The influence of vitamin D derivatives on the expression of apoptotic genes in nasal polyp fibroblasts

Advances in Clinical and Experimental Medicine

Volumn 19, Issue 6, 2010, Pages 679-684

  Fra̧czek, Marcin ^a   Rostkowska Nadolska, Beata ^a   Sliupkas Dyrda, Elektra ^b   Kuśmierz, Dariusz ^a   Pniak, Jakub ^b   Latocha, Małgorzata ^b  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Apoptosis; Calcitriol; ELISA; Immunohistochemistry; Nasal polyps; QRT PCR; Tacalcitol

Indexed keywords

CALCITRIOL; PROTEIN BAX; PROTEIN BCL 2; TACALCITOL; VITAMIN D DERIVATIVE;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL DIVISION; CELL PROLIFERATION; CLINICAL ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NOSE POLYP; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHINOSINUSITIS;

EID: 79551604422     PISSN: 1230025X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Pawankar R: Nasal polyposis: an update. Curr Opin Allergy Clin Immunol 2003, 3, 1-6.
2. Mullol J: Trends on rhinosinusitis diagnosis and treatment. Otolaryngol Pol 2009, 63(7), 3-4.
3. Rostkowska-Nadolska B, FraczekM, Gawron W, Latocha M: Influence of vitamin D3 analogues in combination with budesonid R on proliferation of nasal polyp fibroblasts Acta Biochim Pol 2009, 56(2), 235-242.
4. Verstuyf A, Carmeliet G, Bouillon R, Mathieu C: Vitamin D: a pleiotropic hormone. Kidney Int 2010, 78(2), 140-145.
5. MacDonald PN, Baudino TA, Tokumaru H, Dowd DR, Zhang C: Vitamin D receptor and nuclear receptor coactivators: crucial interactions in vitamin D-mediated transcription. Steroids 2001, 66(3-5), 171-176.
6. Johnson CS, Hershberger PA, Bernardi RJ, Mcguire TF, Trump DL: Vitamin D receptor: a potential target for intervention. Urology 2002, 60 (Suppl 1), 123-130.
7. Plataki M, Koutsopoulos AV, Darivianaki K, Delides G, Siafakas NM, Bouros D: Expression of apoptotic and anti-apoptotic markers in epithelial cells in idiopathic pulmonary fibrosis. Chest 2005, 127(1), 266-274.
8. Yang T, Buchan HL, Townsend KJ, Craig RW: MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation. J Cell Physiol 1996, 166(3), 523-536.
9. Adams JM, Cory S: The Bcl-2 protein family: arbiters of cell survival. Science 1998, 281, 1322-1326.
10. Sedlak TW, Oltvai ZN, Yang E, Wang K, Boise LH, Thompson CB, Korsmeyer S: Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci USA 1995, 92, 7834-7838.
11. Ruiz-Vela A, Korsmeyer SJ: Pro-apoptotic histone H1.2 induces CASP-3 and -7 activation by forming a protein complex with CYT c, APAF-1 and CASP-9. FEBS Lett 2007, 24, 581(18), 3422-3428.
12. Malloy PJ, Feldman D: Inactivation of the human vitamin D receptor by caspase-3. Endocrinology 2009, 150(2), 679-686.
13. Guzey M, Kitada S, Reed JC: Apoptosis induction by 1,25-dihydroxyvitamin D3 in prostate cancer. Mol Cancer Ther 2002, 1, 667-672.
14. Narvaez CJ, Welsh J: Role of mitochondria and caspases in vitamin D-mediated apoptosis of MCF-7 breast cancer cells. J Biol Chem 2001, 23, 9101-9108.
15. Diaz GD, Paraskeva C, Thomas MG, Binderup L, Hague A: Apoptosis is induced by the active metabolite of Vitamin D3 and its analogue EB1089 in colorectal adenoma and carcinoma cells: possible implications for prevention and therapy. Cancer Res 2000, 60, 2304-2312.
16. Kizildag S, Ates H, Kizildag S: Treatment of K562 cells with 1,25-dihydroxyvitamin D(3) induces distinct alterations in the expression of apoptosis-related genes BCL2, BAX, BCL(XL), and p21. Ann Hematol 2009, 89, 1-7.
17. Flynn G, Chung I, Yu W-D, Romano M, Modzelewski RA: Calcitriol (1,25-Dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis. Oncology 2006, 70, 447-457.
18. Elstner E, Linker-Israeli M, Le J, Umiel T, Michl P, Said JW, Binderup L, Reed JC, Koeffler HP: Synergistic decrease of clonal proliferation, induction of differentiation, and apoptosis of acute promyelocytic leukemia cells after combined treatment with novel 20-epivitamin D3 analogs and 9-cis retinoic acid. J Clin Invest 1997, 99, 349-360.
19. Blutt SE, McDonnell TJ, Polek TC, Weigel N: Calcitriolinduced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2. Endocrinology 2000, 141, 10-17.
20. Sabet SJ, Darjatmoko SR, Lindstrom MJ, Albert DM: Antineoplastic effect and toxicity of 1,25-dihydroxy-16-ene-23-ynevitamin D3 in athymic mice with Y79 human retinoblastoma tumors. Arch Ophthalmol 1999, 117, 365-370.
21. Tanghetti EA: The role of topical vitamin D modulators in psoriasis therapy. J Drugs Dermatol 2009, 8, 4-8.
22. James SY, Morse E, Brady M, Binderup L, Colster KW: EB1089, a synthetic analogue of vitamin D, induces apoptosis in breast cancer cells in vivo and in vitro. Eur J Pharmacol 1998, 125, 953-962.
23. Kimura Y, Sugimoto C, Takabayashi T, Tanaka T, Kojima A, Narita N, Fujieda S: Bax-gene transfer enhances apoptosis by steroid treatment in human nasal fibroblasts. Eur Arch Otorhinolaryngol 2009, 7, 28-33.
24. James S, Mackay AG, Colston KW: Effects of 1,25 dihydroxyvitamin D3 and its analogues on induction of apoptosis in breast cancer cells. Mol Biol 1996, 58, 395-401.
25. Elstner E, Linker-Israeli M, Said J, Umiel T, de Vos S, Shintaku IP, Heber D, Binderup L, Uskokovic M, Koeffler HP: 20-epi-vitamin D3 analogues: a novel class of potent inhibitors of proliferation and inducers of differentiation of human breast cancer cell lines. Cancer Res 1995, 55, 2822-2830.
26. Zhuang SH, Burnstein KL: Antiproliferative effect of 1alpha,25- dihydroxyvitamin D3 in human prostate cancer cell line LNCaP involves reduction of cyclin-dependent kinase 2 activity and persistent G1 accumulation. Endocrinology 1998, 139(3), 1197-1207.