Effects of insulin-like growth factor-I and platelet-rich plasma on sciatic nerve crush injury in a rat model: Laboratory investigation

Journal of Neurosurgery

Volumn 114, Issue 2, 2011, Pages 522-528

  Emel, Erhan ^a   Ergün, Selma Sönmez ^a   Kotan, Dilcan ^d   Gürsoy, Esra Başar ^a   Parman, Yeşim ^b   Zengin, Asli ^c   Nurten, Asiye ^c  

^a Vakif Gureba Hospital   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c ISTANBUL UNIVERSITY   (Turkey)

^d ATATURK UNIVERSITY   (Turkey)

Author keywords

Crush injury; Insulin like growth factor I; Platelet rich plasma; Rat

Indexed keywords

MYELIN; SODIUM CHLORIDE; SOMATOMEDIN C;

ANEURYSM CLIP; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; CRUSH TRAUMA; DRUG EFFECT; HISTOPATHOLOGY; INTERMETHOD COMPARISON; NERVE FIBER; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SENSORY SYSTEM; THROMBOCYTE RICH PLASMA;

ANIMALS; AXONS; INSULIN-LIKE GROWTH FACTOR I; MOTOR ACTIVITY; NERVE CRUSH; NERVE REGENERATION; PLATELET-RICH PLASMA; RANDOM ALLOCATION; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; SCIATIC NERVE; SCIATIC NEUROPATHY; STATISTICS, NONPARAMETRIC; TREATMENT OUTCOME;

EID: 79551718505     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2010.9.JNS091928     Document Type: Article

References (49)

1. Allamargot C, Pouplard-Barthelaix A, Fressinaud C: A single intracerebral microinjection of platelet-derived growth factor (PDGF) accelerates the rate of remyelination in vivo. Brain Res 918:28-39, 2001 (Pubitemid 33001486)
2. Aspenberg P, Virchenko O: Platelet concentrate injection improves Achilles tendon repair in rats. Acta Orthop Scand 75: 93-99, 2004 (Pubitemid 38264933)
3. Bain JR, Mackinnon SE, Hunter DA: Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat. Plast Reconstr Surg 83:129-138, 1989
4. Bendszus M, Wessig C, Schütz A, Horn T, Kleinschnitz C, Sommer C, et al: Assessment of nerve degeneration by gadofluorine M-enhanced magnetic resonance imaging. Ann Neurol 57:388-395, 2005 (Pubitemid 40343961)
5. Cheng HL, Russell JW, Feldman EL: IGF-I promotes peripheral nervous system myelination. Ann N Y Acad Sci 883: 124-130, 1999 (Pubitemid 129495422)
6. Colohan AR, Pitts LH, Rosegay H: Injury to the peripheral nerves, in Feliciano DV, Moore EE, Mattox KL (eds): Trauma, ed 3. Stamford, CT: Appleton & Lange, 1996, pp 853-862
7. Cudlip SA, Howe FA, Griffiths JR, Bell BA: Magnetic resonance neurography of peripheral nerve following experimental crush injury, and correlation with functional deficit. J Neurosurg 96:755-759, 2002 (Pubitemid 34245633)
8. Danielsen N, Pettmann B, Vahlsing HL, Manthorpe M, Varon S: Fibroblast growth factor effects on peripheral nerve regeneration in a silicone chamber model. J Neurosci Res 20:320-330, 1988
9. Davis JB, Stroobant P: Platelet-derived growth factors and fibroblast growth factors are mitogens for rat Schwann cells. J Cell Biol 110:1353-1360, 1990
10. Day CS, Buranapanitkit B, Riano FA, Tomaino MM, Somogyi G, Sotereanos DG, et al: Insulin growth factor-1 decreases muscle atrophy following denervation. Microsurgery 22: 144-151, 2002 (Pubitemid 34721642)
11. Denny-Brown D, Brenner C: Paralysis of nerve induced by direct pressure and by tourniquet. Arch Neurol Psychiatry 51:1-26, 1944
12. Eccleston PA, Funa K, Heldin CH: Expression of platelet-derived growth factor (PDGF) and PDGF alpha- and beta-receptors in the peripheral nervous system: an analysis of sciatic nerve and dorsal root ganglia. Dev Biol 155:459-470, 1993 (Pubitemid 23076005)
13. Fex Svenningsen A, Kanje M: Insulin and the insulin-like growth factors I and II are mitogenic to cultured rat sciatic nerve segments and stimulate [3H]thymidine incorporation through their respective receptors. Glia 18:68-72, 1996
14. Froesch ER, Schmid C, Schwander J, Zapf J: Actions of insulin-like growth factors. Annu Rev Physiol 47:443-467, 1985 (Pubitemid 15142391)
15. Frostick SP, Yin Q, Kemp GJ: Schwann cells, neurotrophic factors, and peripheral nerve regeneration. Microsurgery 18: 397-405, 1998 (Pubitemid 29014397)
16. Garg AK, Gargenese D, Peace I: Using platelet-rich plasma to develop an autologous membrane for growth factor delivery in dental implant therapy. Dent Implantol Update 11:41-44, 2000
17. Glazner GW, Morrison AE, Ishii DN: Elevated insulin-like growth factor (IGF) gene expression in sciatic nerves during IGF-supported nerve regeneration. Brain Res Mol Brain Res 25:265-272, 1994 (Pubitemid 24266077)
18. Grant GA, Goodkin R, Kliot M: Evaluation and surgical management of peripheral nerve problems. Neurosurgery 44: 825-840, 1999 (Pubitemid 29153576)
19. Hansson HA: Insulin-like growth factors and nerve regeneration. Ann N Y Acad Sci 692:161-171, 1993
20. Harrison P, Cramer EM: Platelet alpha-granules. Blood Rev 7:52-62, 1993
21. Jarvik JG, Yuen E, Kliot M: Diagnosis of carpal tunnel syndrome: electrodiagnostic and MR imaging evaluation. Neuroimaging Clin N Am 14:93-102, viii, 2004
22. Kanje M, Skottner A, Sjöberg J, Lundborg G: Insulin-like growth factor I (IGF-I) stimulates regeneration of the rat sciatic nerve. Brain Res 486:396-398, 1989 (Pubitemid 19135156)
23. Lutz BS, Wei FC, Ma SF, Chuang DC: Effects of insulin-like growth factor-1 in motor nerve regeneration after nerve transection and repair vs. nerve crushing injury in the rat. Acta Neurochir (Wien) 141:1101-1106, 1999 (Pubitemid 29494908)
24. Marx RE: Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant Dent 10:225-228, 2001
25. Marx RE: Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg 62:489-496, 2004
26. Millesi H: Brachial plexus injuries. Management and results. Clin Plast Surg 11:115-120, 1984
27. Mulholland MW, Romanchuk G, Simeone DM, Flowe K: Stimulation of myenteric plexus neurite outgrowth by insulin and insulin-like growth factors I and II. Life Sci 51:1789-1796, 1992
28. Ochoa J, Fowler TJ, Gilliatt RW: Anatomical changes in peripheral nerves compressed by a pneumatic tourniquet. J Anat 113:433-455, 1972
29. Oya T, Zhao YL, Takagawa K, Kawaguchi M, Shirakawa K, Yamauchi T, et al: Platelet-derived growth factor-b expression induced after rat peripheral nerve injuries. Glia 38:303-312, 2002
30. Powell HC, Myers RR: Pathology of experimental nerve compression. Lab Invest 55:91-100, 1986 (Pubitemid 16011582)
31. Recio-Pinto E, Ishii DN: Effects of insulin, insulin-like growth factor-II and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells. Brain Res 302:323-334, 1984 (Pubitemid 14077761)
32. Richardson PM, Thomas PK: Percussive injury to peripheral nerve in rats. J Neurosurg 51:178-187, 1979 (Pubitemid 9238762)
33. Ridley AJ, Davis JB, Stroobant P, Land H: Transforming growth factors-beta 1 and beta 2 are mitogens for rat Schwann cells. J Cell Biol 109:3419-3424, 1989 (Pubitemid 20017991)
34. Rinderknecht E, Humbel RE: The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. J Biol Chem 253:2769-2776, 1978 (Pubitemid 8326483)
35. Rydevik B, Lundborg G: Permeability of intraneural microvessels and perineurium following acute, graded experimental nerve compression. Scand J Plast Reconstr Surg 11:179-187, 1977 (Pubitemid 8285746)
36. Samir M Watson JT: Platelet rich concentrate: basic science and current clinical applications. J Orthop Trauma 22:432-438, 2008
37. Sandberg Nordqvist AC, von Holst H, Holmin S, Sara VR, Bellander BM, Schalling M: Increase of insulin-like growth factor (IGF)-1, IGF binding protein-2 and -4 mRNAs following cerebral contusion. Brain Res Mol Brain Res 38:285-293, 1996 (Pubitemid 26168288)
38. Sarikcioglu L, Ozkan O: Yasargil-Phynox aneurysm clip: a simple and reliable device for making a peripheral nerve injury. Int J Neurosci 113:455-464, 2003 (Pubitemid 36538526)
39. Sharon I, Fishfeld CI: Acute nerve injury. (http://emedicine.medscape. com/article/249621-overview) [Accessed September 21, 2010]
40. Sjöberg J, Kanje M: Insulin-like growth factor (IGF-1) as a stimulator of regeneration in the freeze-injured rat sciatic nerve. Brain Res 485:102-108, 1989 (Pubitemid 19096286)
41. Sondell M, Lundborg G, Kanje M: Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J Neurosci 19:5731-5740, 1999 (Pubitemid 29327910)
42. Thanos PK, Okajima S, Tiangco DA, Terzis JK: Insulin-like growth factor-I promotes nerve regeneration through a nerve graft in an experimental model of facial paralysis. Restor Neurol Neurosci 15:57-71, 1999 (Pubitemid 29484556)
43. Thomas PK, Landon DN, King RHM: Diseases of the peripheral nerves, in Adams JH, Duchen LW (eds): Greenfield's Neuropathology, ed. 5. Oxford: Oxford University Press, 1992, pp 1116-1245
44. Tiangco DA, Papakonstantinou KC, Mullinax KA, Terzis JK: IGF-I and end-to-side nerve repair: a dose-response study. J Reconstr Microsurg 17:247-256, 2001 (Pubitemid 32480073)
45. Vergani L, Di Giulio AM, Losa M, Rossoni G, Muller EE, Gorio A: Systemic administration of insulin-like growth factor decreases motor neuron cell death and promotes muscle reinnervation. J Neurosci Res 54:840-847, 1998 (Pubitemid 28544385)
46. Wang C, Li Y, Wible B, Angelides KJ, Ishii DN: Effects of insulin and insulin-like growth factors on neurofilament mRNA and tubulin mRNA content in human neuroblastoma SHSY5Y cells. Brain Res Mol Brain Res 13:289-300, 1992
47. Welch JA, Kraus KH, Wells MR, Blunt DG, Weremowitz J: Effect of combined administration of insulin-like growth factor and platelet-derived growth factor on the regeneration of transected and anastomosed sciatic nerve in rats. Am J Vet Res 58:1033-1037, 1997 (Pubitemid 127470269)
48. Zapf J, Waldvogel M, Froesch ER: Binding of nonsuppressible insulinlike activity to human serum. Evidence for a carrier protein. Arch Biochem Biophys 168:638-645, 1975
49. Zimmermann R, Arnold D, Strasser E, Ringwald J, Schlegel A, Wiltfang J, et al: Sample preparation technique and white cell content influence the detectable levels of growth factors in platelet concentrates. Vox Sang 85:283-289, 2003 (Pubitemid 37522602)