Role of ascorbate in lung cellular toxicity mediated by light-exposed parenteral nutrition solution

Free Radical Research

Volumn 45, Issue 3, 2011, Pages 359-365

  Nasef, Nehad ^a   Belcastro, Rosetta ^b   Nash, Andrea ^a   Bishara, Rosine ^a   Iaboni, Dolores ^a   Kantores, Crystal ^b   Keith Tanswell, A ^b,c,d   Jankov, Robert P ^a,c,d,e  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e Canada   (Canada)

Author keywords

hydroperoxides; hydroxyl radical; Oxidative stress

Indexed keywords

ADENINE; ASCORBIC ACID; CARBON 14; HYDROPEROXIDE DERIVATIVE; HYDROXYL RADICAL; MULTIVITAMIN; SCAVENGER;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FETUS; LIGHT EXPOSURE; LUNG INJURY; LUNG TOXICITY; NONHUMAN; PARENTERAL NUTRITION; RAT;

ANIMALS; ASCORBIC ACID; CELLS, CULTURED; EPITHELIAL CELLS; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; LIGHT; LUNG; PARENTERAL NUTRITION SOLUTIONS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 79551634080     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2010.532791     Document Type: Article

References (38)

1. Gitto E, Reiter RJ, Karbownik M, Tan DX, Gitto P, Barberi S, Barberi I. Causes of oxidative stress in the pre- and perinatal period. Biol Neonate 2002;81:146-157.
2. Lavoie JC, Chessex P. Gender and maturation affect glutathione status in human neonatal tissues. Free Radic Biol Med 1997;23:648-657.
3. Saugstad OD. Chronic lung disease: the role of oxidative stress. Biol Neonate 1998;74(Suppl 1):21-28.
4. Dani C, Cecchi A, Bertini G. Role of oxidative stress as physiopathologic factor in the preterm infant. Minerva Pediatr 2004;56:381-394.
5. Lavoie JC, Belanger S, Spalinger M, Chessex P. Admixture of a multivitamin preparation to parenteral nutrition: the major contributor to in vitro generation of peroxides. Pediatrics 1997;99:E6.
6. Laborie S, Lavoie JC, Pineault M, Chessex P. Contribution of multivitamins, air, and light in the generation of peroxides in adult and neonatal parenteral nutrition solutions. Ann Pharmacother 2000;34:440-445.
7. Chessex P, Harrison A, Khashu M, Lavoie JC. In preterm neonates, is the risk of developing bronchopulmonary dysplasia infl uenced by the failure to protect total parenteral nutrition from exposure to ambient light? J Pediatr 2007;151:213-214.
8. Bassiouny MR, Almarsafawy H, Abdel-Hady H, Nasef N, Hammad TA, Aly H. A randomized controlled trial on parenteral nutrition, oxidative stress, and chronic lung diseases in preterm infants. J Pediatr Gastroenterol Nutr 2009;48: 363-369.
9. Luo X, Christie NA, McLaughlin MA, Belcastro R, Sedlackova L, Cabacungan J, Freeman BA, Tanswell AK. H2O2 mediates O2 toxicity in cultured fetal rat distal lung epithelial cells. Free Radic Biol Med 1999;26:1357-1368.
10. Lavoie JC, Rouleau T, Tsopmo A, Friel J, Chessex P. Infl uence of lung oxidant and antioxidant status on alveolarization: role of light-exposed total parenteral nutrition. Free Radic Biol Med 2008;45:572-577.
11. Lavoie JC, Rouleau T, Chessex P. Interaction between ascorbate and light-exposed ribofl avin induces lung remodeling. J Pharmacol Exp Ther 2004;311:634-639.
12. Kim H, Kirschenbaum LJ, Rosenthal I, Riesz P. Photosensitized formation of ascorbate radicals by ribofl avin: an ESR study. Photochem Photobiol 1993;57:777-784.
13. Halliwell B. Vitamin C: antioxidant or pro-oxidant in vivo ? Free Radic Res 1996;25:439-454.
14. Laborie S, Lavoie JC, Chessex P. Paradoxical role of ascorbic acid and ribofl avin in solutions of total parenteral nutrition: implication in photoinduced peroxide generation. Pediatr Res 1998;43:601-606.
15. Lind SE, McDonagh JR, Smith CJ. Oxidative inactivation of plasmin and other serine proteases by copper and ascorbate. Blood 1993;82:1522-1531.
16. Wiswedel I, Trumper L, Schild L, Augustin W. Injury of mitochondrial respiration and membrane potential during iron/ ascorbate-induced peroxidation. Biochim Biophys Acta 1988;934:80-86.
17. Lavoie JC, Chessex P, Rouleau T, Migneault D, Comte B. Light-induced byproducts of vitamin C in multivitamin solutions. Clin Chem 2004;50:135-140.
18. Knafo L, Chessex P, Rouleau T, Lavoie JC. Association between hydrogen peroxide-dependent byproducts of ascorbic acid and increased hepatic acetyl-CoA carboxylase activity. Clin Chem 2005;51:1462-1471.
19. Zaniolo K, St-Laurent JF, Gagnon SN, Lavoie JC, Desnoyers S. Photoactivated multivitamin preparation induces poly- (ADPribosyl) ation, a DNA damage response in mammalian cells. Free Radic Biol Med 2010; 48: 1002-1012.
20. Lallemant C, Maghdessian R, Rouleau T, Lavoie JC. Urinary ascorbylperoxide: an early marker of bronchopulmonary dysplasia in preterm newborn. E-PAS 2010:34505.5.
21. Jiang ZY, Woollard AC, Wolff SP. Lipid hydroperoxide measurement by oxidation of Fe 2- in the presence of xylenol orange. Comparison with the TBA assay and an iodometric method. Lipids 1991;26:853-856.
22. Jiang ZY, Woollard AC, Wolff SP. Hydrogen peroxide production during experimental protein glycation. FEBS Lett 1990;268:69-71.
23. Lavoie JC, Lachance C, Chessex P. Antiperoxide activity of sodium metabisulfi te. A double-edged sword. Biochem Pharmacol 1994;47:871-876.
24. Luo X, Belcastro R, Cabacungan J, Hannam V, Negus A, Wen Y, Plumb J, Hu J, Steer B, Koehler DR, Downey GP, Tanswell AK. Transfection of lung cells in vitro and in vivo: effect of antioxidants and intraliposomal bFGF. Am J Physiol Lung Cell Mol Physiol 2003;284:817-825.
25. Tanswell AK, Staub O, Iles R, Belcastro R, Cabacungan J, Sedlackova L, Steer B, Wen Y, Hu J, O'Brodovich H. Liposome- mediated transfection of fetal lung epithelial cells: DNA degradation and enhanced superoxide toxicity. Am J Physiol 1998;275:452-460.
26. Shirhatti V, Krishna G. A simple and sensitive method for monitoring drug-induced cell injury in cultured cells. Anal Biochem 1985;147:410-418.
27. Olafsdottir K, Ryrfeldt A, Atzori L, Berggren M, Moldeus P. Hydroperoxide-induced broncho- and vasoconstriction in the isolated rat lung. Exp Lung Res 1991;17:615-627.
28. Videla LA, Villena MI, Salgado C, Canales P, Lissi EA. Antioxidant capacity of desferrioxamine in biological systems. Biochem Int 1987;15:205-214.
29. Persson HL, Yu Z, Tirosh O, Eaton JW, Brunk UT. Prevention of oxidant-induced cell death by lysosomotropic iron chelators. Free Radic Biol Med 2003;34:1295-1305.
30. Silvers KM, Sluis KB, Darlow BA, McGill F, Stocker R, Winterbourn CC. Limiting light-induced lipid peroxidation and vitamin loss in infant parenteral nutrition by adding multivitamin preparations to Intralipid. Acta Paediatr 2001;90: 242-249.
31. Kortenkamp A, O'Brien P. The generation of DNA singlestrand breaks during the reduction of chromate by ascorbic acid and/or glutathione in vitro . Environ Health Perspect 1994;102(Suppl 3):237-241.
32. Poljsak B, Gazdag Z, Jenko-Brinovec S, Fujs S, Pesti M, Belagyi J, Plesnicar S, Raspor P. Pro-oxidative vs antioxidative properties of ascorbic acid in chromium(VI)-induced damage: an in vivo and in vitro approach. J Appl Toxicol 2005;25:535-548.
33. Stearns DM, Kennedy LJ, Courtney KD, Giangrande PH, Phieffer LS, Wetterhahn KE. Reduction of chromium(VI) by ascorbate leads to chromium-DNA binding and DNA strand breaks in vitro . Biochemistry 1995;34:910-919.
34. Buettner GR, Jurkiewicz BA. Ascorbate free radical as a marker of oxidative stress: an EPR study. Free Radic Biol Med 1993;14:49-55.
35. Wolff SP, Wang GM, Spector A. Pro-oxidant activation of ocular reductants. 1. Copper and ribofl avin stimulate ascorbate oxidation causing lens epithelial cytotoxicity in vitro . Exp Eye Res 1987;45:777-789.
36. Yin H, Porter NA. Specifi city of the ferrous oxidation of xylenol orange assay: analysis of autoxidation products of cholesteryl arachidonate. Anal Biochem 2003;313:319-326.
37. Kramarenko GG, Wilke WW, Dayal D, Buettner GR, Schafer FQ. Ascorbate enhances the toxicity of the photodynamic action of Verteporfi n in HL-60 cells. Free Radic Biol Med 2006;40:1615-1627.
38. Peterkofsky B, Prather W. Cytotoxicity of ascorbate and other reducing agents towards cultured fi broblasts as a result of hydrogen peroxide formation. J Cell Physiol 1977;90: 61-70.