Probiotics and prebiotics for the prevention of necrotizing enterocolitis

Current Infectious Disease Reports

Volumn 13, Issue 1, 2011, Pages 13-20

  Stenger, Michael R ^a   Reber, Kristina M ^a   Giannone, Peter J ^a   Nankervis, Craig A ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Bifidobacteria; Intestinal bacterial colonization; Lactobacillus; Necrotizing enterocolitis; Oligosaccharides; Prebiotics; Premature; Prevention; Probiotics

Indexed keywords

FRUCTOSE OLIGOSACCHARIDE; GALACTOSE OLIGOSACCHARIDE; GLUTATHIONE PEROXIDASE; PLACEBO; PREBIOTIC AGENT; PROBIOTIC AGENT; SUPEROXIDE DISMUTASE; SYNBIOTIC AGENT;

ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BIFIDOBACTERIUM ANIMALIS; BIFIDOBACTERIUM BIFIDUM; BIFIDOBACTERIUM BREVE; BIFIDOBACTERIUM LONGUM; BIFIDOBACTERIUM LONGUM INFANTIS; BOTTLE FEEDING; COMMENSAL; DIARRHEA; DIET SUPPLEMENTATION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ECZEMA; HUMAN; INTESTINE FLORA; IRRITABILITY; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS CASEI; LACTOBACILLUS RHAMNOSUS; MORBIDITY; MORTALITY; NECROTIZING ENTEROCOLITIS; NONHUMAN; PREMATURITY; RANDOMIZED CONTROLLED TRIAL (TOPIC); SIDE EFFECT; STREPTOCOCCUS THERMOPHILUS;

EID: 79551539840     PISSN: 15233847     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11908-010-0156-6     Document Type: Article

References (67)

1. MC Henry RL Moss 2009 Necrotizing enterocolitis Annu Rev Med 60 111 124 1:CAS:528:DC%2BD1MXitlynt7o%3D 10.1146/annurev.med.60.050207.092824 18817461
2. AM Thompson MJ Bizzarro 2008 Necrotizing enterocolitis in newborns: pathogenesis, prevention and management Drugs 68 1227 1238 1:CAS:528: DC%2BD1cXpslajsL0%3D 10.2165/00003495-200868090-00004 18547133 (Pubitemid 351822112)
3. KL Schnabl JE Van Aerde AB Thomson MT Clandinin 2008 Necrotizing enterocolitis: a multifactorial disease with no cure World J Gastroenterol 14 2142 2161 1:CAS:528:DC%2BD1cXnvVWmurk%3D 10.3748/wjg.14.2142 18407587
4. PW Lin TR Nasr BJ Stoll 2008 Necrotizing enterocolitis: recent scientific advances in pathophysiology and prevention Semin Perinatol 32 70 82 10.1053/j.semperi.2008.01.004 18346530 (Pubitemid 351381166)
5. CR Martin O Dammann EN Allred, et al. 2010 Neurodevelopment of extremely preterm infants who had necrotizing enterocolitis with or without late bacteremia J Pediatr 157 751 756 10.1016/j.jpeds.2010.05.042 20598317
6. TV Santulli JN Schullinger WC Heird, et al. 1975 Acute necrotizing enterocolitis in infancy: a review of 64 cases Pediatrics 55 376 387 1:STN:280:DyaE2M7psFKksA%3D%3D 1143976
7. J Neu M Douglas-Escobar M Lopez 2007 Microbes and the developing gastrointestinal tract Nutr Clin Pract 22 174 182 10.1177/0115426507022002174 17374791 This article provides a thorough review of the microbial colonization in the developing gastrointestinal tract
8. M Mshvildadze J Neu J Shuster, et al. 2010 Intestinal microbial ecology in premature infants assessed with non-culture-based techniques J Pediatr 156 20 25 10.1016/j.jpeds.2009.06.063 19783002
9. Hentges DJ: Human intestinal microflora in health and disease. 1983, New York: Academic Press.
10. MJ Morowitz V Poroyko M Caplan, et al. 2010 Redefining the role of intestinal microbes in the pathogenesis of necrotizing enterocolitis Pediatrics 125 777 785 10.1542/peds.2009-3149 20308210
11. G Biasucci M Rubini S Riboni, et al. 2010 Mode of delivery affects the bacterial community in the newborn gut Early Hum Dev 86 Suppl 1 13 15 10.1016/j.earlhumdev.2010.01.004 20133091
12. L Morelli 2008 Postnatal development of intestinal microflora as influenced by infant nutrition J Nutr 138 1791S 1795S 1:CAS:528: DC%2BD1cXhtVyksb%2FP 18716188
13. J Penders C Thijs C Vink, et al. 2006 Factors influencing the composition of the intestinal microbiota in early infancy Pediatrics 118 511 521 10.1542/peds.2005-2824 16882802 (Pubitemid 46085405)
14. CR Martin WA Walker 2008 Probiotics: role in pathophysiology and prevention in necrotizing enterocolitis Semin Perinatol 32 127 137 10.1053/j.semperi.2008.01.006 18346537 This article provides a complete review of gut defenses, bacterial colonization, and the use of probiotics for the prevention of NEC (Pubitemid 351381168)
15. S Salminen E Isolauri 2008 Opportunities for improving the health and nutrition of the human infant by probiotics Nestle Nutr Workshop Ser Pediatr Program 62 223 233 1:CAS:528:DC%2BD1MXhslWitr4%3D 10.1159/000146350 18626203 discussion 233-227
16. CN Emami M Petrosyan S Giuliani, et al. 2009 Role of the host defense system and intestinal microbial flora in the pathogenesis of necrotizing enterocolitis Surg Infect 10 407 417 10.1089/sur.2009.054
17. R Sharma JJ Tepas 3rd 2010 Microecology, intestinal epithelial barrier and necrotizing enterocolitis Pediatr Surg Int 26 11 21 10.1007/s00383-009-2536- 2 19967379
18. M Petrosyan YS Guner M Williams, et al. 2009 Current concepts regarding the pathogenesis of necrotizing enterocolitis Pediatr Surg Int 25 309 318 10.1007/s00383-009-2344-8 19301015
19. F Magne A Suau P Pochart JF Desjeux 2005 Fecal microbial community in preterm infants J Pediatr Gastroenterol Nutr 41 386 392 10.1097/01.mpg. 0000179855.38543.85 16205503 (Pubitemid 41407597)
20. RI Mackie A Sghir HR Gaskins 1999 Developmental microbial ecology of the neonatal gastrointestinal tract Am J Clin Nutr 69 1035S 1045S 1:CAS:528:DyaK1MXislGntbg%3D 10232646
21. PJ Giannone CA Nankervis JM Richter, et al. 2009 Prenatal lipopolysaccharide increases postnatal intestinal injury in a rat model of necrotizing enterocolitis J Pediatr Gastroenterol Nutr 48 276 282 1:CAS:528:DC%2BD1MXitlGgt7k%3D 10.1097/MPG.0b013e31818936b8 19274780
22. BW Kramer SG Kallapur TJ Moss, et al. 2010 Modulation of fetal inflammatory response on exposure to lipopolysaccharide by chorioamnion, lung, or gut in sheep Am J Obstet Gynecol 202 77 e71 79 10.1016/j.ajog.2009.07.058
23. TG Wolfs WA Buurman B Zoer, et al. 2009 Endotoxin induced chorioamnionitis prevents intestinal development during gestation in fetal sheep PLoS One 4 e5837 10.1371/journal.pone.0005837 19503810
24. N Aziz YW Cheng AB Caughey 2009 Neonatal outcomes in the setting of preterm premature rupture of membranes complicated by chorioamnionitis J Matern Fetal Neonatal Med 22 780 784 19557664
25. RL Goldenberg WW Andrews OM Faye-Petersen, et al. 2006 The Alabama preterm birth study: corticosteroids and neonatal outcomes in 23- to 32-week newborns with various markers of intrauterine infection Am J Obstet Gynecol 195 1020 1024 1:CAS:528:DC%2BD28XpvV2ksb8%3D 10.1016/j.ajog.2006.06.033 17000235 (Pubitemid 44419557)
26. H Kitajima Y Sumida R Tanaka, et al. 1997 Early administration of Bifidobacterium breve to preterm infants: randomised controlled trial Arch Dis Child Fetal Neonatal Ed 76 F101 F107 1:STN:280:DyaK2s3otV2rsg%3D%3D 10.1136/fn.76.2.F101 9135288
27. R Agarwal N Sharma R Chaudhry, et al. 2003 Effects of oral Lactobacillus GG on enteric microflora in low-birth-weight neonates J Pediatr Gastroenterol Nutr 36 397 402 10.1097/00005176-200303000-00019 12604982 (Pubitemid 39274616)
28. P Manzoni M Mostert ML Leonessa, et al. 2006 Oral supplementation with Lactobacillus casei subspecies rhamnosus prevents enteric colonization by Candida species in preterm neonates: a randomized study Clin Infect Dis 42 1735 1742 1:STN:280:DC%2BD283nsFCjtA%3D%3D 10.1086/504324 16705580 (Pubitemid 43839439)
29. R Mohan C Koebnick J Schildt, et al. 2006 Effects of Bifidobacterium lactis Bb12 supplementation on intestinal microbiota of preterm infants: a double-blind, placebo-controlled, randomized study J Clin Microbiol 44 4025 4031 10.1128/JCM.00767-06 16971641 (Pubitemid 44737246)
30. C Rouge H Piloquet MJ Butel, et al. 2009 Oral supplementation with probiotics in very-low-birth-weight preterm infants: a randomized, double-blind, placebo-controlled trial Am J Clin Nutr 89 1828 1835 1:CAS:528: DC%2BD1MXms1ejsbs%3D 10.3945/ajcn.2008.26919 19369375
31. EO Petrof K Kojima MJ Ropeleski, et al. 2004 Probiotics inhibit nuclear factor-kappaB and induce heat shock proteins in colonic epithelial cells through proteasome inhibition Gastroenterology 127 1474 1487 1:CAS:528: DC%2BD2cXhtVKisr3I 10.1053/j.gastro.2004.09.001 15521016 (Pubitemid 39457773)
32. EC Claud L Lu PM Anton, et al. 2004 Developmentally regulated IkappaB expression in intestinal epithelium and susceptibility to flagellin-induced inflammation Proc Natl Acad Sci U S A 101 7404 7408 1:CAS:528: DC%2BD2cXksFaksbs%3D 10.1073/pnas.0401710101 15123821 (Pubitemid 38638045)
33. R Korhonen R Korpela M Saxelin, et al. 2001 Induction of nitric oxide synthesis by probiotic Lactobacillus rhamnosus GG in J774 macrophages and human T84 intestinal epithelial cells Inflammation 25 223 232 1:CAS:528: DC%2BD3MXnsFWns7k%3D 10.1023/A:1010971703271 11580098 (Pubitemid 32846201)
34. JM Otte DK Podolsky 2004 Functional modulation of enterocytes by gram-positive and gram-negative microorganisms Am J Physiol Gastrointest Liver Physiol 286 G613 626 1:CAS:528:DC%2BD2cXjtlansrw%3D 10.1152/ajpgi.00341.2003 15010363
35. M Urao T Fujimoto GJ Lane, et al. 1999 Does probiotics administration decrease serum endotoxin levels in infants? J Pediatr Surg 34 273 276 1:STN:280:DyaK1M7mtVWlug%3D%3D 10.1016/S0022-3468(99)90189-6 10052803 (Pubitemid 29091431)
36. PW Lin LE Myers L Ray, et al. 2009 Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation Free Radic Biol Med 47 1205 1211 1:CAS:528:DC%2BD1MXhtFGqsbnP 10.1016/j.freeradbiomed. 2009.07.033 19660542
37. PW Lin TR Nasr AJ Berardinelli, et al. 2008 The probiotic Lactobacillus GG may augment intestinal host defense by regulating apoptosis and promoting cytoprotective responses in the developing murine gut Pediatr Res 64 511 516 10.1203/PDR.0b013e3181827c0f 18552706
38. A D'Souza L Fordjour A Ahmad, et al. 2010 Effects of probiotics, prebiotics, and synbiotics on messenger RNA expression of caveolin-1, NOS, and genes regulating oxidative stress in the terminal ileum of formula-fed neonatal rats Pediatr Res 67 526 531 20101198
39. CJ Hunter M Williams M Petrosyan, et al. 2009 Lactobacillus bulgaricus prevents intestinal epithelial cell injury caused by Enterobacter sakazakii-induced nitric oxide both in vitro and in the newborn rat model of necrotizing enterocolitis Infect Immun 77 1031 1043 1:CAS:528: DC%2BD1MXis1ais7k%3D 10.1128/IAI.01192-08 19075027
40. L Fordjour A D'Souza C Cai, et al. 2010 Comparative effects of probiotics, prebiotics, and synbiotics on growth factors in the large bowel in a rat model of formula-induced bowel inflammation J Pediatr Gastroenterol Nutr 51 507 513 10.1097/MPG.0b013e3181df5ff2 20683203
41. MS Caplan R Miller-Catchpole S Kaup, et al. 1999 Bifidobacterial supplementation reduces the incidence of necrotizing enterocolitis in a neonatal rat model Gastroenterology 117 577 583 1:STN:280:DyaK1MzpsV2qsA%3D%3D 10.1016/S0016-5085(99)70450-6 10464133 (Pubitemid 29409243)
42. MJ Butel N Roland A Hibert, et al. 1998 Clostridial pathogenicity in experimental necrotising enterocolitis in gnotobiotic quails and protective role of bifidobacteria J Med Microbiol 47 391 399 1:CAS:528:DyaK1cXjslSns70%3D 10.1099/00222615-47-5-391 9879939
43. RH Siggers J Siggers M Boye, et al. 2008 Early administration of probiotics alters bacterial colonization and limits diet-induced gut dysfunction and severity of necrotizing enterocolitis in preterm pigs J Nutr 138 1437 1444 1:CAS:528:DC%2BD1cXovFWns7k%3D 18641188
44. L Khailova K Dvorak KM Arganbright, et al. 2009 Bifidobacterium bifidum improves intestinal integrity in a rat model of necrotizing enterocolitis Am J Physiol Gastrointest Liver Physiol 297 G940 949 1:CAS:528:DC%2BD1MXhsVahtrzP 10.1152/ajpgi.00141.2009 20501441
45. Khailova L, Mount Patrick SK, Arganbright KM, et al.: Bifidobacterium bifidum reduces apoptosis in the intestinal epithelium in necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol 2010, 299:G1118-1127.
46. AB Hoyos 1999 Reduced incidence of necrotizing enterocolitis associated with enteral administration of Lactobacillus acidophilus and Bifidobacterium infantis to neonates in an intensive care unit Int J Infect Dis 3 197 202 1:STN:280:DC%2BD3c%2FksFWhtA%3D%3D 10.1016/S1201-9712(99)90024-3 10575148
47. HC Lin BH Su AC Chen, et al. 2005 Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants Pediatrics 115 1 4 10.1542/peds.2005-0245 15629973 (Pubitemid 43843263)
48. A Bin-Nun R Bromiker M Wilschanski, et al. 2005 Oral probiotics prevent necrotizing enterocolitis in very low birth weight neonates J Pediatr 147 192 196 10.1016/j.jpeds.2005.03.054 16126048 (Pubitemid 41207832)
49. LQ Li B Wu XX Gao, et al. 2006 Role of probiotics in the prevention of neonatal necrotizing enterocolitis: A case-control study Zhongguo Dang Dai Er Ke Za Zhi 8 464 466 17178035
50. H Awad H Mokhtar SS Imam, et al. 2010 Comparison between killed and living probiotic usage versus placebo for the prevention of necrotizing enterocolitis and sepsis in neonates Pak J Biol Sci 13 253 262 1:STN:280:DC%2BC3czmvF2rsA%3D%3D 10.3923/pjbs.2010.253.262 20506712
51. Braga TD, da Silva GA, de Lira PI, de Carvalho Lima M. Efficacy of Bifidobacterium breve and Lactobacillus casei oral supplementation on necrotizing enterocolitis in very-low-birth-weight preterm infants: a double-blind, randomized, controlled trial. Am J Clin Nutr 2010 epub Oct 27.
52. C Dani R Biadaioli G Bertini, et al. 2002 Probiotics feeding in prevention of urinary tract infection, bacterial sepsis and necrotizing enterocolitis in preterm infants. A prospective double-blind study Biol Neonate 82 103 108 1:CAS:528:DC%2BD38XlvFOiu78%3D 10.1159/000063096 12169832
53. R Luoto J Matomaki E Isolauri L Lehtonen 2010 Incidence of necrotizing enterocolitis in very-low-birth-weight infants related to the use of Lactobacillus GG Acta Paediatr 99 1135 1138 1:STN:280:DC%2BC3cnnslelsA%3D%3D 10.1111/j.1651-2227.2010.01795.x 20219023
54. G Deshpande S Rao S Patole M Bulsara 2010 Updated meta-analysis of probiotics for preventing necrotizing enterocolitis in preterm neonates Pediatrics 125 921 930 10.1542/peds.2009-1301 20403939 This recent meta-analysis for probiotics to prevent NEC includes 11 trials involving 2176 infants
55. IC Chou HT Kuo JS Chang, et al. 2010 Lack of effects of oral probiotics on growth and neurodevelopmental outcomes in preterm very low birth weight infants J Pediatr 156 393 396 10.1016/j.jpeds.2009.09.051 19914635
56. GR Gibson MB Roberfroid 1995 Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics J Nutr 125 1401 1412 1:CAS:528:DyaK2MXmt1ajsrY%3D 7782892
57. M Roberfroid GR Gibson L Hoyles, et al. 2010 Prebiotic effects: metabolic and health benefits Br J Nutr 104 S1 S63 1:CAS:528:DC%2BC3cXht1GjsLfK 10.1017/S0007114510003363 20920376
58. MJ Gnoth C Kunz E Kinne-Saffran S Rudloff 2000 Human milk oligosaccharides are minimally digested in vitro J Nutr 130 3014 3020 1:CAS:528:DC%2BD3cXptVKmur0%3D 11110861
59. MJ Butel AJ Waligora-Dupriet O Szylit 2002 Oligofructose and experimental model of neonatal necrotising enterocolitis Br J Nutr 87 Suppl 2 S213 S219 1:CAS:528:DC%2BD38XkvVCisLs%3D 10.1079/BJN/2002540 12088521
60. S Rao R Srinivasjois S Patole 2009 Prebiotic supplementation in full-term neonates: a systematic review of randomized controlled trials Arch Pediatr Adolesc Med 163 755 764 10.1001/archpediatrics.2009.94 19652109
61. G Moro S Arslanoglu B Stahl, et al. 2006 A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age Arch Dis Child 91 814 819 1:STN:280:DC%2BD28rmsVaktQ%3D%3D 10.1136/adc.2006.098251 16873437 (Pubitemid 44521163)
62. R Srinivasjois S Rao S Patole 2009 Prebiotic supplementation of formula in preterm neonates: a systematic review and meta-analysis of randomised controlled trials Clin Nutr 28 237 242 1:CAS:528:DC%2BD1MXntVKgtL8%3D 10.1016/j.clnu.2009.03.008 19359074
63. A Kapiki C Costalos C Oikonomidou, et al. 2007 The effect of a fructo-oligosaccharide supplemented formula on gut flora of preterm infants Early Hum Dev 83 335 339 1:CAS:528:DC%2BD2sXkt1arurs%3D 10.1016/j.earlhumdev. 2006.07.003 16978805 (Pubitemid 46561170)
64. J Schrezenmeir M de Vrese 2001 Probiotics, prebiotics, and synbiotics-approaching a definition Am J Clin Nutr 73 361S 364S 1:CAS:528:DC%2BD3MXpvF2isA%3D%3D 11157342
65. MA Underwood NH Salzman SH Bennett, et al. 2009 A randomized placebo-controlled comparison of 2 prebiotic/probiotic combinations in preterm infants: impact on weight gain, intestinal microbiota, and fecal short-chain fatty acids J Pediatr Gastroenterol Nutr 48 216 225 10.1097/MPG.0b013e31818de195 19179885
66. RF Soll 2010 Probiotics: are we ready for routine use? Pediatrics 125 1071 1072 10.1542/peds.2010-0643 20421256
67. HR Christensen H Frokiaer JJ Pestka 2002 Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells J Immunol 168 171 178 1:CAS:528:DC%2BD38Xht1Gntw%3D%3D 11751960