Portable imaging system for on-site analysis using CMOS imager-microfluidic analysis and fluorescence imaging

IEEJ Transactions on Electrical and Electronic Engineering

Volumn 6, Issue 2, 2011, Pages 97-100

  Misawa, Nobuo ^a   Takeuchi, Shoji ^b,c  

^a TOYOHASHI UNIVERSITY OF TECHNOLOGY   (Japan)

^b INSTITUTE OF INDUSTRIAL SCIENCE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Complementary metal oxide semiconductor imager; Organic light emitting diode; Poly(dimethylsiloxane) microfluidic channel

Indexed keywords

FLUIDIC DEVICES; FLUORESCENCE; IMAGING SYSTEMS; LAPTOP COMPUTERS; LIGHT EMISSION; LIGHT EMITTING DIODES; LIGHT SOURCES; METAL ANALYSIS; METALLIC COMPOUNDS; MICROFLUIDICS; MOS DEVICES; SEMICONDUCTOR DIODES; TRANSISTORS;

CMOS IMAGERS; CMOS IMAGING; COMPLEMENTARY METAL OXIDE SEMICONDUCTORS; FLUORESCENCE DETECTION; FLUORESCENCE IMAGING; MICROFLUIDIC ANALYSIS; MICROFLUIDIC ASSAYS; MICROFLUIDIC CHANNEL; ON-SITE ANALYSIS; POINT-OF-CARE DIAGNOSTICS; SUBMILLIMETERS;

ORGANIC LIGHT EMITTING DIODES (OLED);

EID: 79551635866     PISSN: 19314973     EISSN: 19314981     Source Type: Journal    
DOI: 10.1002/tee.20630     Document Type: Article

References (13)

1. Heer F, Hafizovic S, Ugniwenko T, Frey U, Franks W, Perriard E, Perriard J-C, Blau A, Ziegler C, Hierlemann A. Single-chip microelectronic system to interface with living cells. Biosensors and Bioelectronics 2007; 22:2546-2553.
2. Lee H, Liu Y, Ham D, Westervelt RM. Integrated cell manipulation system-CMOS/microfluidic hybrid. Lab on a Chip 2007; 7:331-337.
3. Cui X, Lee LM, Heng X, Zhong W, Sternberg P-W, Psaltis D, Yang C. Lensless high-resolution on-chip optofluidic microscopes for Caenorhabditis elegans and cell imaging. Proceedings of the National Academy of Sciences of the United States of America 2008; 105(31):10670-10675.
4. Maruyama Y, Terao S, Sawada K. Label free CMOS DNA image sensor based on the charge transfer technique. Biosensors and Bioelectronics 2009; 24:3108-3112.
5. Adams ML, Enzelberger M, Quake S, Scherer A. Microfluidic integration on detector arrays for adsorption and fluorescence micro-spectrometers. Sensor and Actuater A 2003; 104:25-31.
6. Ren K, Liang Q, Yao B, Luo G, Wang L, Gao Y, Wang Y, Qiu Y. Whole column fluorescence imaging on a microchip by using a programmed organic light emitting diode array as a spatial-scanning light source and a single photomultiplier tube as detector. Lab on a Chip 2007; 7:1574-1580.
7. Richard C, Renaudin A, Aimez V, Charette PG. An integrated hybrid interference and absorption filter for fluorescence detection in lab-on-a-chip devices. Lab on a Chip 2009; 9:1371-1376.
8. Edel JB, Beard NP, Hofmann O, deMello JC, Bradley DD, deMello AJ. Thin-film polymer light emitting diodes as integrated excitation sources for microscale capillary electrophoresis. Lab on a Chip 2004; 4:136-140.
9. Tseng D, Mudanyali O, Oztoprak C, Isikman SO, Sencan I, Yaglidere O, Ozcan A. Lensfree microscopy on a cellphone. Lab on a Chip 2010; 10:1787-1792.
10. Tan W-H, Takeuchi S. A trap-and-release integrated microfluidic system for dynamic microarray applications. Proceedings of the National Academy of Sciences of the United States of America 2007; 104(4):1146-1151.
11. Krotkov E. Focusing. International Journal of Computer Vision 1987; 1:223-237.
12. Wee C-Y, Paramesran R. Measure of image sharpness using eigenvalues. Information Science 2007; 177:2533-2552.
13. Yamamura T, Kitamura M, Kuribayashi K, Arakawa Y, Takeuchi S. Flexible organic LEDs with parylene thin films for biological implants. MEMS2007, 2007, 739-742.