A new stochastic approach to multi-compartment pharmacokinetic models: Probability of traveling route and distribution of residence time in linear and nonlinear systems

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 38, Issue 1, 2011, Pages 83-104

  Zhao, Liang ^a   Li, Na ^b   Yang, Harry ^b  

^a OHIO STATE UNIVERSITY   (United States)

^b MEDIMMUNE   (United States)

Author keywords

Compartment expansion; Multi compartment model; Nonlinear systems; Pharmacokinetics; Stochastic Markovian model

Indexed keywords

ARTICLE; COMPARTMENT MODEL; CONCEPTUAL FRAMEWORK; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG EXPOSURE; DRUG RESEARCH; DRUG SAFETY; LINEAR SYSTEM; MEAN RESIDENCE TIME; METHODOLOGY; NONLINEAR SYSTEM; PRIORITY JOURNAL; PROBABILITY; STOCHASTIC MODEL;

HUMANS; KINETICS; LINEAR MODELS; MODELS, BIOLOGICAL; MODELS, STATISTICAL; NONLINEAR DYNAMICS; PHARMACOKINETICS; PROBABILITY; STOCHASTIC PROCESSES; TIME FACTORS;

EID: 79551577102     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-010-9179-8     Document Type: Article

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