Changes to tear cytokines of type 2 diabetic patients with or without retinopathy

Molecular Vision

Volumn 16, Issue , 2010, Pages 2931-2938

  Liu, Jingfang ^a   Shi, Bingyin ^a   He, Shuixiang ^a   Yao, Xiaoli ^a   Willcox, Mark D P ^b,c   Zhao, Zhenjun ^b,c  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b BRIEN HOLDEN VISION INSTITUTE   (Australia)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; EOTAXIN; FIBROBLAST GROWTH FACTOR; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOGLOBIN A1C; IMMUNOGLOBULIN A; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; INTERLEUKIN 9; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR BB; RANTES;

ADULT; ARTICLE; CLINICAL ARTICLE; CORRELATION ANALYSIS; DIABETIC RETINOPATHY; DISEASE DURATION; FEMALE; HEMOGLOBIN BLOOD LEVEL; HUMAN; IMMUNOASSAY; IMMUNOGLOBULIN BLOOD LEVEL; LACRIMAL FLUID; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; TH1 CELL; TH2 CELL;

ANGIOGENESIS INDUCING AGENTS; ANGIOGENESIS INHIBITORS; CASE-CONTROL STUDIES; CYTOKINES; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; HUMANS; IMMUNOGLOBULIN A; MALE; MIDDLE AGED; PHENOTYPE; TEARS; TH1 CELLS; TH2 CELLS;

EID: 79551712372     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Schultz RO, Van Horn DL, Peters MA, Klewin KM, Schutten WH. Diabetic keratopathy. Trans Am Ophthalmol Soc 1981; 79:180-199. [PMID: 7342400]
2. Schultz RO, Matsuda M, Yee RW, Edelhauser HF, Schultz KJ. Corneal endothelial changes in type I and type II diabetes mellitus. Am J Ophthalmol 1984; 98:401-410. [PMID: 6486211]
3. Friend J, Thoft RA. The diabetic cornea. Int Ophthalmol Clin 1984; 24:111-123. [PMID: 6500867]
4. Herse PR. A review of manifestations of diabetes mellitus in the anterior eye and cornea. Am J Optom Physiol Opt 1988; 65:224-230. [PMID: 3284372]
5. Fong DS, Aiello L, Gardner TW, King GL, Blankenship G, Cavallerano JD, Ferris FL 3rd, Klein R. Retinopathy in diabetes. Diabetes Care 2004; 27:S84-S87. [PMID: 14693935]
6. Funatsu H, Yamashita H, Noma H, Mimura T, Nakamura S, Sakata K, Hori S. Aqueous humor levels of cytokines are related to vitreous levels and progression of diabetic retinopathy in diabetic patients. Graefes Arch Clin Exp Ophthalmol 2005; 243:3-8. [PMID: 15258777]
7. Demircan N, Safran BG, Soylu M, Ozcan AA, Sizmaz S. Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy. Eye (Lond) 2006; 20:1366-1369. [PMID: 16284605]
8. Yuuki T, Kanda T, Kimura Y, Kotajima N, Tamura J, Kobayashi I, Kishi S. Inflammatory cytokines in vitreous fluid and serum of patients with diabetic vitreoretinopathy. J Diabetes Complications 2001; 15:257-259. [PMID: 11522500]
9. Abu El-Asrar AM, Struyf S, Kangave D, Geboes K, Van Damme J. Chemokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy. Eur Cytokine Netw 2006; 17:155-165. [PMID: 17194635]
10. Hernández C, Segura RM, Fonollosa A, Carrasco E, Francisco G, Simo R. Interleukin-8, monocyte chemoattractant protein-1 and IL-10 in the vitreous fluid of patients with proliferative diabetic retinopathy. Diabet Med 2005; 22:719-722. [PMID: 15910622]
11. Mitamura Y, Takeuchi S, Matsuda A, Tagawa Y, Mizue Y, Nishihira J. Monocyte chemotactic protein-1 in the vitreous of patients with proliferative diabetic retinopathy. Ophthalmologica 2001; 215:415-418. [PMID: 11741107]
12. Adamis AP, Berman AJ. Immunological mechanisms in the pathogenesis of diabetic retinopathy. Semin Immunopathol 2008; 30:65-84. [PMID: 18340447]
13. Saini JS, Khandalavla B. Corneal epithelial fragility in diabetes mellitus. Can J Ophthalmol 1995; 30:142-146. [PMID: 7627899]
14. Rogell GD. Corneal hypesthesia and retinopathy in diabetes mellitus. Ophthalmology 1980; 87:229-33. [PMID: 7191550]
15. Chatterjee PR, De S, Datta H, Chatterjee S, Biswas MC, Sarkar K, Mandal LK. Estimation of tear glucose level and its role as a prompt indicator of blood sugar level. J Indian Med Assoc 2003; 101:481-483. [PMID: 15071801]
16. Ramos-Remus C, Suarez-Almazor M, Russell AS. Low tear production in patients with diabetes mellitus is not due to Sjogren's syndrome. Clin Exp Rheumatol 1994; 12:375-380. [PMID: 7955600]
17. Nepp J, Abela C, Polzer I, Derbolav A, Wedrich A. Is there a correlation between the severity of diabetic retinopathy and keratoconjunctivitis sicca? Cornea 2000; 19:487-491. [PMID: 10928764]
18. Pflugfelder SC, Jones D, Ji Z, Afonso A, Monroy D. Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjogren's syndrome keratoconjunctivitis sicca. Curr Eye Res 1999; 19:201-211. [PMID: 10487957]
19. Inoue K, Kato S, Ohara C, Numaga J, Amano S, Oshika T. Ocular and systemic factors relevant to diabetic keratoepitheliopathy. Cornea 2001; 20:798-801. [PMID: 11685054]
20. Zhao Z, Aliwarga Y, Willcox MD. Intrinsic protein fluorescence interferes with detection of tear glycoproteins in SDS-polyacrylamide gels using extrinsic fluorescent dyes. J Biomol Tech 2007; 18:331-335. [PMID: 18166676]
21. Massingale ML, Li X, Vallabhajosyula M, Chen D, Wei Y, Asbell PA. Analysis of inflammatory cytokines in the tears of dry eye patients. Cornea 2009; 28:1023-1027. [PMID: 19724208]
22. Malvitte L, Montange T, Vejux A, Baudouin C, Bron AM, Creuzot-Garcher C, Lizard G. Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs. Br J Ophthalmol 2007; 91:29-32. [PMID: 16943231]
23. Fukagawa K, Nakajima T, Tsubota K, Shimmura S, Saito H, Hirai K. Presence of eotaxin in tears of patients with atopic keratoconjunctivitis with severe corneal damage. J Allergy Clin Immunol 1999; 103:1220-1221. [PMID: 10359913]
24. Moschos MM, Eperon S, Guex-Crosier Y. Increased eotaxin in tears of patients wearing contact lenses. Cornea 2004; 23:771-775. [PMID: 15502476]
25. Cook EB, Stahl JL, Lowe L, Chen R, Morgan E, Wilson J, Varro R, Chan A, Graziano FM, Barney NP. Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs. non-allergics. J Immunol Methods 2001; 254:109-118. [PMID: 11406157]
26. Leonardi A, Curnow SJ, Zhan H, Calder VL. Multiple cytokines in human tear specimens in seasonal and chronic allergic eye disease and in conjunctival fibroblast cultures. Clin Exp Allergy 2006; 36:777-784. [PMID: 16776679]
27. LaFrance MW, Kehinde LE, Fullard RJ. Multiple cytokine analysis in human tears: an optimized procedure for cytometric bead-based assay. Curr Eye Res 2008; 33:525-544. [PMID: 18600485]
28. Fullard RJ, Snyder C. Protein levels in nonstimulated and stimulated tears of normal human subjects. Invest Ophthalmol Vis Sci 1990; 31:1119-1126. [PMID: 2354914]
29. Maier R, Weger M, Haller-Schober EM, El-Shabrawi Y, Wedrich A, Theisl A, Aigner R, Barth A, Haas A. Multiplex bead analysis of vitreous and serum concentrations of inflammatory and proangiogenic factors in diabetic patients. Mol Vis 2008; 14:637-643. [PMID: 18385799]
30. Arend WP. Interleukin-1 receptor antagonist. Adv Immunol 1993; 54:167-227. [PMID: 8379462]
31. Eizirik DL, Tracey DE, Bendtzen K, Sandler S. An interleukin-1 receptor antagonist protein protects insulinproducing beta cells against suppressive effects of interleukin-1 beta. Diabetologia 1991; 34:445-448. [PMID: 1832112]
32. Mandrup-Poulsen T, Zumsteg U, Reimers J, Pociot F, Morch L, Helqvist S, Dinarello CA, Nerup J. Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic betacell destruction in insulin-dependent diabetes mellitus. Cytokine 1993; 5:185-191. [PMID: 8218929]
33. Nyengaard JR, Ido Y, Kilo C, Williamson JR. Interactions between hyperglycemia and hypoxia: implications for diabetic retinopathy. Diabetes 2004; 53:2931-2938. [PMID: 15504974]
34. Dogru M, Katakami C, Inoue M. Tear function and ocular surface changes in noninsulin-dependent diabetes mellitus. Ophthalmology 2001; 108:586-592. [PMID: 11237914]
35. Salcedo R, Ponce ML, Young HA, Wasserman K, Ward JM, Kleinman HK, Oppenheim JJ, Murphy WJ. Humanendothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood 2000; 96:34-40. [PMID: 10891427]
36. Hong KH, Ryu J, Han KH. Monocyte chemoattractant protein-1-induced angiogenesis is mediated by vascular endothelial growth factor-A. Blood 2005; 105:1405-1407. [PMID: 15498848]
37. Matsuda A, Fukuda S, Matsumoto K, Saito H. Th1/Th2 cytokines reciprocally regulate in vitro pulmonary angiogenesis via CXC chemokine synthesis. Am J Respir Cell Mol Biol 2008; 38:168-175. [PMID: 17709600]
38. Sgadari C, Angiolillo AL, Tosato G. Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10. Blood 1996; 87:3877-3882. [PMID: 8611715]
39. Pakneshan P, Birsner AE, Adini I, Becker CM, D'Amato RJ. Differential suppression of vascular permeability and corneal angiogenesis by nonsteroidal anti-inflammatory drugs. Invest Ophthalmol Vis Sci 2008; 49:3909-3913. [PMID: 18487370]
40. Zorena K, Mysliwska J, Mysliwiec M, Balcerska A, Lipowski P, Raczynska K. Interleukin-12 and tumour necrosis factoralpha equilibrium is a prerequisite for clinical course free from late complications in children with type 1 diabetes mellitus. Scand J Immunol 2008; 67:204-208. [PMID: 18201373]
41. Alberti S, Cevenini E, Ostan R, Capri M, Salvioli S, Bucci L, Ginaldi L, De Martinis M, Franceschi C, Monti D. Agedependent modifications of Type 1 and Type 2 cytokines within virgin and memory CD4+ T cells in humans. Mech Ageing Dev 2006; 127:560-566. [PMID: 16516272]
42. Bruunsgaard H, Andersen-Ranberg K, Jeune B, Pedersen AN, Skinhoj P, Pedersen BK. A high plasma concentration of TNF-alpha is associated with dementia in centenarians. J Gerontol A Biol Sci Med Sci 1999; 54:M357-M364. [PMID: 10462168]
43. Liu TF, Jones BM. Impaired production of IL-12 in systemic lupus erythematosus. I. Excessive production of IL-10 suppresses production of IL-12 by monocytes. Cytokine 1998; 10:140-147. [PMID: 9512904]
44. Segal R, Dayan M, Globerson A, Habut B, Shearer GM, Mozes E. Effect of aging on cytokine production in normal and experimental systemic lupus erythematosus afflicted mice. Mech Ageing Dev 1997; 96:47-58. [PMID: 9223110]
45. Netea MG, Hancu N, Blok WL, Grigorescu-Sido P, Popa L, Popa V, van der Meer JW. Interleukin 1 beta, tumour necrosis factor-alpha and interleukin 1 receptor antagonist in newly diagnosed insulin-dependent diabetes mellitus: comparison to long-standing diabetes and healthy individuals. Cytokine 1997; 9:284-287. [PMID: 9112337]
46. Kuzuya T. Early diagnosis, early treatment and the new diagnostic criteria of diabetes mellitus. Br J Nutr 2000; 84:S177-S181. [PMID: 11242465]
47. Yoon KC, Im SK, Seo MS. Changes of tear film and ocular surface in diabetes mellitus. Korean J Ophthalmol 2004; 18:168-174. [PMID: 15635831]
48. Kaiserman I, Kaiserman N, Nakar S, Vinker S. Dry eye in diabetic patients. Am J Ophthalmol 2005; 139:498-503. [PMID: 15767060]
49. Hernández C, Segura RM, Fonollosa A, Carrasco E, Francisco G, Simó R. Interleukin-8, monocyte chemoattractant protein-1 and IL-10 in the vitreous fluid of patients with proliferative diabetic retinopathy. Diabet Med 2005; 22:719-722. [PMID: 15910622]