Anxiolytic-like effects of standardized extract of Justicia pectoralis (SEJP) in mice: Involvement of GABA/benzodiazepine in receptor

Phytotherapy Research

Volumn 25, Issue 3, 2011, Pages 444-450

  Venancio E T ^a   Rocha, N F M ^a   Rios, E R V ^a   Feitosa, M L ^a   Linhares, M I ^a   Melo, F H C ^a   Matias, M S ^a   Fonseca, F N ^a   Sousa, F C F ^a   Leal, L K A M ^a   Fonteles, Marta Maria De França ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Anxiolytic effect; GABAA receptor; Justicia pectoralis; Sedative effect; SEJP; Standardized extract

Indexed keywords

4 AMINOBUTYRIC ACID; BENZODIAZEPINE; BENZODIAZEPINE RECEPTOR; DIAZEPAM; FLUMAZENIL; JUSTICIA PECTORALIS EXTRACT; PENTOBARBITAL; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG;

ACANTHACEAE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIORAL SCIENCE; CONTROLLED STUDY; DRUG EFFECT; JUSTICIA PECTORALIS; LIGHT DARK CYCLE; MALE; MOUSE; NONHUMAN; SINGLE DRUG DOSE; SLEEP TIME; TRANQUILIZING ACTIVITY;

ACANTHACEAE; ANIMALS; ANTI-ANXIETY AGENTS; BEHAVIOR, ANIMAL; MALE; MAZE LEARNING; MICE; PLANT EXTRACTS; RECEPTORS, GABA-A;

ACANTHACEAE; ANIMALIA; JUSTICIA PECTORALIS; MUS;

EID: 79551627498     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3274     Document Type: Article

References (43)

1. Amos S, Kolawole E, Akah P, Wambebe C, Gamaniel K. 2001. Behavioral effects of the aqueous extract of Guiera senegalensis in mice and rats. Phytomedicine 8: 356-361. (Pubitemid 32983055)
2. Archer J. 1973. Tests for emotionality in rats and mice: a review. Animal Behav 21: 205-235.
3. Barbosa PR, Valvassori SS, Bordignon CLJ et al. 2008. The aqueous extracts of Passiflora alata and Passiflora edulis reduce anxiety-related behaviors without affecting memory process in rats. J Med Food 11: 282-288. (Pubitemid 351948187)
4. Barnett SA. 1963. The Rat: A Study in Behavior. Methuen: London.
5. Barros RFM. 1992. Efeito da radiação solar sobre o crescimento e produção de cumarinas em Justicia pectoralis, Jacq. var. Stenophylla Leonard. Dissertação (Mestrado em Botânica). Universidade Federal de Pernambuco: Recife, 143p.
6. Bourin M, Hascoët M. 2003. The mouse light/dark box test. Eur J Pharmacol 463: 55-65. (Pubitemid 36205072)
7. Chanfrau JER, Hernández ODL, Apan JMG. 2008. Method for coumarin quantification in dry extracts from Justicia pectoralis Jacq. Rev Cub Plantas Med 13(3) Jul.-Sept.: 0-0.
8. Chariandy CM, Seaforth CE, Phelps RH, Pollard GV, Khambay BPS. 1999. Screening of medicinal plants from Trinidad and Tobago for antimicrobial and insecticidal properties. J Ethnopharmacol 64: 265-270. (Pubitemid 29170213)
9. Correa PM. 1984. Dicionário de Plantas Úteis do Brasil e das Exóticas Cultivadas, vol. 5. Ministério da Agricultura, Instituto Brasileiro de Desenvolvimento: Florestal, Brazil, 474-475.
10. Crawley JN, Goodwin FK. 1980. Preliminary report of a simple animal behavior for the anxiolytic effects of benzodiazepines. Pharmacol Biochem Behav 13: 167-170. (Pubitemid 11225713)
11. de Vries JX, Tauscher B,Wurzel G. 1988. Constituents of Justicia pectoralis, Jacq. 2. Gas chromatography/mass spectrometry of simple coumarins, 3-phenylpropionic acids and their hydroxy and methoxy derivatives. Biomed Environ Mass Spectrom 15: 413-417.
12. Dunham NW, Miya TS. 1957. A note on a simple apparatus for detecting neurological deficits in rats and mice. J AmPharm Assoc 46: 208.
13. Fernández L, Pérez H, Más R. 1989. Evaluación preliminar de los efectos neurofarmacológicos de la Justicia pectoralis Jacq. Rev Cub Farm 23: 161-166. (Pubitemid 20169886)
14. Fonseca FN, Moura RR, Moura LMR, Viana GSB, Leal LKAM. 2007. Development, validation and HPLC analysis of coumarin and 7-hydroxycoumarin in Justicia pectoralis extract T. In 6th International Congress of Pharmaceutical Sciences (CIFARP). Ribeirão Preto, São Paulo, Brazil.
15. Leal LKAM, Ferreira AAG, Bezerra GA, Matos FJA, Viana GSB. 2000 Antinociceptive, anti-inflammatory and bronchodilator activities of Brazilian medicinal plants containing coumarin: a comparative study. J Ethnopharmacol 70: 151-159. (Pubitemid 30193241)
16. Lilly SM, Tietz EI. 2000. Chronic cocaine differentially affects diazepam's anxiolytic and anticonvulsant actions. Relationship to GABA(A) receptor subunit expression. Brain Res 882: 139-148.
17. Lino CS, Viana GSB, Matos FJA. 1997. Analgesic and antiinflammatory activities of Justicia pectoralis Jacq. and its constituents: coumarin and umbelliferone. Phytother Res 11: 211-215. (Pubitemid 27193218)
18. Lister RG. 1987. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology 92: 180-185. (Pubitemid 17072893)
19. Macrae WD, Towers GHN. 1984. Justicia pectoralis: a study of the basis for its use as a hallucinogenic snuff ingredient. J Ethnopharmacol 12: 93-111. (Pubitemid 14046621)
20. Melo CTV, Monteiro AP, Leite CP et al. 2006. Anxiolytic-like effects of (O-methyl)-N-2,6-dihydroxybenzoyl-tyramine (Riparin III) from Aniba riparia (Nees) MEZ (Lauraceae) in mice. Biol Pharm Bull 29: 451-454.
21. Melo FHC, Venancio ET, De Sousa DP et al. 2010. Anxiolytic-like effect of carvacrol (5-isopropyl-2-methylphenol) in mice: involvement with GABAergic transmission. Fund Clin Pharmacol 24(4): 437-443.
22. Mills J, Pascoe KO, Chambers J et al. 1986. Preliminary investigations of the wound-healing properties of a Jamaica folk medicinal plant (Justicia pectoralis). West Indian Med J Kingston 35: 190-193.
23. Montgomery KC. 1958. The relation between fear induced by novel stimulation and exploratory behavior. J Comp Physiol Psychol 48: 254-260.
24. Novas ML, Wolfman C, Medina JH, De Robertis E. 1988. Proconvulsant and 'anxiogenic' effects of n-butyl beta carboline-3-carboxylate, in endogenous benzodiazepine binding inhibitor from brain. Pharmacol Biochem Behav 30: 331-336. (Pubitemid 19264236)
25. value) in mice, to determine oral acute toxicity of plant extracts. Phytomedicine 8: 395-400.
26. Pellow S, Chopin P, File SE, Briley M. 1985. Validation of open: closed arm entries in an elevated plus maze as a measure of anxiety in the rat. J Neurosci Methods 14: 149-167. (Pubitemid 16239568)
27. Pereira EC, Lucetti DL, Barbosa-Filho JM et al. 2009. Coumarin effects on amino acid levels in mice prefrontal cortex and hippocampus. Neurosci Lett 454: 139-142.
28. Rabbani M, Sajjadi SE, Mohammadi A. 2007. Evaluation of the anxiolytic effect of Nepeta persica Boiss. in mice. Advance Access Publication 5(2): 181-186.
29. Rodgers RJ, Cao BJ, Dalvi A, Holmes A. 1997. Animal models of anxiety on ethological perspective. Braz J Med Biol Res 30: 289-304. (Pubitemid 127521025)
30. Rodríguez E, Virvés A, Alemán C. 1989. Estudio preliminar del efecto de la Justicia pectoralis sobre el EEG de adultos normales. Rev Cub Farm 23: 302-308.
31. Rolland A, Fleurentin J, Lanhers MC et al. 1991. Behavioural effects of the American traditional plant Eschscholzia californica: sedative and anxiolytic properties. Planta Med 57: 212-216.
32. Silva MIG, Neto MRA, Neto PFT et al. 2007. Central nervous system activity of acute administration of isopulegol in mice. Pharmacol Biochem Behav 88: 141-147. (Pubitemid 350115997)
33. Sousa FCF, Melo CTV, Cito MCO et al. 2008. Plantas medicinais e seus constituintes bioativos: Uma revisão da bioatividade e potenciais benefícios nos distúrbios da ansiedade em modelos animais. Braz J Pharmacogn 18: 642-654.
34. Sousa FCF, Monteiro AP, Melo CTV et al. 2005a. Antianxiety effects of Ripani I from Aniba riparia (Nees) Mez (Lauraceae) in mice. Phytother Res 19: 1005-1008.
35. Sousa FCF, Pereira BA, Lima VT et al. 2005b. Central nervous system activity of yangambin from Ocotea duckei Vattimo (Lauraceae) in mice. Phytother Res 19: 282-286. (Pubitemid 41098119)
36. Taveira ML. 1993. Contribuição ao conhecimento químico de plantas do Nordeste: J. pectoralis, Jacq. var. Stenophylla Leonard (Acanthaceae) e Bombax cearens. Ducke (Bombacaceae). Master Thesis. Department of Organic Chemistry, Federal University of Ceara: Fortaleza, 140.
37. Tolardo R, Zetterman L, Bitencourtt D et al. 2010. Evaluation of behavioral and pharmacological effects of Hedyosmum brasiliense and isolated sesquiterpene lactones in rodents. J Ethnopharmacol 128: 63-70.
38. Treit D, Fundytus M. 1988. Thigmotaxis as a test for anxiolytic activity in rats. Pharmacol Biochem Behav 31: 959-962. (Pubitemid 19274312)
39. Treit D, Menard J, Royan C. 1993. Anxiogenic stimuli in the elevated plus-maze. Pharmacol Biochem Behav 44: 463-469.
40. Wambebe C. 1985. Influence of some agents that affect 5-hydroxy-tryptamine metabolism and receptors on nitrazepam-induced sleep in mice. Braz J Pharmacol 84: 185-191. (Pubitemid 15169070)
41. WHO. 2001. The World Health Report. Mental Health: New Understanding New Hope. Geneva: WHO.
42. Willianson E, Okpako D, Evans FJ. 1996. Selection, Preparation and Pharmacological Evaluation of Plant Material. Wiley: Chichester.
43. Zarrindast MR, Babapoor-Farrokhran S, Babapoor-Farrokhran S, Rezayof A. 2008. Involvement of opioidergic system of the ventral hippocampus, the nucleus accumbens or the central amygdala in anxiety-related behavior. Life Sci 82: 1175-1181.