Have the efforts to prevent aspirin-related Reye's syndrome fuelled an increase in asthma?

Clinical and Experimental Allergy

Volumn 41, Issue 3, 2011, Pages 296-298

  Johnson, C C ^a   Ownby, D R ^b  

^a HENRY FORD HOSPITAL   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 2; PARACETAMOL; PROSTAGLANDIN E2;

ASTHMA; CAUSAL ATTRIBUTION; CHILD; DRUG EFFECT; DRUG EXPOSURE; EDITORIAL; HUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REYE SYNDROME; RISK FACTOR; TH2 CELL;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; ASTHMA; HUMANS; REYE SYNDROME;

EID: 79551615763     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2010.03683.x     Document Type: Editorial

References (20)

1. Wickens K, Beasley R, Town I et al. The effects of early and late paracetamol exposure on asthma and atopy: a birth cohort. Clin Exp Allergy 2011; 41:399-406.
2. Persky VW. Acetaminophen and asthma. Thorax 2010; 65:99-100.
3. Kang EM, Lundsberg LS, Illuzzi JL, Bracken MB. Prenatal exposure to acetaminophen and asthma in children. Obstet Gynecol 2009; 114:1295-306.
4. Belay ED, Bresee JS, Holman RC, Khan AS, Shahriari A, Schonberger LB. Reye's syndrome in the United States from 1981 through 1997. N Engl J Med 1999; 340:1377-82.
5. Newson RB, Shaheen SO, Chinn S, Burney PG. Paracetamol sales and atopic disease in children and adults: an ecological analysis. Eur Respir J 2000; 16:817-23.
6. Nuttall SL, Khan JN, Thorpe GH, Langford N, Kendall MJ. The impact of therapeutic doses of paracetamol on serum total antioxidant capacity. J Clin Pharm Ther 2003; 28:289-94.
7. Varner A. Paracetamol and asthma. Thorax 2000; 55:882-3.
8. Lawyer AB. Paracetamol as a risk factor for allergic disorders. Lancet 2009; 373:121.
9. Rothman KJ, Greenland S. Precision and validity in epidemiologic studies. In: Rothman KJ, Greenland S, eds. Modern epidemiology, 2nd Edn. Philadelphia: Lippincott-Raven, 1998; 115-34.
10. Perzanowski MS, Miller RL, Tang D et al. Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort. Thorax 2010; 65:118-23.
11. Hill AB. The environment and disease: association or causation? Proc R Soc Med 1965; 58:295-300.
12. Beasley R, Clayton T, Crane J et al. Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from phase three of the ISAAC programme. Lancet 2008; 372:1039-48.
13. Davey G, Berhane Y, Duncan P, ref-Adib G, Britton J, Venn A. Use of acetaminophen and the risk of self-reported allergic symptoms and skin sensitization in Butajira, Ethiopia. J Allergy Clin Immunol 2005; 116:863-8.
14. McKeever TM, Lewis SA, Smit HA, Burney P, Britton JR, Cassano PA. The association of acetaminophen, aspirin, and ibuprofen with respiratory disease and lung function. Am J Respir Crit Care Med 2005; 171:966-71.
15. Shaheen SO, Sterne JA, Songhurst CE, Burney PG. Frequent paracetamol use and asthma in adults. Thorax 2000; 55:266-70.
16. Etminan M, Sadatsafavi M, Jafari S, Doyle-Waters M, Aminzadeh K, FitzGerald JM. Acetaminophen use and the risk of asthma in children and adults: a systematic review and metaanalysis. Chest 2009; 136:1316-23.
17. Tapiainen T, Dunder T, Mottonen M, Pokka T, Uhari M. Adolescents with asthma or atopic eczema have more febrile days in early childhood: a possible explanation for the connection between paracetamol and asthma? J Allergy Clin Immunol 2010; 125:751-2.
18. Barr RG. Does paracetamol cause asthma in children? Time to remove the guesswork. Lancet 2008; 372:1011-2.
19. Farquhar H, Stewart A, Mitchell E et al. The role of paracetamol in the pathogenesis of asthma. Clin Exp Allergy 2010; 40:32-41.
20. Pierce CA, Voss B. Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review. Ann Pharmacother 2010; 44:489-506.