Neuropathic pain and neuroplasticity in functional imaging studies;Neuropathische Schmerzsyndrome und Neuroplastizität in der funktionellen Bildgebung

Schmerz

Volumn 24, Issue 2, 2010, Pages 137-145

  Maihofner C ^a   Nickel, F T ^a   Seifert, F ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

FMRI; Functional imaging; MEG; Neuropathic pain; Nociception; Plasticity

Indexed keywords

ACUPUNCTURE; AGNOSIA; ALLODYNIA; BRAIN; CARPAL TUNNEL SYNDROME; COMPLEX REGIONAL PAIN SYNDROME TYPE I; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HYPERALGESIA; MAGNETOENCEPHALOGRAPHY; MOTOR SYSTEM; NERVE CELL PLASTICITY; NERVE DEGENERATION; NEUROIMAGING; NEUROPATHIC PAIN; NEUROTRANSMISSION; NOCICEPTION; NOCICEPTIVE RECEPTOR; PHANTOM PAIN; POSITRON EMISSION TOMOGRAPHY; REVIEW; SENSORY SYSTEM; SOMATOSENSORY CORTEX; TRANSCRANIAL MAGNETIC STIMULATION; TRIGEMINUS NEURALGIA; VOXEL BASED MORPHOMETRY;

BRAIN; BRAIN MAPPING; CARPAL TUNNEL SYNDROME; CEREBRAL CORTEX; CHRONIC DISEASE; COMPLEX REGIONAL PAIN SYNDROMES; DIAGNOSTIC IMAGING; HUMANS; HYPERALGESIA; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE IMAGING; NERVE DEGENERATION; NEURAL INHIBITION; NEURONAL PLASTICITY; NOCICEPTORS; PAIN; PAIN THRESHOLD; PERIPHERAL NERVES; PHANTOM LIMB; RECRUITMENT, NEUROPHYSIOLOGICAL; SPINAL CORD; SYNAPSES;

EID: 77953350602     PISSN: 0932433X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00482-010-0902-6     Document Type: Review

References (80)

1. Amir R, Liu C, Kocsis J et al (2002) Oscillatory mechanism in primary sensory neurones. Brain 125:421-435
2. Amir R, Michaelis M, Devor M (1999) Membrane potential oscillations in dorsal root ganglion neurons: role in normal electrogenesis and neuropathic pain. J Neurosci 19:8589-8596
3. Apkarian AV, Bushnell MC, Treede RD et al (2005) Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain 9:463-484
4. Apkarian AV, Sosa Y, Sonty S et al (2004) Chronic back pain is associated with decreased prefron-tal and thalamic gray matter density. J Neurosci 24:10410-10415
5. Baliki MN, Chialvo DR, Geha PY et al (2006) Chronic pain and the emotional brain: specific brain activity associated with spontaneous fluctuations of intensity of chronic back pain. J Neurosci 26:12165-12173
6. Baron R (2000) Peripheral neuropathic pain: from mechanisms to symptoms. Clin J Pain 16:S12-S20
7. Baron R, Baron Y, Disbrow E et al (1999) Brain processing of capsaicin-induced secondary hyperal-gesia: a functional MRI study. Neurology 53:548-557
8. Baumgartner U, Buchholz HG, Bellosevich A et al (2006) High opiate receptor binding potential in the human lateral pain system. Neuroimage 30:692-699
9. Becerra L, Morris S, Bazes S et al (2006) Trigeminal neuropathic pain alters responses in CNS circuits to mechanical (brush) and thermal (cold and heat) stimuli. J Neurosci 26:10646-10657
10. Birklein F (2002) Mechanism-based treatment principles of neuropathic pain. Fortschr Neurol Psychiatr 70:88-94
11. Borsook D, Moulton EA, Schmidt KF et al (2007) Neuroimaging revolutionizes therapeutic approaches to chronic pain. Mol Pain 3:25
12. Craig AD, Bushnell MC (1994) The thermal grill illusion: unmasking the burn of cold pain. Science 265:252-255
13. Draganski B, Moser T, Lummel N et al (2006) Decrease of thalamic gray matter following limb amputation. Neuroimage 31:951-957
14. Ducreux D, Attal N, Parker F et al (2006) Mechanisms of central neuropathic pain: a combined psy-chophysical and fMRI study in syringomyelia. Brain 129:963-976
15. Dworkin RH (2002) An overview of neuropathic pain: syndromes, symptoms, signs, and several mechanisms. Clin J Pain 18:343-349
16. Elbert T, Flor H, Birbaumer N et al (1994) Extensive reorganization of the somatosensory cortex in adult humans after nervous system injury. Neuro-report 5:2593-2597
17. Flor H (2002) Phantom-limb pain: characteristics, causes, and treatment. Lancet Neurol 1:182-189
18. Flor H, Braun C, Elbert T et al (1997) Extensive reorganization of primary somatosensory cortex in chronic back pain patients. Neurosci Lett 224:5-8
19. Flor H, Denke C, Schaefer M et al (2001) Effect of sensory discrimination training on cortical reorganisation and phantom limb pain. Lancet 357:1763-1764 (Pubitemid 32524209)
20. Flor H, Elbert T, Knecht S et al (1995) Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature 375:482-484
21. Flor H, Nikolajsen L, Staehelin Jensen T (2006) Phantom limb pain: a case of maladaptive CNS plasticity? Nat Rev Neurosci 7:873-881
22. Frettloh J, Huppe M, Maier C (2006) Severity and specificity of neglect-like symptoms in patients with complex regional pain syndrome (CRPS) compared to chronic limb pain of other origins. Pain 124:184-189
23. Freynhagen R, Rolke R, Baron R et al (2008) Pseu-doradicular and radicular low-back pain-a disease continuum rather than different entities? Answers from quantitative sensory testing. Pain 135:65-74
24. Fukui S, Matsuno M, Inubushi T et al (2006) N-Ace-tylaspartate concentrations in the thalami of neuropathic pain patients and healthy comparison subjects measured with (1)H-MRS. Magn Reson Imaging 24:75-79
25. Geha PY, Baliki MN, Harden RN et al (2008) The brain in chronic CRPS pain: abnormal gray-white matter interactions in emotional and autonomic regions. Neuron 60:570-581
26. Grachev ID, Fredrickson BE, Apkarian AV (2000) Abnormal brain chemistry in chronic back pain: an in vivo proton magnetic resonance spectroscopy study. Pain 89:7-18
27. Grachev ID, Thomas PS, Ramachandran TS (2002) Decreased levels of N-acetylaspartate in dorsola-teral prefrontal cortex in a case of intractable severe sympathetically mediated chronic pain (complex regional pain syndrome, type I). Brain Cogn 49:102-113
28. Grusser SM, Diers M, Flor H (2003) Phantom limb pain: aspects of neuroplasticity and intervention. Anasthesiol Intensivmed Notfallmed Schmerzther 38:762-766
29. Harris RE, Clauw DJ, Scott DJ et al (2007) Decreased central mu-opioid receptor availability in fibro-myalgia. J Neurosci 27:10000-10006
30. Hsieh JC, Belfrage M, Stone-Elander S et al (1995) Central representation of chronic ongoing neuropathic pain studied by positron emission tomography. Pain 63:225-236
31. Huse E, Larbig W, Birbaumer N et al (2001) Cortical reorganization and pain. Empirical findings and therapeutic implication using the example of phantom pain. Schmerz 15:131-137
32. Iadarola MJ, Max MB, Berman KF et al (1995) Unilateral decrease in thalamic activity observed with positron emission tomography in patients with chronic neuropathic pain. Pain 63:55-64
33. Jones AK, Kitchen ND, Watabe H et al (1999) Measurement of changes in opioid receptor binding in vivo during trigeminal neuralgic pain using [11C] diprenorphine and positron emission tomography. J Cereb Blood Flow Metab 19:803-808
34. Jones AK, Watabe H, Cunningham VJ et al (2004) Cerebral decreases in opioid receptor binding in patients with central neuropathic pain measured by [11C]diprenorphine binding and PET. Eur J Pain 8:479-485
35. Kuchinad A, Schweinhardt P, Seminowicz DA et al (2007) Accelerated brain gray matter loss in fibro-myalgia patients: premature aging of the brain? J Neurosci 27:4004-4007
36. Kwong KK, Belliveau JW, Chesler DA et al (1992) Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89:5675-5679
37. Lebel A, Becerra L, Wallin D et al (2008) fMRI reveals distinct CNS processing during symptomatic and recovered complex regional pain syndrome in children. Brain 131:1854-1879
38. Lorenz J, Cross D, Minoshima S et al (2002) A unique representation of heat allodynia in the human brain. Neuron 35:383-393
39. Lotze M, Grodd W, Birbaumer N et al (1999) Does use of a myoelectric prosthesis prevent cortical reorganization and phantom limb pain? Nat Neu-rosci 2:501-502
40. Maihofner C, Baron R, Decol R et al (2007) The motor system shows adaptive changes in complex regional pain syndrome. Brain 130:2671-2687
41. Maihofner C, Birklein F (2007) Complex regional pain syndromes: new aspects on pathophysiology and therapy. Fortschr Neurol Psychiatr 75:331-342
42. Maihofner C, Forster C, Birklein F et al (2005) Brain processing during mechanical hyperalgesia in complex regional pain syndrome: a functional MRI study. Pain 114:93-103
43. Maihofner C, Handwerker HO (2005) Differential coding of hyperalgesia in the human brain: a functional MRI study. Neuroimage 28:996-1006
44. Maihofner C, Handwerker HO, Birklein F (2006) Functional imaging of allodynia in complex regional pain syndrome. Neurology 66:711-717
45. Maihofner C, Handwerker HO, Neundorfer B et al (2004) Cortical reorganization during recovery from complex regional pain syndrome. Neurology 63:693-701
46. Maihofner C, Handwerker HO, Neundorfer B et al (2003) Patterns of cortical reorganization in complex regional pain syndrome. Neurology 61:1707-1715
47. Maihofner C, Neundorfer B, Birklein F et al (2006) Mislocalization of tactile stimulation in patients with complex regional pain syndrome. J Neurol 253:772-779 (Pubitemid 43980149)
48. Mcdermott AM, Toelle TR, Rowbotham DJ et al (2006) The burden of neuropathic pain: results from a cross-sectional survey. Eur J Pain 10:127-135
49. Melzack R (1999) From the gate to the neuro-matrix. Pain (Suppl 6):S121-S126
50. Melzack R (2001) Pain and the neuromatrix in the brain. J Dent Educ 65:1378-1382
51. Moisset X, Bouhassira D (2007) Brain imaging of neuropathic pain. Neuroimage 37(Suppl 1):S80-S88
52. Napadow V, Kettner N, Ryan A et al (2006) Soma-tosensory cortical plasticity in carpal tunnel syndrome-a cross-sectional fMRI evaluation. Neuroi-mage 31:520-530
53. Napadow V, Liu J, Li M et al (2007) Somatosensory cortical plasticity in carpal tunnel syndrome treated by acupuncture. Hum Brain Mapp 28:159-171 (Pubitemid 46340072)
54. Nikolajsen L, Ilkjaer S, Kroner K et al (1997) The influence of preamputation pain on postamputation stump and phantom pain. Pain 72:393-405 (Pubitemid 27392856)
55. Ochoa Jl, Yarnitsky D (1994) The triple cold syndrome. Cold hyperalgesia, cold hypoaesthesia and cold skin in peripheral nerve disease. Brain 117(Pt 1):185-197
56. Ogawa S, Lee TM, Kay AR et al (1990) Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci USA 87:9868-9872
57. Pattany PM, Yezierski R P, Widerstrom-Noga EG et al (2002) Proton magnetic resonance spectroscopy of the thalamus in patients with chronic neuropathic pain after spinal cord injury. AJNR Am J Neuro-radiol 23:901-905
58. Petrovic P, Ingvar M, Stone-Elander S et al (1999) A PET activation study of dynamic mechanical al-lodynia in patients with mononeuropathy. Pain 83:459-470
59. Peyron R, Garcia-Larrea L, Gregoire MC et al (1998) Allodynia after lateral-medullary (Wallenberg) in-farct. A PET study. Brain 121(Pt 2):345-356
60. Peyron R, Schneider F, Faillenot I et al (2004) An fMRI study of cortical representation of mechanical allodynia in patients with neuropathic pain. Neurology 63:1838-1846
61. Pleger B, Tegenthoff M, Ragert P et al (2005) Sen-sorimotor retuning corrected in complex regional pain syndrome parallels pain reduction. Ann Neu-rol 57:425-429
62. Ramachandran VS, Stewart M, Rogers-Rama-chandran DC (1992) Perceptual correlates of massive cortical reorganization. Neuroreport 3:583-586
63. Schmidt-Wilcke T, Leinisch E, Ganssbauer S et al (2006) Affective components and intensity of pain correlate with structural differences in gray matter in chronic back pain patients. Pain 125:89-97
64. Schmidt-Wilcke T, Luerding R, Weigand T et al (2007) Striatal grey matter increase in patients suf fering from fibromyalgia-a voxel-based mor-phometry study. Pain 132(Suppl 1):S109-S116
65. Schweinhardt P, Glynn C, Brooks J et al (2006) An fMRI study of cerebral processing of brush-evoked allodynia in neuropathic pain patients. Neuroima-ge 32:256-265
66. Schwenkreis P, Janssen F, Rommel O et al (2003) Bilateral motor cortex disinhibition in complex regional pain syndrome (CRPS) type I of the hand. Neurology 61:515-519
67. Seifert F, Jungfer I, Schmelz M et al (2008) Representation of UV-B-induced thermal and mechanical hyperalgesia in the human brain: a functional MRI study. Hum Brain Mapp 29:1337-1342
68. Seifert F, Maihofner C (2007) Representation of cold allodynia in the human brain-a functional MRI study. Neuroimage 35:1168-1180
69. Sprenger T, Henriksen G, Valet M et al (2007) Positron emission tomography in pain research. From the structure to the activity of the opiate receptor system. Schmerz 21:503-513
70. Tecchio F, Padua L, Aprile I et al (2002) Carpal tunnel syndrome modifies sensory hand cortical so-matotopy: a MEG study. Hum Brain Mapp 17:28-36
71. Tolle TR, Baron R (2002) Neuropathic pain. Basic principles for successful therapy. MMW Fortschr Med 144:41-44
72. Tracey I, Mantyh PW (2007) The cerebral signature for pain perception and its modulation. Neuron 55:377-391
73. Treede RD, Kenshalo DR, Gracely RH et al (1999) The cortical representation of pain. Pain 79:105-111
74. Willoch F, Schindler F, Wester HJ et al (2004) Central poststroke pain and reduced opioid receptor binding within pain processing circuitries: a [11C]diprenorphine PET study. Pain 108:213-220
75. Willoch F, Tolle TR, Wester HJ et al (1999) Central pain after pontine infarction is associated with changes in opioid receptor binding: a PET study with 11C-diprenorphine. AJNR Am J Neuroradiol 20:686-690
76. Witting N, Kupers RC, Svensson P et al (2001) Experimental brush-evoked allodynia activates posterior parietal cortex. Neurology 57:1817-1824
77. Witting N, Kupers RC, Svensson P et al (2006) A PET activation study of brush-evoked allodynia in patients with nerve injury pain. Pain 120:145-154
78. Woolf CJ, Mannion RJ (1999) Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet 353:1959-1964
79. Yang T T, Gallen CC, Ramachandran VS et al (1994) Noninvasive detection of cerebral plasticity in adult human somatosensory cortex. Neuroreport 5:701-704
80. Zambreanu L, Wise RG, Brooks JC et al (2005) A role for the brainstem in central sensitisation in humans. Evidence from functional magnetic resonance imaging. Pain 114:397-407