-
1
-
-
34547110147
-
Tumor paint: A chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci
-
DOI 10.1158/0008-5472.CAN-06-3948
-
Veiseh, M.; Gabikian, P.; Bahrami, S. B.; Veiseh, O.; Zhang, M.; Hackman, R. C.; Ravanpay, A. C.; Stroud, M. R.; Kusuma, Y.; Hansen, S. J.; Kwok, D.; Munoz, N. M.; Sze, R. W.; Grady, W. M.; Greenberg,N. M.; Ellenbogen, R. G.; Olson, J. M. Tumor paint:A chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci. Cancer Res. 2007, 67, 6882-6888. (Pubitemid 47105535)
-
(2007)
Cancer Research
, vol.67
, Issue.14
, pp. 6882-6888
-
-
Veiseh, M.1
Gabikian, P.2
Bahrami, S.-B.3
Veiseh, O.4
Zhang, M.5
Hackman, R.C.6
Ravanpay, A.C.7
Stroud, M.R.8
Kusuma, Y.9
Hansen, S.J.10
Kwok, D.11
Munoz, N.M.12
Sze, R.W.13
Grady, W.M.14
Greenberg, N.M.15
Ellenbogen, R.G.16
Olson, J.M.17
-
2
-
-
21644450671
-
Optical and MRI multifunctional nanoprobe for targeting gliomas
-
DOI 10.1021/nl0502569
-
Veiseh, O.; Sun, C.; Gunn, J.; Kohler, N.; Gabikian, P.; Lee, D.; Bhattarai, N.; Ellenbogen, R.; Sze, R.; Hallahan, A.; Olson, J.; Zhang, M. Q. Optical and MRI multifunctional nanoprobe for targeting gliomas. Nano Lett. 2005, 5, 1003-1008. (Pubitemid 40925409)
-
(2005)
Nano Letters
, vol.5
, Issue.6
, pp. 1003-1008
-
-
Veiseh, O.1
Sun, C.2
Gunn, J.3
Kohler, N.4
Gabikian, P.5
Lee, D.6
Bhattarai, N.7
Ellenbogen, R.8
Sze, R.9
Hallahan, A.10
Olson, J.11
Zhang, M.12
-
3
-
-
0032211350
-
Use of chlorotoxin for targeting of primary brain tumors
-
Soroceanu, L.; Gillespie, Y.; Khazaeli, M. B.; Sontheimer, H. Use of chlorotoxin for targeting of primary brain tumors. Cancer Res. 1998, 58, 4871-4879. (Pubitemid 28503684)
-
(1998)
Cancer Research
, vol.58
, Issue.21
, pp. 4871-4879
-
-
Soroceanu, L.1
Gillespie, Y.2
Khazaeli, M.B.3
Sontheimer, H.4
-
4
-
-
0035983279
-
Chlorotoxin, a scorpion-derived peptide, specifically binds to gliomas and tumors of neuroectodermal origin
-
DOI 10.1002/glia.10083
-
Lyons, S. A.; O'Neal, J.; Sontheimer, H. Chlorotoxin, a scorpionderived peptide, specifically binds to gliomas and tumors of neuroectodermal origin. Glia 2002, 39, 162-173. (Pubitemid 34817056)
-
(2002)
GLIA
, vol.39
, Issue.2
, pp. 162-173
-
-
Lyons, S.A.1
O'Neal, J.2
Sontheimer, H.3
-
5
-
-
0026045413
-
Chloride channel inhibition by the venom of the scorpion Leiurus quinquestriatus
-
DeBin, J. A.; Strichartz, G. R. Chloride channel inhibition by the venom of the scorpion Leiurus quinquestriatus. Toxicon 1991, 29, 1403-1408.
-
(1991)
Toxicon
, vol.29
, pp. 1403-1408
-
-
Debin, J.A.1
Strichartz, G.R.2
-
6
-
-
0027466723
-
Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion
-
DeBin, J. A.; Maggio, J. E.; Strichartz, G. R. Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion. Am. J. Physiol. Cell Physiol. 1993, 264, C361-369. (Pubitemid 23072445)
-
(1993)
American Journal of Physiology - Cell Physiology
, vol.264
-
-
DeBin, J.A.1
Maggio, J.E.2
Strichartz, G.R.3
-
7
-
-
0028927315
-
NMR sequential assignments and solution structure of chlorotoxin, a small scorpion toxin that blocks chloride channels
-
Lippens, G.; Najib, J.; Wodak, S. J.; Tartar, A. NMR sequential assignments and solution structure of chlorotoxin, a small scorpion toxin that blocks chloride channels. Biochemistry 1995, 34, 13-21.
-
(1995)
Biochemistry
, vol.34
, pp. 13-21
-
-
Lippens, G.1
Najib, J.2
Wodak, S.J.3
Tartar, A.4
-
8
-
-
25444448796
-
Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the α-conotoxin MII
-
DOI 10.1073/pnas.0504613102
-
Clark, R. J.; Fischer, H.; Dempster, L.; Daly, N. L.; Rosengren, K. J.; Nevin, S. T.; Meunier, F. A.; Adams, D. J.; Craik, D. J. Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MII. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 13767-13772. (Pubitemid 41377653)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.39
, pp. 13767-13772
-
-
Clark, R.J.1
Fischer, H.2
Dempster, L.3
Daly, N.L.4
Rosengren, K.J.5
Nevin, S.T.6
Meunier, F.A.7
Adams, D.J.8
Craik, D.J.9
-
9
-
-
33750460621
-
Cyclic MrIA: A stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter
-
DOI 10.1021/jm060299h
-
Lovelace, E. S.; Armishaw, C. J.; Colgrave, M. L.; Wahlstrom, M. E.; Alewood, P. F.; Daly, N. L.; Craik, D. J. Cyclic MrIA: A stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter. J. Med. Chem. 2006, 49, 6561-6568. (Pubitemid 44657450)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.22
, pp. 6561-6568
-
-
Lovelace, E.S.1
Armishaw, C.J.2
Colgrave, M.L.3
Wahlstrom, M.E.4
Alewood, P.F.5
Daly, N.E.6
Craik, D.J.7
-
10
-
-
77953010796
-
Establishing regiocontrol of disulfide bond isomers of alphaconotoxin ImI via the synthesis of N-to-Ccyclic analogs
-
Armishaw, C. J.; Dutton, J. L.; Craik, D. J.; Alewood, P. F. Establishing regiocontrol of disulfide bond isomers of alphaconotoxin ImI via the synthesis ofN-to-Ccyclic analogs. Biopolymers 2010, 94, 307-313.
-
(2010)
Biopolymers
, vol.94
, pp. 307-313
-
-
Armishaw, C.J.1
Dutton, J.L.2
Craik, D.J.3
Alewood, P.F.4
-
11
-
-
77956502216
-
The engineering of an orally active conotoxin for the treatment of neuropathic pain
-
Clark, R. J.; Jensen, J.; Nevin, S. T.; Callaghan, B. P.; Adams, D. J.; Craik, D. J. The engineering of an orally active conotoxin for the treatment of neuropathic pain. Angew. Chem., Int. Ed. 2010, 49, 6545-6548.
-
(2010)
Angew. Chem. Int. Ed.
, vol.49
, pp. 6545-6548
-
-
Clark, R.J.1
Jensen, J.2
Nevin, S.T.3
Callaghan, B.P.4
Adams, D.J.5
Craik, D.J.6
-
12
-
-
67649547851
-
Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4
-
Swedberg, J. E.; Nigon, L. V.; Reid, J. C.; de Veer, S. J.; Walpole, C. M.; Stephens,C.R.; Walsh,T. P.;Takayama, T.K.;Hooper, J. D.; Clements, J. A.;Buckle, A.M.;Harris, J. M. Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4. Chem. Biol. 2009, 16, 633-643.
-
(2009)
Chem. Biol.
, vol.16
, pp. 633-643
-
-
Swedberg, J.E.1
Nigon, L.V.2
Reid, J.C.3
De Veer, S.J.4
Walpole, C.M.5
Stephens, C.R.6
Walsh, T.P.7
Takayama, T.K.8
Hooper, J.D.9
Clements, J.A.10
Buckle, A.M.11
Harris, J.M.12
-
13
-
-
34250008546
-
In situ neutralization in boc-chemistry solid phase peptide synthesis: Rapid, high yield assembly of difficult sequences
-
DOI 10.1007/s10989-006-9059-7, Bruce Merrifield Commemorative Issue
-
Schnolzer, M.; Alewood, P.; Jones, A.; Alewood, D.; Kent, S. B. H. In situ neutralization in boc-chemistry solid phase peptide synthesis - Rapid, high yield assembly of difficult sequences. Int. J. Pept. Res. Ther. 2007, 13, 31-44. (Pubitemid 46888447)
-
(2007)
International Journal of Peptide Research and Therapeutics
, vol.13
, Issue.1-2
, pp. 31-44
-
-
Schnolzer, M.1
Alewood, P.2
Jones, A.3
Alewood, D.4
Kent, S.B.H.5
-
14
-
-
77956502216
-
The engineering of an orally active conotoxin for the treatment of neuropathic pain
-
Clark, R. J.; Jensen, J.; Nevin, S. T.; Callaghan, B. P.; Adams, D. J.; Craik, D. J. The engineering of an orally active conotoxin for the treatment of neuropathic pain. Angew. Chem., Int. Ed. 2010, 49, 6545-6548.
-
(2010)
Angew. Chem. Int. Ed.
, vol.49
, pp. 6545-6548
-
-
Clark, R.J.1
Jensen, J.2
Nevin, S.T.3
Callaghan, B.P.4
Adams, D.J.5
Craik, D.J.6
-
15
-
-
0027944205
-
Synthesis of proteins by native chemical ligation
-
Dawson, P. E.; Muir, T. W.; Clarklewis, I.; Kent, S. B. H. Synthesis of proteins by native chemical ligation. Science 1994, 266, 776-779. (Pubitemid 24359280)
-
(1994)
Science
, vol.266
, Issue.5186
, pp. 776-779
-
-
Dawson, P.E.1
Muir, T.W.2
Clark-Lewis, I.3
Kent, S.B.H.4
-
16
-
-
0033549108
-
Thia Zip reaction for synthesis of large cyclic peptides: Mechanisms and applications
-
Tam, J. P.; Lu, Y.-A.; Yu, Q. Thia Zip reaction for synthesis of large cyclic peptides: mechanisms and applications. J. Am. Chem. Soc. 1999, 121, 4316-4324.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 4316-4324
-
-
Tam, J.P.1
Lu, Y.-A.2
Yu, Q.3
-
17
-
-
1542468131
-
Chemoselective backbone cyclization of unprotected peptides
-
Camarero, J. A.; Muir, T. W. Chemoselective backbone cyclization of unprotected peptides. Chem. Commun. 1997, 1369-1370. (Pubitemid 127496034)
-
(1997)
Chemical Communications
, Issue.15
, pp. 1369-1370
-
-
Camarero, J.A.1
Muir, T.W.2
-
18
-
-
0032536553
-
Chemical synthesis of a circular protein domain: Evidence for folding-assisted cyclization
-
Camarero, J. A.; Pavel, J.; Muir, T. W. Chemical synthesis of a circular protein domain: Evidence for folding-assisted cyclization. Angew. Chem., Int. Ed. 1998, 37, 347-349.
-
(1998)
Angew. Chem. Int. Ed.
, vol.37
, pp. 347-349
-
-
Camarero, J.A.1
Pavel, J.2
Muir, T.W.3
-
20
-
-
77749251974
-
Improving the power of diagnostics in the era of targeted therapy and personalized healthcare
-
Walk, E. E. Improving the power of diagnostics in the era of targeted therapy and personalized healthcare. Curr. Opin. Drug Discovery Dev. 2010, 13, 226-234.
-
(2010)
Curr. Opin. Drug Discovery Dev.
, vol.13
, pp. 226-234
-
-
Walk, E.E.1
-
21
-
-
77950505810
-
Anticancer drug development: The grand challenges
-
Hait, W. N. - Anticancer drug development: The grand challenges. Nat. Rev. Drug Discovery 2010, 9, 253-254.
-
(2010)
Nat. Rev. Drug Discovery
, vol.9
, pp. 253-254
-
-
Hait, W.N.1
-
22
-
-
34748922922
-
The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis
-
DOI 10.1016/j.biocel.2007.06.016, PII S1357272507002087
-
Greenwood, K. P.; Daly, N. L.; Brown, D. L.; Stow, J. L.; Craik, D. J. The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis. Int. J. Biochem. Cell Biol. 2007, 39, 2252-2264. (Pubitemid 47484280)
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, Issue.12
, pp. 2252-2264
-
-
Greenwood, K.P.1
Daly, N.L.2
Brown, D.L.3
Stow, J.L.4
Craik, D.J.5
-
23
-
-
30744437130
-
Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2
-
DOI 10.1007/s00018-005-5486-4
-
Herrmann, A.; Svangard, E.; Claeson, P.; Gullbo, J.; Bohlin, L.; Goransson, U. Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2. Cell. Mol. Life Sci. 2006, 63, 235-245. (Pubitemid 43100292)
-
(2006)
Cellular and Molecular Life Sciences
, vol.63
, Issue.2
, pp. 235-245
-
-
Herrmann, A.1
Svangard, E.2
Claeson, P.3
Gullbo, J.4
Bohlin, L.5
Goransson, U.6
-
24
-
-
0037423212
-
Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2
-
DOI 10.1074/jbc.M205662200
-
Deshane, J.; Garner, C. C.; Sontheimer, H. Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2. J. Biol. Chem. 2003, 278, 4135-4144. (Pubitemid 36801150)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.6
, pp. 4135-4144
-
-
Deshane, J.1
Garner, C.C.2
Sontheimer, H.3
-
25
-
-
0027462446
-
Expression of annexins on the surfaces of non-metastatic and metastatic human and rodent tumor cells
-
DOI 10.1007/BF00880064
-
Yeatman, T. J.; Updyke, T. V.; Kaetzel, M. A.; Dedman, J. R.; Nicolson, G. L. Expression of annexins on the surfaces of nonmetastatic and metastatic human and rodent tumor cells. Clin. Exp. Metastasis 1993, 11, 37-44. (Pubitemid 23045688)
-
(1993)
Clinical and Experimental Metastasis
, vol.11
, Issue.1
, pp. 37-44
-
-
Yeatman, T.J.1
Updyke, T.V.2
Kaetzel, M.A.3
Dedman, J.R.4
Nicolson, G.L.5
-
26
-
-
77951151896
-
Annexin A2 is a molecular target for TM601, a peptide with tumor-targeting and anti-angiogenic effects
-
Kesavan, K.; Ratliff, J.; Johnson, E. W.; Dahlberg, W.; Asara, J. M.; Misra, P.; Frangioni, J. V.; Jacoby, D. B. Annexin A2 is a molecular target for TM601, a peptide with tumor-targeting and anti-angiogenic effects. J. Biol. Chem. 2010, 285, 4366-4374.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 4366-4374
-
-
Kesavan, K.1
Ratliff, J.2
Johnson, E.W.3
Dahlberg, W.4
Asara, J.M.5
Misra, P.6
Frangioni, J.V.7
Jacoby, D.B.8
-
27
-
-
70349583511
-
Structure and biological activities of cyclotides
-
Daly, N. L.; Rosengren, K. J.; Craik, D. J. Discovery, structure and biological activities of cyclotides. Adv. Drug Delivery Rev. 2009, 61, 918-930.
-
(2009)
Adv. Drug Delivery Rev.
, vol.61
, pp. 918-930
-
-
Daly, N.L.1
Rosengren, K.J.2
Discovery, J.C.D.3
-
28
-
-
70349439112
-
"Splicing up" drug discovery. Cellbased expression and screening of genetically-encoded libraries of backbone-cyclized polypeptides
-
Sancheti, H.; Camarero, J. A. "Splicing up" drug discovery. Cellbased expression and screening of genetically-encoded libraries of backbone-cyclized polypeptides. Adv. Drug Delivery Rev. 2009, 61, 908-917.
-
(2009)
Adv. Drug Delivery Rev.
, vol.61
, pp. 908-917
-
-
Sancheti, H.1
Camarero, J.A.2
-
29
-
-
7444228699
-
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of Sonic Hedgehog-induced medulloblastomas
-
DOI 10.1158/0008-5472.CAN-04-1813
-
Hallahan, A. R.; Pritchard, J. I.; Hansen, S.; Benson,M.; Stoeck, J.; Hatton, B. A.; Russell, T. L.; Ellenbogen, R. G.; Bernstein, I. D.; Beachy, P. A.; Olson, J. M. The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehoginduced medulloblastomas. Cancer Res. 2004, 64, 7794-7800. (Pubitemid 39446912)
-
(2004)
Cancer Research
, vol.64
, Issue.21
, pp. 7794-7800
-
-
Hallahan, A.R.1
Pritchard, J.I.2
Hansen, S.3
Benson, M.4
Stoeck, J.5
Hatton, B.A.6
Russell, T.L.7
Ellenbogen, R.G.8
Bernstein, I.D.9
Beachy, P.A.10
Olson, J.M.11
-
30
-
-
40949158954
-
The Smo/Smo model: Hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread
-
DOI 10.1158/0008-5472.CAN-07-5092
-
Hatton, B. A.; Villavicencio, E. H.; Tsuchiya, K. D.; Pritchard, J. I.; Ditzler, S.; Pullar, B.; Hansen, S.; Knoblaugh, S. E.; Lee, D.; Eberhart, C. G.; Hallahan, A. R.; Olson, J. M. The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread. Cancer Res. 2008, 68, 1768-1776. (Pubitemid 351416562)
-
(2008)
Cancer Research
, vol.68
, Issue.6
, pp. 1768-1776
-
-
Hatton, B.A.1
Villavicencio, E.H.2
Tsuchiya, K.D.3
Pritchard, J.I.4
Ditzler, S.5
Pullar, B.6
Hansen, S.7
Knoblaugh, S.E.8
Lee, D.9
Eberhart, C.G.10
Hallahan, A.R.11
Olson, J.M.12
-
31
-
-
0029364052
-
1H, 13C and 15N chemical shift referencing in biomolecular NMR
-
Wishart, D. S.; Bigam, C. G.; Yao, J.; Abildgaard, F.; Dyson, H. J.; Oldfield, E.; Markley, J. L.; Sykes, B. D. 1H, 13C and 15N chemical shift referencing in biomolecular NMR. J. Biomol. NMR 1995, 6, 135-140.
-
(1995)
J. Biomol. NMR
, vol.6
, pp. 135-140
-
-
Wishart, D.S.1
Bigam, C.G.2
Yao, J.3
Abildgaard, F.4
Dyson, H.J.5
Oldfield, E.6
Markley, J.L.7
Sykes, B.D.8
|