Background migration of USPIO/MLs is a major drawback for in situ labeling of endogenous neural progenitor cells

Contrast Media and Molecular Imaging

Volumn 6, Issue 1, 2011, Pages 1-6

  Vreys, Ruth ^a   Soenen, Stefaan J H ^b   De Cuyper, Marcel ^b   Van Der Linden, Annemie ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Contrast agents; in situ cell labeling; Magnetic resonance imaging; Magnetoliposomes; USPIOs; White matter

Indexed keywords

ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LABELING; CELL MIGRATION; CONTROLLED STUDY; INJECTION; MALE; MOUSE; NEURAL STEM CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OLFACTORY BULB; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; SURFACE PROPERTY; WHITE MATTER;

ADULT STEM CELLS; ANIMALS; CELL MOVEMENT; CELL TRACKING; CONTRAST MEDIA; FALSE POSITIVE REACTIONS; FERUMOXYTOL; IN SITU HYBRIDIZATION; LIPOSOMES; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED C57BL; MOVEMENT; NEURAL STEM CELLS; PARTICLE SIZE; STAINING AND LABELING;

EID: 79551698116     PISSN: 15554309     EISSN: 15554317     Source Type: Journal    
DOI: 10.1002/cmmi.390     Document Type: Article

References (27)

1. Shapiro EM, Gonzalez-Perez O, Garcia-Verdugo JM, Alvarez-Buylla A, Koretsky AP. Magnetic resonance imaging of the migration of neuronal precursors generated in the adult rodent brain. NeuroImage 2006; 32: 1150-1157; doi: 10.1016/j.neuroimage.2006.04.219
2. Sumner JP, Shapiro EM, Maric D, Conroy R, Koretsky AP. In vivo labeling of adult neural progenitors for MRI with micron sized particles of iron oxide: quantification of labeled cell phenotype. NeuroImage 2009; 44: 671-678; doi: 10.1016/j.neuroimage.2008.07.050
3. Vreys R, Vande Velde G, Krylychkina O, et al. MRI visualization of endogenous neural progenitor cell migration along the RMS in the adult mouse brain: validation of various MPIO labeling strategies. NeuroImage 2010; 49: 2094-2103; doi: 10.1016/j.neuroimage.2009.10.034
4. Modo M, Hoehn M, Bulte JW. Cellular MR imaging. Mol Imaging 2005; 4: 143-164.
5. Soenen SJ, Hodenius M, De Cuyper M. Magnetoliposomes: versatile innovative nanocolloids for use in biotechnology and biomedicine. Nanomedicine 2009; 4: 177-191; doi: 10.2217/17435889.4.2.177
6. Bulte JW, De Cuyper M, Despres D, Frank JA. Short- vs. long-circulating magnetoliposomes as bone marrow-seeking MR contrast agents. J Magn Reson Imaging 1999; 9: 329-335.
7. Soenen SJ, Baert J, De Cuyper M. Optimal conditions for labelling of 3T3 fibroblasts with magnetoliposomes without affecting cellular viability. Chembiochem 2007; 8: 2067-2077; doi: 10.1002/cbic.200700327
8. Brunjes PC, Illig KR, Meyer EA. A field guide to the anterior olfactory nucleus (cortex). Brain Res Rev 2005; 50: 305-335; doi: 10.1016/j.brainresrev.2005.08.005
9. Alvarez-Buylla A, Garcia-Verdugo JM, Tramontin AD. A unified hypothesis on the lineage of neural stem cells. Nat Rev Neurosci 2001; 2: 287-293; doi: 10.1038/35067582
10. Lois C, Alvarez-Buylla A. Long-distance neuronal migration in the adult mammalian brain. Science 1994; 264: 1145-1148; doi: 10.1126/science.8178174
11. Luskin MB. Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron 1993; 11: 173-189; doi: 10.1016/0896-6273(93)90281-U
12. Kato T, Yokouchi K, Fukushima N, Kawagishi K, Li Z, Moriizumi T. Continual replacement of newly-generated olfactory neurons in adult rats. Neurosci Lett 2001; 307: 17-20; doi: 10.1016/S0304-3940(01)01914-0
13. Desestret V, Brisset JC, Moucharrafie S, et al. Early-stage investigations of ultrasmall superparamagnetic iron oxide-induced signal change after permanent middle cerebral artery occlusion in mice. Stroke 2009; 40: 1834-1841; doi: 10.1161/STROKEAHA.108.531269
14. Rausch M, Baumann D, Neubacher U, Rudin M. In-vivo visualization of phagocytotic cells in rat brains after transient ischemia by USPIO. NMR Biomed 2002; 15: 278-283; doi: 10.1002/nbm.770
15. Justicia C, Himmelreich U, Ramos-Cabrer P, Sprenger C, Hoehn M. In vivo tracking of endogenous stem cells by MRI after intraparenchymal injection of iron oxide nanoparticles. Mol Imag 2005; 4: 351-352.
16. Abbott NJ. Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology. Neurochem Int 2004; 45: 545-552; doi: 10.1016/j.neuint.2003.11.006
17. Thorne RG, Nicholson C. In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space. Proc Natl Acad Sci USA 2006; 103: 5567-5572; doi: 10.1073/pnas.0509425103
18. Hoehn M, Wiedermann D, Justicia C, et al. Cell tracking using magnetic resonance imaging. J Physiol 2007; 584: 25-30; doi: 10.1113/jphysiol.2007.139451
19. Boutry S, Brunin S, Mahieu I, Laurent S, Vander Elst L, Muller RN. Magnetic labeling of non-phagocytic adherent cells with iron oxide nanoparticles: a comprehensive study. Contrast Media Mol Imag 2008; 3: 223-232; doi: 10.1002/cmmi.256
20. Soenen SJ, Illyes E, Vercauteren D, et al. The role of nanoparticle concentration-dependent induction of cellular stress in the internalization of non-toxic cationic magnetoliposomes. Biomaterials 2009; 30: 6803-6813; doi: 10.1016/j.biomaterials.2009.08.050
21. Saito R, Krauze MT, Noble CO, et al. Tissue affinity of the infusate affects the distribution volume during convection-enhanced delivery into rodent brains: implications for local drug delivery. J Neurosci Meth 2006; 154: 225-232; doi: 10.1016/j.jneumeth.2005.12.027
22. Lynch I, Salvati A, Dawson KA. Protein-nanoparticle interactions: what does the cell see? Nat Nanotechnol 2009; 4: 546-547; doi: 10.1038/nnano.2009.248
23. Mailänder V, Lorenz MR, Holzapfel V, et al. Carboxylated superparamagnetic iron oxide particles label cells intracellularly without transfection agents. Mol Imag Biol 2008; 10: 138-146; doi: 10.1007/s11307-007-0130-3
24. Schäfer R, Kehlbach R, Wiskirchen J, et al. Transferrin receptor upregulation: in vitro labeling of rat mesenchymal stem cells with superparamagnetic iron oxide. Radiology 2007; 244: 514-523; doi: 10.1148/radiol.2442060599
25. De Cuyper M, Joniau M. Mechanistic aspects of the adsorption of phospholipids onto lauric acid stabilized magnetite nanocolloids. Langmuir 1991; 7: 647-652; doi: 10.1021/la00052a010
26. De Cuyper M, Baert J, Cocquyt J, Van der Meeren P. A successful strategy for the production of cationic magnetoliposomes. Z Phys Chem 2006; 220: 133-141.
27. Soenen SJ, Brisson AR, De Cuyper M. Addressing the problem of cationic lipid-mediated toxicity: the magnetoliposome model. Biomaterials 2009; 30: 3691-3701; doi: 10.1016/j.biomaterials.2009.03.040