Review: CADASIL and migraine: A narrative review

Cephalalgia

Volumn 30, Issue 11, 2010, Pages 1284-1289

  Liem, Michael K ^a   Lesnik Oberstein, Saskia Aj ^a   Van Der Grond, Jeroen ^a   Ferrari, Michel D ^a   Haan, Joost ^a,b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RIJNLAND HOSPITAL   (Netherlands)

Author keywords

aura; CADASIL; Migraine; NOTCH3; spreading depression

Indexed keywords

CADASIL; HUMAN; MEDLINE; MIGRAINE; MIGRAINE AURA; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; REVIEW; DISEASE PREDISPOSITION; GENETICS;

NOTCH RECEPTOR; NOTCH3 PROTEIN, HUMAN;

CADASIL; DISEASE SUSCEPTIBILITY; HUMANS; MIGRAINE DISORDERS; RECEPTORS, NOTCH;

EID: 79751478770     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1177/0333102410370870     Document Type: Review

References (62)

1. Launer LJ, Terwindt GM, Ferrari MD The prevalence and characteristics of migraine in a population-based cohort: (Pubitemid 29382048)
2. Goadsby PJ, Lipton RB, Ferrari MD Drug therapy: migraine-current understanding and treatment. N Engl J Med 2002 ; 346: 257-270. (Pubitemid 34438866)
3. Goadsby PJ The vascular theory of migraine - a great story wrecked by the facts. Brain 2009 ; 132: 6-7.
4. Lauritzen M. Pathophysiology of the migraine aura: the spreading depression theory. Brain 1994 ; 117 (Pt. 1). 199-210. (Pubitemid 24103394)
5. Hadjikhani N., Sanchez Del RM, Wu O., et al. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci USA 2001 ; 98: 4687-4692. (Pubitemid 32295037)
6. Stam AH, Haan J., van den Maagdenberg AM, Ferrari MD, Terwindt GM Migraine and genetic and acquired vasculopathies. Cephalalgia 2009 ; 29: 1006-1117.
7. Brennan KC, Beltran-Parrazal L., Lopez-Valdes HE, Theriot J., Toga AW, Charles AC Distinct vascular conduction with cortical spreading depression. J Neurophysiol 2007 ; 97: 4143-4151. (Pubitemid 47080646)
8. Dreier JP, Kleeberg J., Petzold G., et al. Endothelin-1 potently induces Leao's cortical spreading depression in vivo in the rat: a model for an endothelial trigger of migrainous aura? Brain 2002 ; 125: 102-112. (Pubitemid 34084040)
9. Dichgans M., Mayer M., Uttner I., et al. The phenotypic spectrum of CADASIL: clinical findings in 102 cases. Ann Neurol 1998 ; 44: 731-739. (Pubitemid 28516043)
10. Joutel A., Vahedi K., Corpechot C., et al. Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients. Lancet 1997 ; 350: 1511-1515. (Pubitemid 28036555)
11. Ruchoux MM, Guerouaou D., Vandenhaute B., Pruvo JP, Vermersch P., Leys D. Systemic vascular smooth muscle cell impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Acta Neuropathol (Berl) 1995 ; 89: 500-512.
12. Oberstein SA, van den Boom R., Van Buchem MA, et al. Cerebral microbleeds in CADASIL. Neurology 2001 ; 57: 1066-1070. (Pubitemid 32880204)
13. van den Boom R., Lesnik Oberstein SA, Ferrari MD, Haan J., Van Buchem MA Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: MR imaging findings at different ages-3rd-6th decades. Radiology 2003 ; 229: 683-690. (Pubitemid 37467569)
14. Liem MK, van der Grond J., Haan J., et al. Lacunar infarcts are the main correlate with cognitive dysfunction in CADASIL. Stroke 2007 ; 38: 923-928. (Pubitemid 46568454)
15. Chabriat H., Levy C., Taillia H., et al. Patterns of MRI lesions in CADASIL. Neurology 1998 ; 51: 452-457. (Pubitemid 28406321)
16. Jung HH, Bassetti C., Tournier-Lasserve E., et al. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: a clinicopathological and genetic study of a Swiss family. J Neurol Neurosurg Psychiatry 1995 ; 59: 138-143.
17. Rufa A., Dotti MT, Franchi M., et al. Systemic blood pressure profile in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Stroke 2005 ; 36: 2554-2558.
18. Singhal S., Bevan S., Barrick T., Rich P., Markus HS The influence of genetic and cardiovascular risk factors on the CADASIL phenotype. Brain 2004 ; 127: 2031-2038. (Pubitemid 39150261)
19. Kim Y., Choi EJ, Choi CG, et al. Characteristics of CADASIL in Korea: a novel cysteine-sparing Notch3 mutation. Neurology 2006 ; 66: 1511-1516. (Pubitemid 43958545)
20. Lee YC, Yang AH, Liu HC, et al. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: two novel mutations in the NOTCH3 gene in Chinese. J Neurol Sci 2006 ; 246: 111-115.
21. Lv H., Yao S., Zhang W., et al. [Clinical features in 4 Chinese families with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)]. Beijing Da Xue Xue Bao 2004 ; 36: 496-500.
22. Uchino M., Hirano T., Uyama E., Hashimoto Y. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and CADASIL-like disorders in Japan. Ann NY Acad Sci 2002 ; 977: 273-278. (Pubitemid 35418164)
23. Vahedi K., Chabriat H., Levy C., Joutel A., Tournier-Lasserve E., Bousser MG Migraine with aura and brain magnetic resonance imaging abnormalities in patients with CADASIL. Arch Neurol 2004 ; 61: 1237-1240. (Pubitemid 39062677)
24. Verin M., Rolland Y., Landgraf F., et al. New phenotype of the cerebral autosomal dominant arteriopathy mapped to chromosome 19: migraine as the prominent clinical feature. J Neurol Neurosurg Psychiatry 1995 ; 59: 579-585.
25. Ceroni M., Poloni TE, Tonietti S., et al. Migraine with aura and white matter abnormalities: Notch3 mutation. Neurology 2000 ; 54: 1869-1871. (Pubitemid 30428424)
26. van den Boom R., Lesnik Oberstein SA, Spilt A., et al. Cerebral hemodynamics and white matter hyperintensities in CADASIL. J Cereb Blood Flow Metab 2003 ; 23: 599-604. (Pubitemid 36566136)
27. Chabriat H., Pappata S., Ostergaard L., et al. Cerebral hemodynamics in CADASIL before and after acetazolamide challenge assessed with MRI bolus tracking. Stroke 2000 ; 31: 1904-1912. (Pubitemid 30620471)
28. Tfelt-Hansen P., Thorbjorn JL, Olesen J. Delayed hyper-perfusion following migraine with a prolonged aphasic aura in a patient with CADASIL. Cephalalgia 2008 ; 28: 899-902.
29. Leonardi M., Steiner TJ, Scher AT, Lipton RB The global burden of migraine: measuring disability in headache disorders with WHO's Classification of Functioning, Disability and Health (ICF). J Headache Pain 2005 ; 6: 429-440. (Pubitemid 43078769)
30. Piper RD, Lambert GA, Duckworth JW Cortical blood-flow changes during spreading depression in cats. Am J Physiol 1991 ; 261: H96-H102.
31. Andersen AR, Friberg L., Olsen TS, Olesen J. Delayed hyperemia following hypoperfusion in classic migraine. Single photon emission computed tomographic demonstration. Arch Neurol 1988 ; 45: 154-159. (Pubitemid 18054530)
32. Sukhotinsky I., Dilekoz E., Moskowitz MA, Ayata C. Hypoxia and hypotension transform the blood flow response to cortical spreading depression from hyperemia into hypoperfusion in the rat. J Cereb Blood Flow Metab 2008 ; 28: 1369-1376. (Pubitemid 351896654)
33. Olesen J., Friberg L., Olsen TS, et al. Timing and topography of cerebral blood-flow, aura, and headache during migraine attacks. Ann Neurol 1990 ; 28: 791-798.
34. Sanchez-Del-Rio M., Reuter U., Moskowitz MA New insights into migraine pathophysiology. Curr Opin Neurol 2006 ; 19: 294-298. (Pubitemid 43804686)
35. Wolthausen J., Sternberg S., Gerloff C., May A. Are cortical spreading depression and headache in migraine causally linked? Cephalalgia 2009 ; 29: 244-249.
36. Kunkler PE, Kraig RP Hippocampal spreading depression bilaterally activates the caudal trigeminal nucleus in rodents. Hippocampus 2003 ; 13: 835-844. (Pubitemid 37407970)
37. Welch KM Brain hyperexcitability: the basis for antiepileptic drugs in migraine prevention. Headache 2005 ; 45: S25-S32.
38. Arboleda-Velasquez JF, Zhou Z., Shin HK, et al. Linking Notch signaling to ischemic stroke. Proc Natl Acad Sci USA 2008 ; 105: 4856-4861. (Pubitemid 351753836)
39. Eikermann-Haerter K., Wang Y., Dilekoz E., et al. Increased susceptibility to cortical spreading depression in cadasil mutant mice. J Cereb Blood Flow Metabolism 2009 ; 29: S53.
40. Dalkara T., Nozari A., Moskowitz MA Migraine aura pathophysiology: the role of blood vessels and microembolisation. Lancet Neurol 2010 ; 9: 309-317.
41. Moore CI, Cao R. The hemo-neural hypothesis: on the role of blood flow in information processing. J Neurophysiol 2008 ; 99: 2035-2047.
42. Nozari A., Dilekoz E., Sukhotinsky I., et al. Microemboli may link spreading depression migraine aura and patent foramen ovale. Ann Neurol 2010 ; 67 (2). 221-229.
43. Bahra A., Matharu MS, Buchel C., Frackowiak RS, Goadsby PJ Brainstem activation specific to migraine headache. Lancet 2001 ; 357: 1016-1017. (Pubitemid 32285399)
44. Weiller C., May A., Limmroth V., et al. Brain-system activation in spontaneous human migraine attacks. Nature Med 1995 ; 1: 658-660.
45. Cao Y., Aurora SK, Nagesh V., Patel SC, Welch KM Functional MRI-BOLD of brainstem structures during visually triggered migraine. Neurology 2002 ; 59: 72-78. (Pubitemid 34742797)
46. Welch KM, Cao Y., Aurora S., Wiggins G., Vikingstad EM MRI of the occipital cortex, red nucleus, and substantia nigra during visual aura of migraine. Neurology 1998 ; 51: 1465-1469. (Pubitemid 28520581)
47. Rocca MA, Ceccarelli A., Falini A., et al. Brain gray matter changes in migraine patients with T2-visible lesions: a 3-T MRI study. Stroke 2006 ; 37: 1765-1770. (Pubitemid 44297727)
48. Goadsby PJ Neurovascular headache and a mid-brain vascular malformation: evidence for a role of the brainstem in chronic migraine. Cephalalgia 2002 ; 22: 107-111. (Pubitemid 34494130)
49. Obermann M., Gizewski ER, Limmroth V., Diener HC, Katsarava Z. Symptomatic migraine and pontine vascular malformation: evidence for a key role of the brainstem in the pathophysiology of chronic migraine. Cephalalgia 2006 ; 26: 763-766.
50. Kruit MC, Launer LJ, Ferrari MD, Van Buchem MA Brain stem and cerebellar hyperintense lesions in migraine. Stroke 2006 ; 37: 1109-1112.
51. Chabriat H., Pappata S., Poupon C., et al. Clinical severity in CADASIL related to ultrastructural damage in white matter: in vivo study with diffusion tensor MRI. Stroke 1999 ; 30: 2637-2643.
52. Kors EE, Vanmolkot KRJ, Haan J., Frants RR, van den Maagdenberg AM, Ferrari MD Recent findings in headache genetics. Curr Opinion Neurology 2004 ; 17: 283-288. (Pubitemid 38720980)
53. Russell MB, Olesen J. Increased familial risk and evidence of genetic-factor in migraine. BMJ 1995 ; 311: 541-544.
54. Mulder EJ, van Baal C., Gaistz D., et al. Genetic and environmental influences on migraine: a twin study across six countries. Twin Res 2003 ; 6: 422-431. (Pubitemid 38019780)
55. Schwaag S., Evers S., Schirmacher A., Stogbauer F., Ringelstein EB, Kuhlenbaumer G. Genetic variants of the NOTCH3 gene in migraine - a mutation analysis and association study. Cephalalgia 2006 ; 26: 158-161.
56. Borroni B., Brambilla C., Liberini P., et al. Investigating the association between Notch3 polymorphism and migraine. Headache 2006 ; 46: 317-321.
57. Bohlega S., Al SA, Edris A., et al. CADASIL in Arabs: clinical and genetic findings. BMC Med Genet 2007 ; 8: 67.
58. Uyguner ZO, Siva A., Kayserili H., et al. The R110C mutation in Notch3 causes variable clinical features in two Turkish families with CADASIL syndrome. J Neurol Sci 2006 ; 246: 123-130. (Pubitemid 43815353)
59. Utku U., Celik Y., Uyguner O., Yuksel-Apak M., Wollnik B. CADASIL syndrome in a large Turkish kindred caused by the R90C mutation in the Notch3 receptor. Eur J Neurol 2002 ; 9: 23-28.
60. Desmond DW, Moroney JT, Lynch T., et al. CADASIL in a North American family: clinical, pathologic, and radiologic findings. Neurology 1998 ; 51: 844-849. (Pubitemid 28449270)
61. Chuah TL, Tan KM, Flanagan S., et al. CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leucoencephalopathy): an Australian perspective. J Clin Neurosci 2001 ; 8: 404-406. (Pubitemid 32843690)
62. International Headache Society. International Classification of Headache Disorders. 2nd ed. Cephalalgia 2004 ; 24 (Suppl 1). 9-160.