Favourable prognostic value of antibodies anti-HSP20 in patients with cystic echinococcosis: A differential immunoproteomic approach

Parasite Immunology

Volumn 33, Issue 3, 2011, Pages 193-198

  Vacirca, D ^a   Perdicchio, M ^a   Campisi, E ^a   Delunardo, F ^a   Ortona, E ^a   Margutti, P ^a   Teggi, A ^b   Gottstein, B ^c   Siracusano, A ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Echinococcus granulosus; Follow up; Heat shock protein 20; Immunological marker; Proteomics

Indexed keywords

ALBENDAZOLE; BIOLOGICAL MARKER; HEAT SHOCK PROTEIN 20; HEAT SHOCK PROTEIN 20 ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANTIBODY BLOOD LEVEL; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE COURSE; ECHINOCOCCOSIS; FEMALE; FOLLOW UP; HUMAN; IMMUNOBLOTTING; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; MULTIPLE CYCLE TREATMENT; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; PROTEOMICS; SCHOOL CHILD; TREATMENT DURATION; TWO DIMENSIONAL GEL ELECTROPHORESIS; VALIDATION STUDY;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; BIOLOGICAL MARKERS; ECHINOCOCCOSIS; ECHINOCOCCUS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; HSP20 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOBLOTTING; MALE; PROGNOSIS; PROTEOME;

ECHINOCOCCUS GRANULOSUS; OVIS ARIES;

EID: 79751482640     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2010.01264.x     Document Type: Article

References (24)

1. Budke CM, Deplazes P & Torgerson PR. Global socioeconomic impact of cystic echinococcosis. Emerg Infect Dis 2006; 12: 296-303.
2. Craig PS, McManus DP, Lightowlers MW, et al. Prevention and control of cystic echinococcosis. Lancet Infect Dis 2007; 7: 385-394.
3. Siracusano A, Teggi A & Ortona E. Human cystic echinococcosis: old problems and new perspectives. Interdiscip Perspect Infect Dis. 2009; 2009: 1-7.
4. Zhang W, Ross AG & McManus DP. Mechanisms of immunity in hydatid disease: implications for vaccine development. J Immunol 2008; 181: 679-685.
5. Carmena D, Benito A & Eraso E. Antigens for the immunodiagnosis of Echinococcus granulosus infection: an update. Acta Trop 2006; 98: 74-86.
6. Daeki AO, Craig PS & Shambesh MK. IgG-subclass antibody responses and the natural history of hepatic cystic echinococcosis in asymptomatic patients. Ann Trop Med Parasitol 2000; 94: 319-328.
7. Rogan MT, Hai WY, Richardson R, et al. Hydatid cysts: does every picture tell a story? Trends Parasitol 2006; 22: 431-438.
8. Junghanss T, da Silva AM, Horton J, et al. Clinical management of cystic echinococcosis: state of the art, problems, and perspectives. Am J Trop Med Hyg 2008; 79: 301-311.
9. Ben Nouir N, Nuñez S, Gianinazzi C, et al. Assessment of Echinococcus granulosus somatic protoscolex antigens for serological follow-up of young patients surgically treated for cystic echinococcosis. J Clin Microbiol 2008; 46: 1631-1640.
10. Chemale G, van Rossum AJ, Jefferies JR, et al. Proteomic analysis of the larval stage of the parasite Echinococcus granulosus: causative agent of cystic hydatid disease. Proteomics 2003; 3: 1633-1636.
11. Monteiro KM, de Carvalho MO, Zaha A & Ferreira HB. Proteomic analysis of the Echinococcus granulosus metacestode during infection of its intermediate host. Proteomics 2010; 10: 1985-1999.
12. Vacirca D, Delunardo F, Matarrese P, et al. Autoantibodies to the adenosine triphosphate synthase play a pathogenetic role in Alzheimer's disease. Neurobiol Aging 2010; Jun 29. [Epub ahead of print.]
13. Delunardo F, Ortona E, Margutti P, et al. Identification of a novel 19kDa Echinococcus granulosus antigen. Acta Trop 2010; 113: 42-47.
14. Haslbeck M, Franzmann T, Weinfurtner D & Buchner J. Some like it hot: the structure and function of small heat-shock proteins. Nat Struct Mol Biol 2005; 12: 842-846.
15. Ortona E, Margutti P, Delunardo F, et al. Molecular and immunological characterization of the C-terminal region of a new Echinococcus granulosus Heat Shock Protein 70. Parasite Immunol 2003; 25: 119-126.
16. Wang Y, Cheng Z, Lu X & Tang C. Echinococcus multilocularis: proteomic analysis of the protoscoleces by two-dimensional electrophoresis and mass spectrometry. Exp Parasitol 2009; 123: 162-167.
17. Franchi C, Di Vico B & Teggi A. Long-term evaluation of patients with hydatidosis treated with benzimidazole carbamates. Clin Infect Dis 1999; 29: 304-309.
18. Brunetti E & Junghanss T. Update on cystic hydatid disease. Curr Opin Infect Dis 2009; 22: 497-502.
19. Riganò R, Ioppolo S, Ortona E, et al. Long-term serological evaluation of patients with cystic echinococcosis treated with benzimidazole carbamates. Clin Exp Immunol 2002; 129: 485-492.
20. Ben Nouir N, Gianinazzi C, Gorcii M, et al. Isolation and molecular characterization of recombinant Echinococcus granulosus P29 protein (recP29) and its assessment for the post-surgical serological follow-up of human cystic echinococcosis in young patients. Trans Roy Soc Trop Med. Hyg 2009; 103: 355-364.
21. Hernández-González A, Muro A, Barrera I, et al. Usefulness of four different Echinococcus granulosus recombinant antigens for serodiagnosis of unilocular hydatid disease (UHD) and postsurgical follow-up of patients treated for UHD. Clin Vaccine Immunol. 2008; 15: 147-153.
22. Ortona E, Margutti P, Delunardo F, et al. Screening of an Echinococcus granulosus cDNA library with IgG4 from patients with cystic echinococcosis identifies a new tegumental protein involved in the immune escape. Clin Exp Immunol 2005; 142: 528-538.
23. World Health Organization Informal Working Group. International classification of ultrasound images in cystic echinococcosis for application in clinical and field epidemiological settings. Acta Trop 2003; 85: 253-261.
24. Informal Working Group on Echinococcosis. Guidelines for treatment of cystic and alveolar echinococcosis in humans. Bull World Health Organ 1996; 74: 231-242.