Extracellular loops of the Eschericia coli outer membrane protein A contribute to the pathogenesis of meningitis

Journal of Infectious Diseases

Volumn 203, Issue 1, 2011, Pages 131-140

  Maruvada, Ravi ^a   Kim, Kwang Sik ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CYTOSOLIC PHOSPHOLIPASE A2; KANAMYCIN; OUTER MEMBRANE PROTEIN A; STREPTOMYCIN;

ARTICLE; BACTERIAL MENINGITIS; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BRAIN BLOOD VESSEL; CELL INVASION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

BACTERIAL OUTER MEMBRANE PROTEINS; BLOOD BACTERICIDAL ACTIVITY; CELLS, CULTURED; ENDOTHELIAL CELLS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; GROUP IV PHOSPHOLIPASES A2; HOST-PATHOGEN INTERACTIONS; HUMANS; INFANT, NEWBORN; MENINGITIS, BACTERIAL; MICROBIAL VIABILITY; SEQUENCE DELETION; SERUM; VIRULENCE FACTORS;

EID: 79851491312     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jiq009     Document Type: Article

References (33)

1. Klinger G, Chin CN, Beyene J, Perlman M. Predicting the outcome of neonatal bacterial meningitis. Pediatrics 2000; 106:477-82. (Pubitemid 30664131)
2. Holt DE, Halket S, de Louvois J, Harvey D. Neonatal meningitis in England and Wales: 10 years on. Arch Dis Child Fetal Neonatal Ed 2001; 84:F85-9.
3. Stevens JP, Eames M, Kent A, Halket S, Holt D, Harvey D. Long-term outcome of neonatal meningitis. Arch Dis Child Fetal Neonatal Ed 2003; 88:F179-84.
4. Chang CJ, Chang WN, Huang LT, et al. Bacterial meningitis in infants: the epidemiology, clinical features, and prognostic factors. Brain Dev 2004; 26:168-75.
5. Smith PB, Cotton CM, Garges HP, et al. A comparison of neonatal Gram-negative rod and Gram-positive cocci meningitis. J Perinatol 2006; 26:111-4.
6. Kim KS. Neurological diseases: Pathogenesis of bacterial meningitis: from bacteraemia to neuronal injury. Nat Rev Neurosci 2003; 4:376-85. (Pubitemid 37280176)
7. Kim KS. Mechanisms of microbial traversal of the blood-brain barrier. Rev Nat Rev Microbiol 2008; 6:625-34.
8. Huang SH, Wass CA, Fu Q, Prasadarao NV, Stins MF, et al. E. coli invasion of brain microvascular endothelial cells in vitro and in vivo: molecular cloning and characterization of invasion gene ibe10. Infect Immun 1995; 63:4470-5.
9. Huang SH, Chen YH, Fu Q, et al. Identification and characterization of an E. coli invasion gene locus, ibeB, required for penetration of brain microvascular endothelial cells. Infect Immun 1999; 67:2103-9. (Pubitemid 29200459)
10. Wang Y, Huang SH, Wass CA, Stins MF, Kim KS. The gene locus yijP contributes to E. coli K1 invasion of brain microvascular endothelial cells. Infect Immun 1999; 67:4751-6. (Pubitemid 29400460)
11. Teng CH, Cai M, Shin S, et al. Escherichia coli K1 RS218 interacts with human brain microvascular endothelial cells via Type 1 fimbriae. Infect Immun 2005; 73:2923-31. (Pubitemid 40570361)
12. Khan NA, Wang Y, Kim KJ, et al. Cytotoxic necrotizing factor-1 contributes to E. coli K1 invasion of the central nervous system. J Biol Chem 2002; 277:15607-12. (Pubitemid 34967831)
13. Prasadarao NV, Wass CA, Weiser JN, et al. Outer membrane protein A of E. coli contributes to invasion of brain microvascular endothelial cells. Infect Immun 1996; 64:146-53. (Pubitemid 26009353)
14. Parthasarathy G, Yao Kim. KS Flagella promote E. coli K1 association with and invasion of human brain microvascular endothelial cells. Infect Immun 2007; 75:2937-45. (Pubitemid 46870175)
15. Nègre VL, Bonacorsi S, Schubert S, et al. The siderophore receptor IroN, but not the high-pathogenicity Island or the hemin receptor ChuA, contributes to the bacteremic step of Escherichia coli neonatal meningitis. Infect Immun 2004; 72:1216-20. (Pubitemid 38166714)
16. Hoffman JA, Wass C, Stins MF, Kim KS. The capsule supports survival but not traversal of E. coli K1 across the blood-brain barrier. Infect Immun 1999; 67:3566-70. (Pubitemid 29291530)
17. Maruvada R, Blom AM, Prasadarao NV. Effects of complement regulators bound to E. coli K1 and Group B Streptococcus on the interaction with host cells. Immunology 2008; 124:265-276. (Pubitemid 351692907)
18. Shin S, Lu G, Cai M, Kim KS. E. coli outer membrane protein A adheres to human brain microvascular endothelial cells. Biochem Biophys Res Commun 2005; 330:1199-204.
19. Teng CH, Xie Y, Shin S, et al. Effects of ompA deletion on Escherichia coli K1 strain RS218's type 1 fimbria expression and association with human brain microvascular endothelial cells. Infect Immun 2006; 74:5609-16. (Pubitemid 44484544)
20. Weiser JN, Gotschlich EC. Outer membrane protein A (OmpA) contributes to serum resistance and pathogenicity of E. coli K-1. Infect Immun 1991; 59:2252-8.
21. Koebnik R. Structural and Functional Roles of the Surface-Exposed Loops of the b2Barrel Membrane Protein OmpA from E. coli. J Bacteriol 1999; 181:3688-94. (Pubitemid 29283795)
22. Ried G, Koebnik R, Hindennach I, Mutschler B, Henning U. Membrane topology and assembly of the outer membrane protein OmpA of E. coli K-12. Mol Gen Genet 1994; 243:127-35. (Pubitemid 24146409)
23. Datta D, Vaidehi N, Floriano WB, et al. Interaction of E. coli outermembrane protein A with sugars on the receptors of the brain microvascular endothelial cells. Proteins 2003; 50:213-21. (Pubitemid 36055600)
24. Prasadarao NV, Wass CA, Kim KS. Endothelial cell GlcNAc beta 1-4GlcNAc epitopes for outer membrane protein A enhance traversal of E. coli across the blood-brain barrier. Infect Immun 1996; 64:154-60.
25. Smith SGJ, Mahon V, Lambert MA, Fagan RP. A molecular Swiss army knife: OmpA structure, function and expression. FEMS Microbiol Lett 2007; 273:1-11. (Pubitemid 47024891)
26. Stins MF, Giles F, Kim KS. Selective expression of adhesion molecules on human brain microvascular endothelial cells. J Neuroimmunol 1997; 76:81-90. (Pubitemid 27272632)
27. Das A, Asatryan L, Reddy MA, et al. Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia cells and Listeria monocytogenes. J Infect Dis 2001; 184:732-37. (Pubitemid 32826424)
28. Cho SH, You HJ,Woo CH, Yoo YJ, Kim JH. Rac and protein kinase C-a regulate ERKs and cytosolic phospholipase A2 in FccRI signaling to cysteinyl leukotriene synthesis in mast cells. J Immunol 2004; 173:624-31.
29. Ghosh M, Tucker DE, Burchett SA, Leslie CC. Properties of the group IV phospholipase A2 family. Prog Lipid Res 2006; 45:487-510.
30. Prasadarao NV, Srivastava PK, Rudrabhatla SV, Kim KS, Huang SH, Sukumaran SK. Cloning and expression of the E. coli K1 outer membrane protein A receptor, a gp96 homologue. Infect Immun 2003; 71:1680-8. (Pubitemid 36368697)
31. Khan NA, Shin S, Chung JW, Kim KJ, et al. Outer membrane protein A and cytotoxic necrotizing factor-1 use diverse signaling mechanisms for E. coli K1 invasion of human brain microvascular endothelial cells. Micro Pathog 2003; 35:35-42. (Pubitemid 36809188)
32. Tucker DE, Gijón MA, Spencer DM, et al. Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages. J Leukoc Biol 2008; 84:798-806.
33. Pautsch A, Schulz GE. Structure of the outer membrane protein A transmembrane domain. Nat Struct Biol 1998; 5:1013-7. (Pubitemid 28506635)