Vitamin D and health status in elderly

Internal and Emergency Medicine

Volumn 6, Issue 1, 2011, Pages 11-21

  Timpini, Annalisa ^a   Pini, Laura ^a   Tantucci, Claudio ^a   Cossi, Stefania ^a   Grassi, Vittorio ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Chronic diseases; Elderly; Vitamin D; Vitamin D receptors

Indexed keywords

CALCITRIOL RECEPTOR; VITAMIN D;

AGED; CHRONIC DISEASE; FEMALE; HEALTH STATUS; HUMAN; MALE; REVIEW; VITAMIN D DEFICIENCY;

AGED; AGED, 80 AND OVER; CHRONIC DISEASE; FEMALE; HEALTH STATUS; HUMANS; MALE; RECEPTORS, CALCITRIOL; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 79551599366     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-010-0407-4     Document Type: Review

References (55)

1. Brannon PM, Yetley EA, Bailey RL, Picciano MF (2008) Overview of the conference "Vitamin D and health in the 21st century: an update". Am J Clin Nutr 88: 483S-490S.
2. Holick MF (2007) Vitamin D deficiency. N Engl J Med 357: 266-281.
3. Bikle D (2009) Nonclassic actions of vitamin D. J Clin Endocrinol Metab 94: 26-34.
4. Holick MF (2006) High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc 81: 353-373.
5. Hollis BW (2005) Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effective dietary intake recommendation for vitamin D. J Nutr 135: 317-322.
6. Giovannucci E (2009) Expanding role of vitamin D. J Clin Endocrinol Metab 94: 418-420.
7. Bouillon R, Carmeliet G, Verlinden L et al (2008) Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev 29: 726-776.
8. Hyppönen E, Läärä E, Reunanen A, Järvelin MR, Virtanen SM (2001) Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet 358: 1500-1503.
9. Adams JS, Liu PT, Chun R, Modlin RL, Hewison M (2007) Vitamin D in defence of the human immune response. Ann NY Acad Sci 1117: 94-105.
10. von Essen MR, Kongsbak M, Schjerhing P, Olgaard K, Odun M, Geider C (2010) Vitamin D controls T cell antigen receptor signaling and activation of human cells. Nat Immunol. doi: 10. 1038/ni. 1851.
11. Vieth R, Ladak Y, Walfish PG (2003) Age related changes in the 25(OH)D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D. J Clin Endocrinol Metab 88: 185-191.
12. Maggio D, Cherubini A, Lauretani F et al (2005) 25(OH)D serum levels decline with age earlier in women than in men and less efficiently prevent compensatory hyperparathyroidism in older adults. J Gerontol A Biol Sci Med Sci 60: 1414-1419.
13. Heaney RP (2003) Long-latency deficiency disease: insights from calcium and vitamin D. Am J Clin Nutr 78: 912-919.
14. Timpini A, Cossi S, Bugari G et al (2009) Vitamin D: an observational study in elderly. Biochim Clin 33: 533-538.
15. Isaia G, Giorgino R, Rini GB, Bevilacqua M, Maugeri D, Adami S (2003) Prevalence of hypovitaminosis D in elderly women in Italy: clinical consequences and risk factors. Osteoporos Int 14: 577-582.
16. van der Wielen RP, Lovik MRH, van der Berg H et al (1995) Serum vitamin D concentrations among elderly people in Europe. Lancet 346: 207-210.
17. Kuchuk NO, Vanschoor NM, Pluijm SM, Chines A, Lips P (2009) Vitamin D status, parathyroid function, bone turnover and BMD in postmenopausal women with osteoporosis: global perspective. J Bone Miner Res 24: 693-701.
18. Dawson-Hughes B (2008) Serum 25-hydroxyvitamin D and function outcomes in the elderly. Am J Clin Nutr 88: 5375-5405.
19. Mosekilde L (2005) Vitamin D and the elderly. Clin Endocrinol 62: 265-281.
20. Shardell M, Hicks GE, Miller RR, Kritchevsky S, Anderson D, Bandinelli S, Cherubini A, Ferrucci L (2009) Association of low vitamin D levels with the frailty syndrome in men and women. J Gerontol A Biol Sci Med Sci 64A: 69-75.
21. Vonhurst PR, Stonehouse W, Cood J (2010) Vitamin D supplementation reduces insulin resistance in South Asian women living in New Zealand who are insulin resistant and vitamin deficient. A randomized, Placebo controlled trial. Br J Nutr 103: 549-555.
22. Ceglia L (2008) Vitamin D and skeletal muscle tissue and function. Mol Aspect Med 29: 407-414.
23. Trivedi DP, Doll R, Khaw KT (2003) Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. BMJ 326: 469-474.
24. Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB et al (2009) Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. BMJ 339: b3692. doi: 10. 1136/bmj. b3692.
25. Bischoff-Ferrari HA, Willett WC, Wong JB et al (2009) Prevention of non-vertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomised controlled trials. Arch Intern Med 169: 551-561.
26. Mazziotti G, Angeli A, Bilezikian JP, Canalis E, Giustina A (2006) Glucocorticoid-induced osteoporosis: an update. Trends Endocrinol Metab 17: 144-149.
27. Barone A, Giusti A, Pioli G et al (2007) Secondary hyperparathyroidism due to hypovitaminosis D effects BMD response to alendronate in elderly women with osteoporosis: a randomized controlled trial. J Am Geriatr Soc 55: 752-757.
28. Toussaint ND, Kerr PG (2007) Vascular calcification and arterial stiffness in chronic kidney disease: implication and management. Nephrology 12: 500-509.
29. Zehnder D, Quinkler M, Eardley KS et al (2008) Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation. Kidney Int 74: 1343-1353.
30. Fleet M, Osman F, Komaragiri R, Fritz AD (2008) Protein catabolism in advanced renal disase: role of cytokines. Clin Nephrol 70: 91-100.
31. Wilke RA, Simpson RU, Mukesh BN, Bhupathi SV, Dart RA, Ghebranious NR, McCarty CA (2009) Genetic variation in CYP27B1 is associated with congestive heart failure in patients with hypertension. Pharmacogenomics 10: 1789-1797.
32. Schleithoff SS, Zittermann A, Tenderich G, Berthold HK, Stehle P, Koerfer R (2006) Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 83: 754-759.
33. Giovannucci E, Liu Y, Hollis BW, Rimm EB (2008) 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med 168: 1174-1180.
34. Tarcin O, Yavuz DG, Ozben B, Telli A, Ogunc AV, Yuksel M, Toprak A, Yazici D, Sancak S, Deyneli O, Akalin S (2009) Effect of vitamin D deficiency and replacement on endothelial function in asymptomatic subjects. J Clin Endocrinol Metab 94: 4023-4030.
35. Hagström E, Hellman P, Larsson TE, Ingelsson E, Berglund L, Sundström J, Melhus H, Held C, Lind L, Michaëlsson K, Arnlöv J (2009) Plasma parathyroid hormone and the risk of cardiovascular mortality in the community. Circulation 119: 2765-2771.
36. Pilz S, Tomaschitz A, Ritz E, Pieber TR (2009) Vitamin D status and arterial hypertension: a systematic review. Nat Rev Cardiol 6: 621-630.
37. Judd SE, Nanes MS, Ziegler TR, Wilson PWF, Tangpricha W (2008) Optimal Vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: results from the third National Health and Nutrition Examination Survey. Am J Clin Nutr 87: 136-141.
38. Black PN, Scragg R (2005) Relationship between serum 25-hydroxyvitamin D and pulmonary function in the third national health and nutrition examination survey. Chest 128: 3792-3798.
39. Janssens W, Lehouck A, Carremans C, Bouillon R, Matthieu C, Decramer M (2009) Vitamin D beyond bones in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 179: 630-636.
40. Sutherland ER, Goleva E, Jackson LP, Stevens AD, Leung DYM (2010) Vitamin D levels, lung function and steroid response in adult asthma. Am J Respis Crit Care Med. doi: 10. 1164/rccm200911-1710OC.
41. Norman AW, Frankel JB, Hekdt AM et al (1980) Vitamin D deficiency inhibits pancreatic secretion of insulin. Science 209: 823-825.
42. Pittas AG, Lan J, Huf F, Dawson-Huglies B (2007) Review: the role of vitamin D and calcium in type 2 diabetes. Asystematic review and meta-analysis. J Clin Endocrinol Metab 92: 2017-2029.
43. Shoelson SE, Loe J, Goldfine AB (2006) Inflammation and insulin resistance. J Clin Invest 116: 1793-1801.
44. Cigolini M, Iagulli MP, Miconi V et al (2006) Serum 25-hydroxyvitamin D3 concentration and prevalence of cardiovascular disease among type 2 diabetic patients. Diabetes Care 29: 722-724.
45. Oh J, Weng S, Felton SK et al (2009) 1, 25(OH)2D inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus. Circulation 120: 687-698.
46. Kostner K, Denzer N, Muller CS et al (2009) The relevance of vitamin D receptor (VDR) gene polymorphism for cancer: a review of the literature. Anticancer Res 29: 3511-3536.
47. Mohr SB (2009) A brief history of vitamin D and cancer prevention. Ann Epidemiol 19: 79-83.
48. Freedman DM, Looker AC, Chang SC, Graubard BI (2007) Prospective study of serum vitamin D and cancer mortality in the United States. J Natl Cancer Inst 99: 1594-1602.
49. Janab M, Bueno-de-Mesquite HB, Ferrarri P et al (2010) Association between pre-diagnostic circulating vitamin D concentration and risk of colo-rectal cancer in European populations: a nested case-control study. BMJ 340: b5500. doi: 10. 1136/bmj. b5500.
50. Eyles DW, Smith S, Kinobe R, Hewison M, McGrath JJ (2005) Distribution of vitamin D receptor and 1 alpha-hydroxylase in human brain. J Chem Neuroanat 29: 21-30.
51. McCann JC, Ames BN (2008) Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction? FASEB J 22: 982-1001.
52. Annweller C, Schott AM, Allali G et al (2010) Association of vitamin D deficiency with cognitive impairment in older women: cross-sectional study. Neurology 74: 27-32.
53. Autier Ph, Gandini S (2007) Vitamin D supplementation and total mortality. A meta-analysis of randomised controlled trials. Arch Int Med 167: 1730-1737.
54. Semba RD, Houston DR, Bandinelli S, Ferrucci L, et al (2009) Relationship of 25-hydroxyvitamin D with all-cause and cardiovascular disease mortality in older community-dwelling adults. Eur J Clin Nutr. doi: 10: 1038/ejcn. 2009. 140.
55. Hathock JN, Shao A, Vieth R, Heaney R (2007) Risk assessment for vitamin D. Am J Clin Nutr 85: 6-18.