Suppressing the formation of osteoclasts using bioactive components of the edible mushroom Leccinum extremiorientale (L. Vass.) singer (Agaricomycetideae)

International Journal of Medicinal Mushrooms

Volumn 12, Issue 4, 2010, Pages 401-406

  Choi, Jae Hoon ^a   Ozawa, Nobuhiko ^a   Masuda, Kikuko ^b   Koyama, Tomoyuki ^b   Yazawa, Kazunaga ^b   Kawagishi, Hirokazu ^a  

^a SHIZUOKA UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Leccinum extremiorientale; Medicinal mushrooms; Osteoclast formation; Sterol; Suppressing substance

Indexed keywords

5ALPHA,6ALPHA EPOXY ERGOSTA 8(14),22 DIENE 3BETA,7ALPHA DIOL; 5ALPHA,6ALPHA EPOXY ERGOSTA 8,22 DIENE 3BETA,7ALPHA DIOL; LECCINUM EXTREMIORIENTALE EXTRACT; PLANT EXTRACT; STEROL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CELL ASSAY; CELL DIFFERENTIATION; COCULTURE; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; LECCINUM EXTREMIORIENTALE; MASS SPECTROMETRY; MUSHROOM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OSTEOCLAST; OSTEOPOROSIS; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

BASIDIOMYCOTA; LECCINUM; LECCINUM EXTREMIORIENTALE;

EID: 79851468787     PISSN: 15219437     EISSN: 19404344     Source Type: Journal    
DOI: 10.1615/IntJMedMushr.v12.i4.70     Document Type: Article

References (10)

1. Kawagishi H, Akachi T, Ogawa T, Masuda K, Yamaguchi K, Yazawa K, Takahashi M. Chaxine A, an osteoclastforming suppressing substance, from the mushroom Agrocybe chaxingu. Heterocycles. 2006;69:253-8.
2. Choi J-H, Abe N, Masuda K, Koyama T, Yazawa K, Kawagishi H. Osteoclast-forming suppressing compounds from the edible mushroom Agrocybe chaxingu Huang. Int J Med Mushr. 2010;12:151-5.
3. Choi J-H, Abe N, Masuda K, Koyama T, Yazawa K, Kawagishi H. Chaxines B, C, D and E from the edible mushroom Agrocybe chaxingu. Tetrahedron. 2009;65:9850-3.
4. Kawagishi H, Hota K, Masuda K, Yamaguchi K, Yazawa K, Shibata K, Uzuka N, Matahira Y. Osteoclast-forming suppressive compounds from Makomotake, Zizania latifolia infected with Ustilago esculenta. Biosci Biotechnol Biochem. 2006;70:2800-2.
5. Wani MR, Fuller K, Kim NS, Choi Y, Chambers T. Prostaglandin E2 cooperates with TRANCE in osteoclast induction from hemopoietic precursors: Synergistic activation of differentiation, cell spreading, and fusion. Endocrinology. 1999;140:1927-35. (Pubitemid 29149267)
6. Takami M, Woo JT, Nagai K. Osteoblastic cells induce fusion and activation of osteoclasts through a mechanism independent of macrophage-colony-stimulating factor production. Cell Tissue Res. 1999;298:327-34. (Pubitemid 29512084)
7. Greca MD, Fiorentino A, Molinaro A, Monaco P, Previtera L. Steroidal 5,6-epoxides from Arum italicum. Nat Prod Lett. 1993;2:27-32.
8. Ishizuka T, Yaoita Y, Kikuchi M. Sterol constituents from the fruit bodies of Grifola frondosa (Fr.). Chem Pharm Bull. 1997;45:1756-60. (Pubitemid 28550456)
9. Yaoita Y, Endo M, Tani Y, Machida K, Amemiya K. Sterol constituents from seven mushrooms. Chem Pharm Bull. 1999;47:847-51. (Pubitemid 29315375)
10. Luo X, Li F, Shinde PB, Hong J, Lee C-O, Im KS, Jung JH. 26,27-Cyclosterols and other polyoxygenated sterols from a marine sponge Topsentia sp. J Nat Prod. 2006;69:1760-8. (Pubitemid 46144972)