Using stochastic differential equations for PK/PD model development

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 32, Issue 1, 2005, Pages 109-141

  Kristensen, Niels Rode ^a   Madsen, Henrik ^b   Ingwersen, Steen Hvass ^a  

^a NOVO NORDISK A S   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Extended Kalman filtering; Nonparametric modelling; Parameter estimation; Random walk; Smoothing; Stochastic differential equations

Indexed keywords

ARTICLE; DRUG DOSE REGIMEN; DRUG EFFECT; INTERMETHOD COMPARISON; LINEAR SYSTEM; MATHEMATICAL MODEL; NONLINEAR SYSTEM; PHARMACODYNAMICS; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SIMULATION; STATISTICAL ANALYSIS; STOCHASTIC MODEL; UNCERTAINTY;

ALGORITHMS; COMPUTER SIMULATION; INTESTINAL ABSORPTION; MODELS, STATISTICAL; PHARMACOKINETICS; SOFTWARE; STATISTICS, NONPARAMETRIC; STOCHASTIC PROCESSES;

EID: 27744515739     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-005-2105-9     Document Type: Article

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