C-Myc inhibits TP53INP1 expression via promoter methylation in esophageal carcinoma

Biochemical and Biophysical Research Communications

Volumn 405, Issue 2, 2011, Pages 278-284

  Weng, Wenhao ^a   Yang, Qinyuan ^a   Huang, Miaolong ^b   Qiao, Yongxia ^c   Xie, Yuan ^a   Yu, Yongchun ^a   jing, An ^b,d   Li, Zhi ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b YUEBEI PEOPLE S HOSPITAL   (China)

^c TONGJI UNIVERSITY   (China)

^d SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

C Myc; Esophageal carcinoma; Promoter methylation; TP53INP1

Indexed keywords

DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; MYC PROTEIN; TUMOR PROTEIN P53 INDUCED NUCLEAR PROTEIN 1; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CARRIER PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DOWN-REGULATION; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HEAT-SHOCK PROTEINS; HUMANS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-MYC;

EID: 79651469570     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.01.028     Document Type: Article

References (20)

1. Hiyam T., Yoshihara M., Tanaka S., Chayama K. Genetic polymorphisms and esophageal cancer risk. Int. J. Cancer 2007, 121:1643-1658.
2. Wobst A., Audisio R.A., Colleoni M., Geraghty J.G. Oesophageal cancer treatment: studies strategies and facts. Ann. Oncol. 1998, 9:951-962.
3. Carrier A., Nguyen C., Victorero G., Granjeaud S., Rocha D., Bernard K., Miazek A., Ferrier P., Malissen M., Naquet P., Malissen B., Jordan B.R. Differential gene expression in CD3epsilon- and RAG1-deficient thymuses: definition of a set of genes potentially involved in thymocyte maturation. Immunogenetics 1999, 50:255-270.
4. Tomasini R., Samir A.A., Vaccaro M.I., Pebusque M.J., Dagorn J.C., Iovanna J.L., Dusetti N.J. Molecular and functional characterization of the stress-induced protein (SIP) gene and its two transcripts generated by alternative splicing. SIP induced by stress and promotes cell death. J. Biol. Chem. 2001, 276:44185-44192.
5. Okamura S., Arakawa H., Tanaka T., Nakanishi H., Ng C.C., Taya Y., Monden M., Nakamura Y. p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis. Mol. Cell 2001, 8:85-94.
6. Tomasini R., Samir A.A., Carrier A., Isnardon D., Cecchinelli B., Soddu S., Malissen B., Dagorn J.C., Iovanna J.L., Dusetti N.J. TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity. J. Biol. Chem. 2003, 278:37722-37729.
7. Yoshida K., Liu H., Miki Y. Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage. J. Biol. Chem. 2006, 281:5734-5740.
8. Bonazzi V.F., Irwin D., Hayward N.K. Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma. Genes Chromosom. Cancer 2009, 48:10-21.
9. Ito Y., Motoo Y., Yoshida H., Iovanna J.L., Takamura Y., Miya A., Kuma K., Miyauchi A. Decreased expression of tumor protein p53-induced nuclear protein 1 (TP53INP1) in breast carcinoma. Anticancer Res. 2006, 26:4391-4395.
10. Jiang P.H., Motoo Y., Garcia S., Iovanna J.L., Pebusque M.J., Sawabu N. Down-expression of tumor protein p53-induced nuclear protein 1 in human gastric cancer. World J. Gastroenterol. 2006, 12:691-696.
11. Bonazzi V.F., Irwin D., Hayward N.K. Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanom. Genes Chromosom. Cancer 2009, 48:10-21.
12. Zhao X., Wang X., Zhou C., Peng R., Yan S., Wu M. Abrupt reduction of c-Myc expression by antisense RNA inducing terminal differentiation and apoptosis of a human esophageal cancer cell line. Sci. China B 1995, 38:580-589.
13. Kim S.H., Nakagawa H., Navaraj A., Naomoto Y., Klein-Szanto A.J., Rustgi A.K., El-Deiry W.S. Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras. Cancer Res. 2006, 66:10415-10424.
14. Tsuneoka M., Teye K., Arima N., Soejima M., Otera H., Ohashi K., Koga Y., Fujita H., Shirouzu K., Kimura H., Koda Y. A novel Myc-target gene, mimitin, that is involved in cell proliferation of esophageal squamous cell carcinoma. J. Biol. Chem. 2005, 280:19977-19985.
15. Bestor T., Laudano A., Mattaliano R., Ingram V. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J. Mol. Biol. 1988, 203:971-983.
16. Okano M., Xie S., Li E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 1998, 19:219-220.
17. Okano M., Bell D.W., Haber D.A., Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99:247-257.
18. Fuks F., Burgers W.A., Brehm A., Hughes-Davies L., Kouzarides T. DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat. Genet. 2000, 24:88-91.
19. Robertson K.D., Ait-Si-Ali S., Yokochi T., Wade P.A., Jones P.L., Wolffe A.P. DNMT1 forms a complex with Rb E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat. Genet. 2000, 25:338-342.
20. Brenner C., Deplus R., Didelot C., Loriot A., Vire E., De Smet C., Gutierrez A., Danovi D., Bernard D., Boon T., Pelicci P.G., Amati B., Kouzarides T., de Launoit Y., Di Croce L., Fuks F. Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J. 2005, 24:336-346.