Identification of a novel 19 kDa Echinococcus granulosus antigen

Acta Tropica

Volumn 113, Issue 1, 2010, Pages 42-47

  Delunardo, Federica ^a   Ortona, Elena ^a   Margutti, Paola ^a   Perdicchio, Maurizio ^a   Vacirca, Davide ^a   Teggi, Antonella ^b   Sorice, Maurizio ^c   Siracusano, Alessandra ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

cDNA library; Echinococcus granulosus; Follow up; Host parasite relationship

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENTARY DNA; EG PROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G4; PARASITE ANTIGEN; PROTEIN; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN; CYST; DISEASE; DNA; HOST-PARASITE INTERACTION; PROTEIN;

ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DNA LIBRARY; ECHINOCOCCOSIS; ECHINOCOCCUS GRANULOSUS; ENZYME LINKED IMMUNOSORBENT ASSAY; FOLLOW UP; HUMAN; IMMUNOBLOTTING; IMMUNOGLOBULIN BLOOD LEVEL; LIVER HYDATID CYST; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; SCREENING;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; BIOLOGICAL MARKERS; ECHINOCOCCOSIS; ECHINOCOCCUS GRANULOSUS; GENE LIBRARY; HELMINTH PROTEINS; HUMANS; IMMUNOGLOBULIN G; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT;

ECHINOCOCCUS GRANULOSUS;

EID: 71549159745     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actatropica.2009.09.003     Document Type: Article

References (17)

1. Craig P.S., McManus D.P., Lightowlers M.W., Chabalgoity J.A., Garcia H.H., Gavidia C.M., Gilman R.H., Gonzalez A.E., Lorca M., Naquira C., Nieto A., and Schantz P.M. Prevention and control of cystic echinococcosis. Lancet Infect. Dis. 7 (2007) 385-394
2. Craig P.S. Immunodiagnosis of Echinococcus granulosus and a comparison of techniques for diagnosis of canine echinococcosis. In: Andersen F.L., Ouhelli H., and Kachani M. (Eds). Compendium on Cystic Echinococcosis (1997), Brigham Young University: Print Services, Provo, UT, USA 85-118
3. Daeki A.O., Craig P.S., and Shambesh M.K. IgG-subclass antibody responses and the natural history of hepatic cystic echinococcosis in asymptomatic patients. Ann. Trop. Med. Parasitol. 94 (2000) 319-328
4. Garraud O., Perraut R., Riveau G., and Nutman T.B. Class and subclass selection in parasite-specific antibody responses. Trends Parasitol. 19 (2003) 300-304
5. Informal Working Group on Echinococcosis. Guidelines for treatment of cystic and alveolar echinococcosis in humans. Bull. World Health Organ. 74 (1996) 231-241
6. Lightowlers M.W. Cestode vaccines: origins, current status and future prospects. Parasitology 133 Suppl. (2006) S27-S42
7. Margutti P., Ortona E., Vaccari S., Barca S., Riganò R., Teggi A., Muhschlegel F., Frosch M., and Siracusano A. Cloning and expression of a cDNA encoding an elongation factor 1beta/delta protein from Echinococcus granulosus with immunogenic activity. Parasite Immunol. 21 (1999) 485-492
8. Margutti P., Ortona E., Delunardo F., Tagliani A., Profumo E., Riganò R., Buttari B., Teggi A., and Siracusano A. Thioredoxin peroxidase from Echinococcus granulosus: a candidate to extend the antigenic panel for the immunodiagnosis of human cystic echinococcosis. Diagn. Microbiol. Infect. Dis. 60 (2008) 279-285
9. Ortona E., Margutti P., Vaccari S., Riganò R., Profumo E., Buttari B., Chersi A., Teggi A., and Siracusano A. Elongation factor 1 beta/delta of Echinococcus granulosus and allergic manifestations in human cystic echinococcosis. Clin. Exp. Immunol. 125 (2001) 110-116
10. Ortona E., Margutti P., Delunardo F., Nobili V., Profumo E., Riganò R., Buttari B., Carulli G., Azzarà A., Teggi A., Bruschi F., and Siracusano A. Screening of an Echinococcus granulosus cDNA library with IgG4 from patients with cystic echinococcosis identifies a new tegumental protein involved in the immune escape. Clin. Exp. Immunol. 142 (2005) 528-538
11. Pawlowski Z.S., Eckert J., Vuitton D.A., Ammann R.W., Kern P., Craig P.S., Dar K.F., De Rosa F., Filice C., Gottstein B., Grimm F., Macpherson C.N.L., Sato N., Todorov T., Uchino J., von Sinner W., and Wen H. Echinococcosis in humans: clinical aspects, diagnosis and treatment. In: Eckert J., Gemmel M.A., Meslin F.X., and Pawlowski Z.S. (Eds). Manual on Echinococcosis in Humans and Animals: A Zoonosis of Global Concern (2001), WHO/OIE 20-66
12. Rafiei A., and Craig P.S. The immunodiagnostic potential of protoscolex antigens in human cystic echinococcosis and the possible influence of parasite strain. Ann. Trop. Med. Parasitol. 96 (2002) 383-389
13. Rickard M.D., and Williams J.F. Hydatidosis/Cysticercosis: Immune mechanisms and immunization against infection. Adv. Parasitol. 21 (1982) 229-295
14. Riganò R., Ioppolo S., Ortona E., Margutti P., Profumo E., Ali M.D., Di Vico B., Teggi A., and Siracusano A. Long-term serological evaluation of patients with cystic echinococcosis treated with benzimidazole carbamates. Clin. Exp. Immunol. 129 (2002) 485-492
15. Rogan M.T., Hai W.Y., Richardson R., Zeyhle E., and Craig P.S. Hydatid cysts: does every picture tell a story?. Trends Parasitol. 22 (2006) 431-438
16. Siracusano A., Riganò R., Ortona E., Profumo E., Margutti P., Buttari B., Delunardo F., and Teggi A. Immunomodulatory mechanisms during Echinococcus granulosus infection. Exp. Parasitol. 119 (2008) 483-489
17. Zhang W., Ross A.G., and McManus D.P. Mechanisms of immunity in hydatid disease: implications for vaccine development. J. Immunol. 181 (2008) 6679-6685