Effects of mechanical tensile stress on the expression of ODF mRNA in osteoblasts differentiated from rBMSCs in vitro

Yiyong Shengwu Lixue/Journal of Medical Biomechanics

Volumn 25, Issue 6, 2010, Pages

  Jiang, Ling Yong ^a,b   Zhao, Zhi He ^b   Wang, Jun ^b   Fan, Yu Bo ^c  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SICHUAN UNIVERSITY   (China)

^c BEIHANG UNIVERSITY   (China)

Author keywords

Gene expression; Mesenchymal stem cells; Osteoblasts; Osteoclast differentiation factor(ODF); Tensile stress

Indexed keywords

BONE MODELING AND REMODELING; BONE RESORPTION; CONTROL GROUPS; EXPRESSION PATTERNS; IN-VITRO; MECHANICAL STRAIN; MESENCHYMAL STEM CELLS; MOLECULAR BASIS; MRNA LEVEL; OSTEOCLAST DIFFERENTIATION; OSTEOCLASTOGENESIS; SEMI-QUANTITATIVE RT-PCR; STRESS LOADING; STRESS SYSTEM; TOOTH MOVEMENT;

BONE; CELL CULTURE; DYNAMICS; GENES; NUCLEIC ACIDS; OSTEOBLASTS; POLYMERASE CHAIN REACTION; STEM CELLS; STRESS ANALYSIS; TENSILE STRESS; TRANSCRIPTION;

TENSILE STRAIN;

EID: 79551694644     PISSN: 10047220     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Lundberg P, Lie A, Bjurholm A, et al. Vasoactive intestinal peptide regulates osteoclast activity via specific binding sites on both osteoclasts and osteoblasts[J]. Bone, 2000, 27(6): 803-810.
2. Hofbauer LC, Khosla S, Dunstan CR, et al. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption[J]. J Bone Miner Res, 2000, 15(1): 2-12.
3. Maniatopoulos C, Sodek J, Melcher AH. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats[J]. Cell Tissue Res, 1988, 254(2): 317-330.
4. Yashuda H, Shima N, Nakagawa N, et al. A Novel Molecular Mechanism Modulating Osteoclast Differentiation and Function[J]. Bone, 1999, 25(1): 109-113.
5. Shiotani A, Takami M, Itoh K, et al. Regulation of osteoclast differentiation and function by receptor activator of NFkB ligand and osteoprotegerin[J]. Anat Rec 2002, 268(2): 137-146.
6. Simonet WS, Lacey DL, Dunstan CR, et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density[J]. Cell, 1997, 89(2): 309-519.
7. Wong BR, Rho J, Arron J, et al. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells[J]. J Biol Chem, 1997, 272(40): 25190-25194.
8. Friedenstein AJ, Latzinik NV, Gorskaya YF, et al. Bone marrow stromal colony formation requires stimulation by haemopoietic cells[J]. Bone Miner, 1992, 18(3): 199-213.
9. 2006, 37(3): 438-441.
10. Brown TD. Techniques for mechanical stimulation of cells in vitro-a review[J]. Journal of Biomechanics, 2000, 33: 3-14.
11. Yamaguchi M, Shimizu N, Shibata Y, et al. Effects of different magnitudes of tension-force on alkaline phosphatase activity in periodontal ligament cells[J]. J Dent Res, 1996, 75(3): 889-894.
12. 1999.
13. Rubin J, Murphy TC, Fan X, et al. Mechanical strain inhibits RANKL expression through activation of ERK1/2 in bone marrow stromal cells[J]. Journal Bone and Mineral Research, 2002, 17: 1452-1460.
14. Rodan GA, Martin TJ. Role of osteoclasts in hormonal control of bone resorption-a hypothesis[J]. Calcif Tissue Int, 1981, 33: 349-351.
15. Takahashi N, Akatsu T, Uadagawa N, et al. Osteoblastic cells are involved in osteoclast formation[J]. Endocrinology, 1988, 123: 2600-2602.
16. Tanaka Y, Maruo A, Fujiik, et al. Intercellular adhesion molecule I discriminates functionally different populations of human osteoblasts: characteristics involvement of cell cycle regulations[J]. J Bone Miner Res, 2000, 15(10): 1912-1923.
17. Simonet WS, Lacey DL, Dunstan CR, et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density[J]. Cell, 1997, 89(2): 309-319.
18. Lacey DL, Timms E, Tan HL, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation[J]. Cell, 1998, 93(2): 165-176.
19. Tanaka S, Takahashi N, Udagawa N, et al. Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors[J]. J Clin Invest, 1993, 91: 257-263.
20. Anderson DM, Maraskovsky E, Billingsley WL, et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function[J]. Nature, 1997, 390(6656): 175-179.
21. Yashuda H, Shima N, Nakagawa N, et al. A novel molecular mechanism modulating osteoclast differentiation and function[J]. Bone, 1999, 25(1): 109-113.
22. Rubin J, Fan X, Biskobing DM, et al. Osteoclastogenesis is repressed by mechanical strain in an in vitro model[J]. J Orthop Res, 1999, 17(5): 639-645.