Formulation and evaluation of compression coated piroxicam tablets for colon specific drug delivery

Acta Pharmaceutica Sciencia

Volumn 52, Issue 3, 2010, Pages 281-294

  Veerareddy, Prabhakar Reddy ^a   Manthri, Rajendra Prasad ^a  

^a ST PETER'S INSTITUTE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Colonic drug delivery; Guar gum; Piroxicam; Rat caecal contents

Indexed keywords

GUAR GUM; HYDROXYPROPYLMETHYLCELLULOSE; PIROXICAM; POLYMER;

ADULT; ARTICLE; CECUM; COLON; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; DRUG STABILITY; DRUG TRANSPORT; HUMAN; HUMAN EXPERIMENT; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NORMAL HUMAN; RAT; TABLET COMPRESSION; TABLET FORMULATION; TABLET FRIABILITY; TABLET HARDNESS;

EID: 79751513681     PISSN: 13072080     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Ashford, M., Fell, J., Attwood, D., Sharma, H. and Woodhead, P. (1993). An evaluation of pectin as a carrier for drug targeting to the colon. J. Control. Rel. 26: 213-220.
2. Ashford, M., Fell, J., Attwood, D., Sharma, H. and Woodhead, P. (1994). Studies on pectin formulations for colonic drug delivery. J. Control. Rel. 30: 225-232.
3. Chourasia, M.K. and Jain, S.K. (2003). Pharmaceutical approaches to colon targeted drug delivery systems. Eur. J. Pharm. Sci. 6:32-66.
4. Demiroz, F. T., Acarturk, F., Takka, S. and Boyunaga, O. K. (2004). In-vitro and In-vivo evaluation of mesalazine-guar gum matrix tablets for colonic drug delivery. J. Drug Target. 12: 105-112.
5. Fujino, S., Hiwatashi, N., Sato, K., Imai, H., Akazawa, T. and Ogawa, K. (1995). Socioeconomic evaluations on drug treatment for inflammatory bowel disease (IBD):/Effect of a controlled-release mesalazine tablet (N-5ASA). Rinshoiyaku 11: 1357-1380.
6. Hovgaard, L. and Brøndsted, H. (1995). Dextran hydrogels for colon-specific drug delivery, J. Control. Rel. 36: 159-166.
7. Kenyon, C. J., Nardi, R. V., Wong, D., Hooper, G., Wilding I.R. and Friend, D.R. (1997). Colonic delivery of dexamethasone: a pharmacoscintigraphic evaluation. Aliment. Pharmacol. Ther. 11: 205-213.
8. Krishnaiah, Y. S. R., Satyanarayana, V. and Rama Prasad, Y. V. (1999). Studies of guar gum compression-coated 5-aminosalicylic acid tablets for colon-specific drug delivery. Drug Dev. Ind. Pharm. 25: 651-657.
9. Krishnaiah, Y. S. R., Satyanarayana, V., Dinesh Kumar, B., Karthikeyan, R. S. and Bhaskar, P. (2003a). In vivo pharmacokinetics in human volunteers: oral administered guar gum-based colon targeted 5-fluorouracil tablets. Eur. J. Pharm. Sci. 19: 355-362.
10. Krishnaiah, Y. S. R., Reddy, B., Satyanarayana, V. and Karthikeyan, R. S. (2002a). Studies on the development of oral colon targeted drug delivery systems for metronidazole in the treatment of amoebiasis. Int. J. Pharm. 236: 43-55.
11. Krishnaiah, Y. S. R., Satyanarayana, S., Rama Prasad, Y. V. and Rao, S. N. (1998b). Evaluation of guar gum as a compression coat for drug targeting to colon. Int. J. Pharm. 171: 137-146.
12. Krishnaiah, Y. S. R., Satyanarayana, V., Dinesh Kumar, B. and Karthikeyan, R. S. (2002). In vitro drug release studies on guar gum-based colon targeted oral drug delivery systems of 5-fluorouracil. Eur. J. Pharm. Sci. 16: 185-192.
13. Krishnaiah, Y. S. R., Satyanarayana, V., Dinesh Kumar, B. and Karthikeyan, R. S. (2002b). Studies on the development of colon targeted delivery systems for celecoxib in the prevention of colorectal cancer. J. Drug Target. 10: 247-254.
14. Krishnaiah, Y. S. R., Satyanarayana, V., Rama Prasad, Y. V. and Rao, S.N. (1998a). Gamma scintigraphic studies on guar gum matrix tablets for colonic drug delivery in healthy volunteers. J. Control. Rel. 55: 245-252.
15. Krishnaiah, Y. S. R., Veer Raju, P., Dinesh Kumar, B., Satyanarayana, V., Karthikeyan, R. S. and Bashkar, P. (2003b). Pharmacokinetic evaluation of guar gum-based colon-targeted drug delivery systems of mebendazole in healthy volunteers. J. Control. Rel. 88: 95-103.
16. Krishnaiah, Y.S.R., Indira Muzib, Y., Srinivasa Rao, G., Bashkar, P. and Satyanarayana, V. (2002c). Design and in vitro evaluation of oral colon targeted drug delivery systems for tinidazole. J. Drug Target. 10: 579-584.
17. Leopold, C.S. (1999). Coated dosage forms for colon-specific drug delivery. Pharm Sci Technolo Today 2: 197-204.
18. Milojevic, S., Newton, J. M. and Cummings. (1995). Amylase, the new perspective in oral drug delivery to the human large intestine. Stp Pharma Sci. 5: 47-53.
19. Munjeri, O., Collett, J. H. and Fell, J.T. (1997). Hydrogel beads based on amidated pectins for colon-specific drug delivery: role of chitosan in modifying drug release, J. Control. Rel. 46: 272-278.
20. Peppas, N.A. (1985). Analysis of Fickian and non-Fickian drug release from polymers. Pharm. Acta Helv. 60: 110-111.
21. Rama Prasad, Y. V., Krishnaiah, Y. S. R. and Satyanarayana, S. (1998). In vitro evaluation of guar gum as a carrier for colon-specific drug delivery. J. Control. Rel. 51: 281-287.
22. Rubinstein, A., Nakar, D. and Sintov, A. (1992b). Chondroitin sulfate: a potential biodegradable carrier for colon-specific drug delivery. Int. J. Pharm. 84: 141-150.
23. Rubinstein, A., Nakar, D. and Sintov, A. (1992a). A colonic drug delivery: enhanced release of indomethacin from cross-linked chondroitin matrix in rat caecal content, Pharm. Res. 9 276-278.
24. Rubinstein, A., Radai, R., Ezra, M., Pathak, S. and Rokem, J. S. (1993). In vitro evaluation of calcium pectinate: a potential colon-specific drug delivery carrie. Pharm. Res. 10: 258-263.
25. Sinha, V.R. and Kumria, R. (2001). Polysaccharides in colon-specific drug delivery, Int. J. Pharm. 224: 19-38.
26. Sinha, V.R. and Kumria, R. (2003). Microbially triggered drug delivery to the colon. Eur. J. Pharm. Sci. 18: 3-18.
27. Tozaki, H., Komoike, J., Tada, C., Maruyama, T., Terabe, A., Suzuki, T., Yamamoto, A. and Muranishi, S. (1997). Chitosan capsules for colon- specific drug delivery: improvement of insulin absorption from the rat colon. J. Pharm. Sci. 86: 1016-1021.
28. Wakerly, Z., Fell, J. T., Attwood, D. and Parkins, D.A. (1996a). In vitro evaluation of pectin-based colonic drug delivery systems. Int. J. Pharm. 129: 73-77.
29. Wakerly, Z., Fell, J. T., Attwood, D. and Parkins, D.A. (1996b). Pectin/ethyl cellulose film coating formulations for colonic drug delivery. Pharm. Res. 13: 1210-1212.
30. Yang, L., Chu, J.S., and Fix, J.A. (2002). Colon-specific drug delivery: new approaches and in-vitro in-vivo evaluation. Int. J. Pharm. 235: 1-15.