Synthesis and evaluation of dimeric 1,2,3,4-Tetrahydro-naphthalenylamine and Indan-1-ylamine derivatives with mast cell-stabilising and anti-allergic activity

European Journal of Medicinal Chemistry

Volumn 45, Issue 1, 2010, Pages 25-37

  Barlow, James W ^a   Walsh, John J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Anti allergic; Indanylamine; Mast cell stabilising; Tetrahydronaphthalenylamine

Indexed keywords

3 [(4 METHYLBENZYL)(1,2,3,4 TETRAHYDRO 2 NAPHTHALENYL)AMINO] 1 INDANONE; 3 [(7 METHOXY 1,2,3,4 TETRAHYDRO 1 NAPHTHALENYL)(METHYL)AMINO] 1 INDANONE; 3 [1,2,3,4 TETRAHYDRO 2 NAPHTHALENYL(3,4,5 TRIMEHOXYBENZYL)AMINO] 1 INDANONE; 3 [3,4 DIHYDRO 2H 4 CHROMENYL(METHYL)AMINO] 1 INDANONE; 3 [ALLYL(1,2,3,4 TETRAHYDRO 1 NAPHTHALENYL)AMINO] 1 INDANONE; 3 [ALLYL(1,2,3,4 TETRAHYDRO 2 NAPHTHALENYL)AMINO] 1 INDANONE; 3 [BENZYL(1,2,3,4 TETRAHYDRO 2 NAPHTHALENYL)AMINO] 1 INDANONE; 3 [METHYL(1,2,3,4 TETRAHYDRO 1 NAPHTHALENYL)AMINO] 1 INDANONE; 3 [METHYL(1,2,3,4 TETRAHYDRO 2 NAPHTHALENYL)AMINO] 1 INDANONE; 4 [2,3 DIHYDRO 1H 1 INDENYL(METHYL)AMINO] 1,2,3,4 TETRAHYDRO 1 NAPHTHALENONE; 4 [METHYL(1,2,3,4 TETRAHYDRO 1 NAPHTHALENYL)AMINO] 1,2,3,4 TETRAHYDRO 1 NAPHTHALENONE; 4 [METHYL(3 OXO 2,3 DIHYDRO 1H 1 INDENYL)AMINO] 1,2,3,4 TETRAHYDRO 1 NAPHTHALENONE; 5 METHOXY 3 [METHYL(1,2,3,4 TETRAHYDRONAPHTHALEN 1 YL)AMINO]INDAN 1 ONE; 7 METHOXY 3 [METHYL (1,2,3,4 TETRAHYDRONAPHTHALEN 1 YL)AMINO]INDAN 1 ONE; ANTIALLERGIC AGENT; CROMOGLYCATE DISODIUM; INDAN DERIVATIVE; METHYL N,N BIS(1,2,3,4 TETRAHYDRO 1 NAPHTHALENYL)AMINE; N1 (3 OXO 2,3 DIHYDRO 1H 1 INDENYL) N1 (1,2,3,4 TETRAHYDRO 1 NAPHTHALENYL)ACETAMIDE; NAPHTHALENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BROMINATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; MAST CELL DEGRANULATION; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; RAT; SUBSTITUTION REACTION;

1-NAPHTHYLAMINE; 2-NAPHTHYLAMINE; AMINES; ANIMALS; ANTI-ALLERGIC AGENTS; CELL DEGRANULATION; DIMERIZATION; FEMALE; INDANS; MAST CELLS; OXYGEN; PASSIVE CUTANEOUS ANAPHYLAXIS; RATS; RATS, WISTAR;

EID: 72049112829     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.09.020     Document Type: Article

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