Mechanisms involved in extraterritorial facial pain following cervical spinal nerve injury in rats

Molecular Pain

Volumn 7, Issue , 2011, Pages

  Kobayashi, Azusa ^a   Shinoda, Masamichi ^a   Sessle, Barry J ^b   Honda, Kuniya ^a   Imamura, Yoshiki ^a   Hitomi, Suzuro ^a   Tsuboi, Yoshiyuki ^a   Okada Ogawa, Akiko ^a   Iwata, Koichi ^a  

^a NIHON UNIVERSITY   (Japan)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MITOGEN ACTIVATED PROTEIN KINASE 1; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL COUNT; CERVICAL SPINAL NERVE INJURY; CONTROLLED STUDY; DEFENSIVE BEHAVIOR; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FACE PAIN; IMMUNOCOMPETENT CELL; MALE; MECHANICAL STIMULATION; NERVE INJURY; NERVE TRANSECTION; NEUROPATHOLOGY; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; THERMAL STIMULATION; TRIGEMINAL NUCLEUS; ANIMAL; CERVICAL SPINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; HEAT; IMMUNOHISTOCHEMISTRY; INJURY; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; POSTERIOR HORN CELL; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; BEHAVIOR, ANIMAL; CERVICAL VERTEBRAE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FACIAL PAIN; FLAVONOIDS; HOT TEMPERATURE; IMMUNOHISTOCHEMISTRY; MALE; PHOSPHORYLATION; POSTERIOR HORN CELLS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES; TRIGEMINAL CAUDAL NUCLEUS;

EID: 79751529383     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-7-12     Document Type: Article

References (41)

1. Sessle BJ. Neural mechanisms and pathways in craniofacial pain. Can J Neurol Sci 1999, 26(Suppl 3):S7-11.
2. Hsieh GC, Pai M, Chandran P, Hooker BA, Zhu CZ, Salyers AK, Wensink EJ, Zhan C, Carroll WA, Dart MJ, et al. Central and peripheral sites of action for CB(2) receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats. Br J Pharmacol 2011, 162(2):428-40. 10.1111/j.1476-5381.2010.01046.x, 20880025.
3. Wu G, Ringkamp M, Hartke TV, Murinson BB, Campbell JN, Griffin JW, Meyer RA. Early onset of spontaneous activity in uninjured C-fiber nociceptors after injury to neighboring nerve fibers. J Neurosci 2001, 21:RC140.
4. Ultenius C, Linderoth B, Meyerson BA, Wallin J. Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat. Neurosci Lett 2006, 399:85-90. 10.1016/j.neulet.2006.01.018, 16469445.
5. Aita M, Byers MR, Chavkin C, Xu M. Trigeminal injury causes kappa opioid-dependent allodynic, glial and immune cell responses in mice. Mol Pain 6:8. 10.1186/1744-8069-6-8, 2826348, 20109235.
6. Maihofner C, Nickel FT, Seifert F. [Neuropathic pain and neuroplasticity in functional imaging studies]. Schmerz 24:137-145. 10.1007/s00482-010-0902-6, 20376602.
7. Iwata K, Masuda Y, Ren K. Trigeminal neuronal recording in animal models of orofacial pain. Methods Mol Med 2004, 99:123-137.
8. Kitagawa J, Takeda M, Suzuki I, Kadoi J, Tsuboi Y, Honda K, Matsumoto S, Nakagawa H, Tanabe A, Iwata K. Mechanisms involved in modulation of trigeminal primary afferent activity in rats with peripheral mononeuropathy. Eur J Neurosci 2006, 24:1976-1986. 10.1111/j.1460-9568.2006.05065.x, 17040479.
9. Tsuboi Y, Takeda M, Tanimoto T, Ikeda M, Matsumoto S, Kitagawa J, Teramoto K, Simizu K, Yamazaki Y, Shima A, et al. Alteration of the second branch of the trigeminal nerve activity following inferior alveolar nerve transection in rats. Pain 2004, 111:323-334. 10.1016/j.pain.2004.07.014, 15363876.
10. Saito K, Hitomi S, Suzuki I, Masuda Y, Kitagawa J, Tsuboi Y, Kondo M, Sessle BJ, Iwata K. Modulation of trigeminal spinal subnucleus caudalis neuronal activity following regeneration of transected inferior alveolar nerve in rats. J Neurophysiol 2008, 99:2251-2263. 10.1152/jn.00794.2007, 18337368.
11. Okada-Ogawa A, Suzuki I, Sessle BJ, Chiang CY, Salter MW, Dostrovsky JO, Tsuboi Y, Kondo M, Kitagawa J, Kobayashi A, et al. Astroglia in medullary dorsal horn (trigeminal spinal subnucleus caudalis) are involved in trigeminal neuropathic pain mechanisms. J Neurosci 2009, 29:11161-11171. 10.1523/JNEUROSCI.3365-09.2009, 2804401, 19741123.
12. Piao ZG, Cho IH, Park CK, Hong JP, Choi SY, Lee SJ, Lee S, Park K, Kim JS, Oh SB. Activation of glia and microglial p38 MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury. Pain 2006, 121:219-231. 10.1016/j.pain.2005.12.023, 16495005.
13. Shinozaki T, Sakamoto E, Shiiba S, Ichikawa F, Arakawa Y, Makihara Y, Abe S, Ogawa A, Tsuboi E, Imamura Y. Cervical plexus block helps in diagnosis of orofacial pain originating from cervical structures. Tohoku J Exp Med 2006, 210:41-47. 10.1620/tjem.210.41, 16960344.
14. La Touche R, Paris-Alemany A, von Piekartz H, Mannheimer JS, Fernandez-Carnero J, Rocabado M. The Influence of Cranio-cervical Posture on Maximal Mouth Opening and Pressure Pain Threshold in Patients With Myofascial Temporomandibular Pain Disorders. Clin J Pain 2011, 27(1):48-55. 10.1097/AJP.0b013e3181edc157, 20733480.
15. Corbacelli A, Cutilli T, Marinangeli F, Ciccozzi A, Corbacelli C, Necozione S, Masedu F, Varrassi G. Cervical pain and headache in patients with facial asymmetries: the effect of orthognathic surgical correction. Minerva Anestesiol 2007, 73:281-289.
16. Sessle BJ, Hu JW, Amano N, Zhong G. Convergence of cutaneous, tooth pulp, visceral, neck and muscle afferents onto nociceptive and non-nociceptive neurones in trigeminal subnucleus caudalis (medullary dorsal horn) and its implications for referred pain. Pain 1986, 27:219-235. 10.1016/0304-3959(86)90213-7, 3797017.
17. Balasubramanyan S, Stemkowski PL, Stebbing MJ, Smith PA. Sciatic chronic constriction injury produces cell-type-specific changes in the electrophysiological properties of rat substantia gelatinosa neurons. J Neurophysiol 2006, 96:579-590. 10.1152/jn.00087.2006, 16611846.
18. Black JA, Cummins TR, Plumpton C, Chen YH, Hormuzdiar W, Clare JJ, Waxman SG. Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons. J Neurophysiol 1999, 82:2776-2785.
19. Gold MS, Weinreich D, Kim CS, Wang R, Treanor J, Porreca F, Lai J. Redistribution of Na(V)1.8 in uninjured axons enables neuropathic pain. J Neurosci 2003, 23:158-166.
20. Yamanaka H, Obata K, Fukuoka T, Dai Y, Kobayashi K, Tokunaga A, Noguchi K. Tissue plasminogen activator in primary afferents induces dorsal horn excitability and pain response after peripheral nerve injury. Eur J Neurosci 2004, 19:93-102. 10.1046/j.1460-9568.2003.03080.x, 14750967.
21. Zhang Z, Dellon AL. Facial pain and headache associated with brachial plexus compression in the thoracic inlet. Microsurgery 2008, 28:347-350. 10.1002/micr.20507, 18561268.
22. Mellick LB, Mellick GA. Treatment of acute orofacial pain with lower cervical intramuscular bupivacaine injections: a 1-year retrospective review of 114 patients. J Orofac Pain 2008, 22:57-64.
23. Vos BP, Strassman AM, Maciewicz RJ. Behavioral evidence of trigeminal neuropathic pain following chronic constriction injury to the rat's infraorbital nerve. J Neurosci 1994, 14:2708-2723.
24. Bennett GJ, Xie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 1988, 33:87-107. 10.1016/0304-3959(88)90209-6, 2837713.
25. Pezet S, Malcangio M, Lever IJ, Perkinton MS, Thompson SW, Williams RJ, McMahon SB. Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn. Mol Cell Neurosci 2002, 21:684-695. 10.1006/mcne.2002.1205, 12504600.
26. Xia Z, Dudek H, Miranti CK, Greenberg ME. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J Neurosci 1996, 16:5425-5436.
27. Noma N, Tsuboi Y, Kondo M, Matsumoto M, Sessle BJ, Kitagawa J, Saito K, Iwata K. Organization of pERK-immunoreactive cells in trigeminal spinal nucleus caudalis and upper cervical cord following capsaicin injection into oral and craniofacial regions in rats. J Comp Neurol 2008, 507:1428-1440. 10.1002/cne.21620, 18196540.
28. Honda K, Kitagawa J, Sessle BJ, Kondo M, Tsuboi Y, Yonehara Y, Iwata K. Mechanisms involved in an increment of multimodal excitability of medullary and upper cervical dorsal horn neurons following cutaneous capsaicin treatment. Mol Pain 2008, 4:59. 10.1186/1744-8069-4-59, 2661045, 19019214.
29. Yamazaki Y, Ren K, Shimada M, Iwata K. Modulation of paratrigeminal nociceptive neurons following temporomandibular joint inflammation in rats. Exp Neurol 2008, 214:209-218. 10.1016/j.expneurol.2008.08.005, 2684032, 18778706.
30. Dubner R, Bennett GJ. Spinal and trigeminal mechanisms of nociception. Annu Rev Neurosci 1983, 6:381-418. 10.1146/annurev.ne.06.030183.002121, 6132587.
31. Price DD, Hayashi H, Dubner R, Ruda MA. Functional relationships between neurons of marginal and substantia gelatinosa layers of primate dorsal horn. J Neurophysiol 1979, 42:1590-1608.
32. Zhuang ZY, Gerner P, Woolf CJ, Ji RR. ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model. Pain 2005, 114:149-159. 10.1016/j.pain.2004.12.022, 15733640.
33. Morch CD, Hu JW, Arendt-Nielsen L, Sessle BJ. Convergence of cutaneous, musculoskeletal, dural and visceral afferents onto nociceptive neurons in the first cervical dorsal horn. Eur J Neurosci 2007, 26:142-154. 10.1111/j.1460-9568.2007.05608.x, 17614945.
34. Takeda M, Tanimoto T, Ito M, Nasu M, Matsumoto S. Role of capsaicin-sensitive primary afferent inputs from the masseter muscle in the C1 spinal neurons responding to tooth-pulp stimulation in rats. Exp Brain Res 2005, 160:107-117. 10.1007/s00221-004-1990-2, 15289965.
35. Chiang CY, Hu B, Hu JW, Dostrovsky JO, Sessle BJ. Central sensitization of nociceptive neurons in trigeminal subnucleus oralis depends on integrity of subnucleus caudalis. J Neurophysiol 2002, 88:256-264.
36. Iwata K, Tashiro A, Tsuboi Y, Imai T, Sumino R, Morimoto T, Dubner R, Ren K. Medullary dorsal horn neuronal activity in rats with persistent temporomandibular joint and perioral inflammation. J Neurophysiol 1999, 82:1244-1253.
37. Zhang S, Chiang CY, Xie YF, Park SJ, Lu Y, Hu JW, Dostrovsky JO, Sessle BJ. Central sensitization in thalamic nociceptive neurons induced by mustard oil application to rat molar tooth pulp. Neuroscience 2006, 142:833-842. 10.1016/j.neuroscience.2006.06.063, 16934945.
38. Park SJ, Zhang S, Chiang CY, Hu JW, Dostrovsky JO, Sessle BJ. Central sensitization induced in thalamic nociceptive neurons by tooth pulp stimulation is dependent on the functional integrity of trigeminal brainstem subnucleus caudalis but not subnucleus oralis. Brain Res 2006, 1112:134-145. 10.1016/j.brainres.2006.06.115, 16930568.
39. Chiang CY, Wang J, Xie YF, Zhang S, Hu JW, Dostrovsky JO, Sessle BJ. Astroglial glutamate-glutamine shuttle is involved in central sensitization of nociceptive neurons in rat medullary dorsal horn. J Neurosci 2007, 27:9068-9076. 10.1523/JNEUROSCI.2260-07.2007, 17715343.
40. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16:109-110. 10.1016/0304-3959(83)90201-4, 6877845.
41. Iwata K, Fukuoka T, Kondo E, Tsuboi Y, Tashiro A, Noguchi K, Masuda Y, Morimoto T, Kanda K. Plastic changes in nociceptive transmission of the rat spinal cord with advancing age. J Neurophysiol 2002, 87:1086-1093.