[11C]GR103545: Novel one-pot radiosynthesis with high specific activity

Nuclear Medicine and Biology

Volumn 38, Issue 2, 2011, Pages 215-221

  Nabulsi, Nabeel B ^a   Zheng, Ming Qiang ^a   Ropchan, Jim ^a   Labaree, David ^a   Ding, Yu Shin ^a   Blumberg, Laura ^b   Huang, Yiyun ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

11C GR103545; Carbamate; DBU; Kappa Opioid; PET; Radiosynthesis

Indexed keywords

4 [(3,4 DICHLOROPHENYL)ACETYL] 3 (1 PYRROLIDINYLMETHYL) 1 PIPERAZINECARBOXYLIC ACID METHYL ESTER; CARBAMIC ACID; CARBON 11; TRACER; 1,8 DIAZABICYCLO(5.4.0)UNDEC 7 ENE; 1,8-DIAZABICYCLO(5.4.0)UNDEC-7-ENE; CARBAMIC ACID DERIVATIVE; CARBON; CARBON DIOXIDE; DIAGNOSTIC AGENT; FUSED HETEROCYCLIC RINGS; KAPPA OPIATE RECEPTOR; PIPERAZINE DERIVATIVE; PYRROLIDINE DERIVATIVE;

ARTICLE; AUTOANALYSIS; CARBOXYLATION; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG PURITY; DRUG STRUCTURE; ISOTOPE LABELING; ISOTOPE TRACING; METHYLATION; ONE POT SYNTHESIS; PROCESS DEVELOPMENT; RADIOACTIVITY; RADIOCHEMISTRY; RADIOISOTOPE DIAGNOSIS; REPRODUCIBILITY; CHEMISTRY; DRUG POTENTIATION; METHODOLOGY; SYNTHESIS;

BICYCLO COMPOUNDS, HETEROCYCLIC; CARBAMATES; CARBON DIOXIDE; CARBON RADIOISOTOPES; PIPERAZINES; PYRROLIDINES; RADIOCHEMISTRY; RECEPTORS, OPIOID, KAPPA;

EID: 79551683526     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2010.08.014     Document Type: Article

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