-
25
-
-
0034900174
-
-
P.F. Bross, J. Beitz, G. Chen, X.H. Chen, E. Duffy, L. Kieffer, S. Roy, R. Sridhara, A. Rahman, G. Williams, and R. Pazdur Clin. Cancer Res. 7 2001 1490
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1490
-
-
Bross, P.F.1
Beitz, J.2
Chen, G.3
Chen, X.H.4
Duffy, E.5
Kieffer, L.6
Roy, S.7
Sridhara, R.8
Rahman, A.9
Williams, G.10
Pazdur, R.11
-
26
-
-
0141495545
-
-
M.W. Perpall, K.P.U. Perera, J. DiMaio, J. Ballato, S.H. Foulger, and D.W. Smith Jr. Langmuir 19 2003 7153
-
(2003)
Langmuir
, vol.19
, pp. 7153
-
-
Perpall, M.W.1
Perera, K.P.U.2
Dimaio, J.3
Ballato, J.4
Foulger, S.H.5
Smith Jr., D.W.6
-
33
-
-
0030444099
-
-
C.C. Chen, W.C. Hsin, N.F. Ko, Y.L. Huang, C.J. Ou, and C.M. Teng J. Nat. Prod. 59 1996 1149
-
(1996)
J. Nat. Prod.
, vol.59
, pp. 1149
-
-
Chen, C.C.1
Hsin, W.C.2
Ko, N.F.3
Huang, Y.L.4
Ou, C.J.5
Teng, C.M.6
-
35
-
-
33747432610
-
-
N. Vasile, Elfahmi, R. Boss, O. Kayser, G. Momekov, S. Konstantinov, and I. Ionkova J. Nat. Prod. 69 2006 1014
-
(2006)
J. Nat. Prod.
, vol.69
, pp. 1014
-
-
Vasile, N.1
Elfahmi2
Boss, R.3
Kayser, O.4
Momekov, G.5
Konstantinov, S.6
Ionkova, I.7
-
36
-
-
37049083667
-
-
K. Kobayashi, Y. Kanno, S. Seko, and H. Suginomi J. Chem. Soc., Perkin Trans. 1 1992 3111
-
(1992)
J. Chem. Soc., Perkin Trans.
, vol.1
, pp. 3111
-
-
Kobayashi, K.1
Kanno, Y.2
Seko, S.3
Suginomi, H.4
-
40
-
-
79751529805
-
-
A.S. Capilla, I. Sanchez, D.H. Caignard, P. Renard, and M.D. Pujol Eur. J. Med. Chem. 42 2001 437
-
(2001)
Eur. J. Med. Chem.
, vol.42
, pp. 437
-
-
Capilla, A.S.1
Sanchez, I.2
Caignard, D.H.3
Renard, P.4
Pujol, M.D.5
-
41
-
-
3042706907
-
-
S.K. Sagar, C.C. Chang, W.K. Wang, J.Y. Lin, and S.S. Lee Bioorg. Med. Chem. 12 2004 4045
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 4045
-
-
Sagar, S.K.1
Chang, C.C.2
Wang, W.K.3
Lin, J.Y.4
Lee, S.S.5
-
43
-
-
79751537908
-
-
The correct IUPAC name of the isofuran derivative is 1,3-dihydro- naphtho[2,3-c]furan
-
The correct IUPAC name of the isofuran derivative is 1,3-dihydro- naphtho[2,3-c]furan.
-
-
-
-
44
-
-
79751524666
-
-
note
-
4. The ethyl acetate was then evaporated and product was isolated by column chromatography (Si-gel, petroleum ether-ethyl acetate mixture as eluent). For benzylic oxidation: Equal weights of potassium permanganate and copper sulfate pentahydrate were ground together in a mortar. The resulting fine, highly coloured product was used as a heterogeneous oxidant (3.2 g for 1.4 mmol) in a methylene chloride solution of dihydroisofuran derivative and stirred vigorously under gentle reflux for 72 h. The resulting mixture was then filtered through a Celite pad and concentrated. The products were isolated by column chromatography (Si-gel, petroleum ether-ethyl acetate mixture as eluent).
-
-
-
-
45
-
-
79751536717
-
-
A detailed study on the electronic effect on GB cyclization has been carried out using other electron withdrawing groups like nitro and cyano: Maji, M.; Mallick, D.; Mondal, S.; Anoop, A.; Bag, S. S.; Basak, A.; Jemmis, E. D. Org. Lett., accepted for publication. Manuscript under preparation. In the present work, benzoate was used as the electron withdrawing group as it could be readily hydrolysed to the phenol.
-
A detailed study on the electronic effect on GB cyclization has been carried out using other electron withdrawing groups like nitro and cyano: Maji, M.; Mallick, D.; Mondal, S.; Anoop, A.; Bag, S. S.; Basak, A.; Jemmis, E. D. Org. Lett., accepted for publication. Manuscript under preparation. In the present work, benzoate was used as the electron withdrawing group as it could be readily hydrolysed to the phenol.
-
-
-
-
46
-
-
79751538152
-
-
The selectivity showed by the reaction indicated that the benzoate was hydrolysed after the GB process.
-
The selectivity showed by the reaction indicated that the benzoate was hydrolysed after the GB process.
-
-
-
-
48
-
-
79751534302
-
-
note
-
+ 381.1338; found 381.1347.
-
-
-
|