Pectin/ethylcellulose film coating formulations for colonic drug delivery

Pharmaceutical Research

Volumn 13, Issue 8, 1996, Pages 1210-1212

  Wakerly, Z ^a   Fell, J T ^a   Attwood, D ^a   Parkins, D ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Colonic delivery; Enzymic degradation; Ethylcellulose; Film coating; Pectin

Indexed keywords

ETHYL CELLULOSE; PARACETAMOL; PECTIN; UNCLASSIFIED DRUG;

ARTICLE; DISSOLUTION; DRUG ANALYSIS; DRUG COATING; DRUG COMPARISON; DRUG DELIVERY SYSTEM; DRUG DOSE; DRUG RELEASE; IN VITRO STUDY; NONHUMAN; PH; PRIORITY JOURNAL; STORAGE;

CELLULOSE; COLON; PECTINS; VEHICLES;

EID: 0029781749     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016016404404     Document Type: Article

References (5)

1. M. Ashford, J. Fell, D. Attwood, H. Sharma and P. Woodhead. An evaluation of pectin as a carrier for drug targeting to the colon. J. Control. Rel. 26:213-220 (1993).
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3. C. R. Steuernagel. Latex emulsions for controlled delivery in J. W. McGinity (Ed), Aqueous polymeric coatings for pharmaceutical dosage forms, Marcel Dekker, New York pp 1-61.
4. R. Bodmeier and O. Paeratakul. Process and formulation variables affecting the drug release from chlorpheniramine maleate loaded beads coated with commercial and self prepared aqueous ethylcellulose pseudolatexes. Int. J. Pharm. 70:59-68 (1991).
5. A. Rubinstein, R. Radai, M. Ezra, S. Pathak and J. S. Rokem. In vitro evaluation of calcium pectinate: a potential colon-specific drug delivery carrier. Pharm. Res. 10:258-263 (1993).