Macrophage Migratory Inhibitory Factor (MIF) may be a key factor in inflammation in obstructive sleep apnea

Sleep

Volumn 34, Issue 2, 2011, Pages 161-163

  Edwards, Kate M ^a   Tomfohr, Lianne M ^a,b   Mills, Paul J ^a,b   Bosch, Jos A ^c,d   Ancoli Israel, Sonia ^a,b   Loredo, Jose S ^e   Dimsdale, Joel ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN DIEGO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Cortisol; Inflammation; MIF; Obstructive sleep apnea

Indexed keywords

GLUCOCORTICOID; HYDROCORTISONE; MACROPHAGE MIGRATION INHIBITION FACTOR;

ADULT; ANTIINFLAMMATORY ACTIVITY; AREA UNDER THE CURVE; AROUSAL; ARTICLE; BLOOD SAMPLING; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; FEMALE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; NIGHT SLEEP; POLYSOMNOGRAPHY; PRIORITY JOURNAL; SLEEP APNEA SYNDROME;

EID: 79851487058     PISSN: 01618105     EISSN: 15509109     Source Type: Journal    
DOI: 10.1093/sleep/34.2.161     Document Type: Article

References (10)

1. Ryan S, Taylor CT, McNicholas WT. Systemic inflammation: a key factor in the pathogenesis of cardiovascular complications in obstructive sleep apnoea syndrome? Thorax 2009;64:631-636.
2. Trayhurn P, Wang B, Wood IS. Hypoxia and the endocrine and signalling role of white adipose tissue. Arch Physiol Biochem 2008;114:267-276.
3. Calandra T, Bernhagen J, Metz CN, et al. MIF as a glucocorticoid-induced modulator of cytokine production. Nature 1995;377:68-71.
4. Bucala R. MIF re-discovered: pituitary hormone and glucocorticoid-induced regulator of cytokine production. Cytokine Growth Factor Rev 1996;7:19-24. (Pubitemid 27202662)
5. Schmoller A, Eberhardt F, Jauch-Chara K, et al. Continuous positive airway pressure therapy decreases evening cortisol concentrations in patients with severe obstructive sleep apnea. Metabolism 2009;58:848-853.
6. Vgontzas AN, Pejovic S, Zoumakis E, et al. Hypothalamic-pituitaryadrenal axis activity in obese men with and without sleep apnea: effects of continuous positive airway pressure therapy. J Clin Endocrinol Metab 2007;92:4199-207. (Pubitemid 350074732)
7. Petrovsky N, Socha L, Silva D, et al. Macrophage migration inhibitory factor exhibits a pronounced circadian rhythm relevant to its role as a glucocorticoid counter-regulator. Immunol Cell Biol 2003;81:137-43. (Pubitemid 36403424)
8. Mills PJ, Natarajan L, von Kanel R, Ancoli-Israel S, Dimsdale JE. Diurnal variability of C-reactive protein in obstructive sleep apnea. Sleep Breath 2009;13:415-20.
9. Rechtschaffen A, Kales A. A manual of standardized terminology, techniques and scoring system of sleep stages in human subjects. Los Angeles: Brain Information Service/Brain Research Institute, University of California Los Angeles; 1968.
10. Mizue Y, Nishihira J, Miyazaki T, et al. Quantitation of macrophage migration inhibitory factor (MIF) using the one-step sandwich enzyme immunosorbent assay: elevated serum MIF concentrations in patients with autoimmune diseases and identification of MIF in erythrocytes. Int J Mol Med 2000;5:397-403.