION; PASSIVE CUTANEOUS ANAPHYLAXIS; STEREOISOMERISM; SWINE;

RODENTIA;

EID: 79851510230     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.12.095     Document Type: Article

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