Cardiac magnetic resonance in hypertrophic cardiomyopathy

Current Cardiology Reports

Volumn 13, Issue 1, 2011, Pages 67-76

  Desai, Milind Y ^a   Dhillon, Ashwat ^a   To, Andrew C Y ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Cardiac magnetic resonance; Hypertrophic cardiomyopathy

Indexed keywords

ARTICLE; CARDIAC IMAGING; CARDIOVASCULAR RISK; DIAGNOSTIC ACCURACY; DIFFERENTIAL DIAGNOSIS; FUNCTIONAL ASSESSMENT; GENETIC SCREENING; HEALTH CARE QUALITY; HEALTH CARE UTILIZATION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE OUTFLOW TRACT OBSTRUCTION; HEART LEFT VENTRICLE WALL; HEART MUSCLE FIBROSIS; HEART MUSCLE ISCHEMIA; HEART PAPILLARY MUSCLE; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; IMAGE ANALYSIS; IMAGE DISPLAY; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENOTYPE; PROGNOSIS; RISK ASSESSMENT; TREATMENT PLANNING;

ADULT; AGED; CARDIOMYOPATHY, HYPERTROPHIC; DIAGNOSIS, DIFFERENTIAL; DISEASE PROGRESSION; FIBROSIS; HEMODYNAMICS; HUMANS; MAGNETIC RESONANCE IMAGING, CINE; MALE; MYOCARDIAL ISCHEMIA; PAPILLARY MUSCLES; PHENOTYPE; RISK FACTORS; TREATMENT OUTCOME;

EID: 79551520246     PISSN: 15233782     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11886-010-0149-y     Document Type: Article

References (74)

1. BJ Maron 2002 Hypertrophic cardiomyopathy: a systematic review JAMA 287 1308 1320 10.1001/jama.287.10.1308 11886323
2. P Spirito F Chiarella L Carratino, et al. 1989 Clinical course and prognosis of hypertrophic cardiomyopathy in an outpatient population N Engl J Med 320 749 755 1:STN:280:DyaL1M7lvFehsg%3D%3D 10.1056/NEJM198903233201201 2646539
3. P Elliott 2001 Relation between the severity of left ventricular hypertrophy and prognosis in patients with hypertrophic cardiomyopathy Lancet 357 420 424 1:STN:280:DC%2BD3M7nt12itg%3D%3D 10.1016/S0140-6736(00)04005-8 11273061 (Pubitemid 32156140)
4. BJ Maron WJ McKenna GK Danielson, et al. 2003 American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines J Am Coll Cardiol 42 1687 1713 10.1016/S0735-1097(03)00941-0 14607462 (Pubitemid 37383745)
5. P Richard P Charron L Carrier, et al. 2003 Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy Circulation 107 2227 2232 10.1161/01.CIR. 0000066323.15244.54 12707239 (Pubitemid 36547217)
6. BJ Maron 1997 Hypertrophic cardiomyopathy Lancet 350 127 133 1:STN:280:DyaK2sznt12hsw%3D%3D 10.1016/S0140-6736(97)01282-8 9228976 (Pubitemid 27313649)
7. P Spirito 1997 The management of hypertrophic cardiomyopathy N Engl J Med 336 775 785 1:STN:280:DyaK2s3gtFeksA%3D%3D 10.1056/NEJM199703133361107 9052657 (Pubitemid 27113973)
8. P Elliott WJ McKenna 2004 Hypertrophic cardiomyopathy Lancet 363 1881 1891 1:CAS:528:DC%2BD2cXks1ert7o%3D 10.1016/S0140-6736(04)16358-7 15183628 (Pubitemid 38748646)
9. PM Elliott J Poloniecki S Dickie, et al. 2000 Sudden death in hypertrophic cardiomyopathy: identification of high risk patients J Am Coll Cardiol 36 2212 2218 1:STN:280:DC%2BD3M%2FnslaqsA%3D%3D 10.1016/S0735-1097(00) 01003-2 11127463
10. P Spirito P Bellone KM Harris, et al. 2000 Magnitude of left ventricular hypertrophy and risk of sudden death in hypertrophic cardiomyopathy N Engl J Med 342 1778 1785 1:STN:280:DC%2BD3c3psVOqsw%3D%3D 10.1056/NEJM200006153422403 10853000 (Pubitemid 30390237)
11. L Monserrat PM Elliott JR Gimeno, et al. 2003 Non-sustained ventricular tachycardia in hypertrophic cardiomyopathy: an independent marker of sudden death risk in young patients J Am Coll Cardiol 42 873 879 10.1016/S0735-1097(03) 00827-1 12957435 (Pubitemid 37059747)
12. N Yoshida H Ikeda T Wada, et al. 1998 Exercise-induced abnormal blood pressure responses are related to subendocardial ischemia in hypertrophic cardiomyopathy J Am Coll Cardiol 32 1938 1942 1:STN:280:DyaK1M%2FntlGrtA%3D%3D 10.1016/S0735-1097(98)00498-7 9857875 (Pubitemid 29010458)
13. H Watkins 2000 Sudden death in hypertrophic cardiomyopathy N Engl J Med 342 422 424 1:STN:280:DC%2BD3c7hs12muw%3D%3D 10.1056/NEJM200002103420609 10666434 (Pubitemid 30084542)
14. MS Maron I Olivotto S Betocchi, et al. 2003 Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy N Engl J Med 348 295 303 10.1056/NEJMoa021332 12540642 (Pubitemid 36119984)
15. MJ Kofflard FJ Ten Cate C van der Lee RT van Domburg 2003 Hypertrophic cardiomyopathy in a large community-based population: clinical outcome and identification of risk factors for sudden cardiac death and clinical deterioration J Am Coll Cardiol 41 987 993 10.1016/S0735-1097(02)03004-8 12651046 (Pubitemid 36315542)
16. K Teraoka M Hirano H Ookubo, et al. 2004 Delayed contrast enhancement of MRI in hypertrophic cardiomyopathy Magn Reson Imaging 22 155 161 10.1016/j.mri.2003.08.009 15010107 (Pubitemid 38326634)
17. DH Kwon RM Setser ZB Popovic, et al. 2008 Association of myocardial fibrosis, electrocardiography and ventricular tachyarrhythmia in hypertrophic cardiomyopathy: a delayed contrast enhanced MRI study Int J Cardiovasc Imaging 24 617 625 10.1007/s10554-008-9292-6 18204915
18. AS Adabag BJ Maron E Appelbaum, et al. 2008 Occurrence and frequency of arrhythmias in hypertrophic cardiomyopathy in relation to delayed enhancement on cardiovascular magnetic resonance J Am Coll Cardiol 51 1369 1374 10.1016/j.jacc.2007.11.071 18387438 (Pubitemid 351443083)
19. R Rubinshtein JF Glockner SR Ommen, et al. 2010 Characteristics and clinical significance of late gadolinium enhancement by contrast-enhanced magnetic resonance imaging in patients with hypertrophic cardiomyopathy Circ Heart Fail 3 51 58 10.1161/CIRCHEARTFAILURE.109.854026 19850699 This article discusses the prognostic utility of LGE in the HCM population
20. R O'Hanlon A Grasso M Roughton, et al. 2010 Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy J Am Coll Cardiol 56 867 874 10.1016/j.jacc.2010.05.010 20688032 This article discusses the prognostic utility of LGE in the HCM population
21. O Bruder A Wagner CJ Jensen, et al. 2010 Myocardial scar visualized by cardiovascular magnetic resonance imaging predicts major adverse events in patients with hypertrophic cardiomyopathy J Am Coll Cardiol 56 875 887 10.1016/j.jacc.2010.05.007 20667520
22. JA Lima MY Desai 2004 Cardiovascular magnetic resonance imaging: current and emerging applications J Am Coll Cardiol 44 1164 1171 10.1016/j.jacc.2004.06. 033 15364314 (Pubitemid 39208868)
23. OP Simonetti RJ Kim DS Fieno, et al. 2001 An improved MR imaging technique for the visualization of myocardial infarction Radiology 218 215 223 1:STN:280:DC%2BD3MzitFCntg%3D%3D 11152805
24. MS Maron BJ Maron C Harrigan, et al. 2009 Hypertrophic cardiomyopathy phenotype revisited after 50 years with cardiovascular magnetic resonance J Am Coll Cardiol 54 220 228 10.1016/j.jacc.2009.05.006 19589434
25. C Rickers NM Wilke M Jerosch-Herold, et al. 2005 Utility of cardiac magnetic resonance imaging in the diagnosis of hypertrophic cardiomyopathy Circulation 112 855 861 10.1161/CIRCULATIONAHA.104.507723 16087809 (Pubitemid 41170072)
26. JC Moon NG Fisher WJ McKenna DJ Pennell 2004 Detection of apical hypertrophic cardiomyopathy by cardiovascular magnetic resonance in patients with non-diagnostic echocardiography Heart 90 645 649 1:STN:280: DC%2BD2c3kslSisg%3D%3D 10.1136/hrt.2003.014969 15145868
27. MS Maron 2009 The current and emerging role of cardiovascular magnetic resonance imaging in hypertrophic cardiomyopathy J Cardiovasc Transl Res 2 415 425 10.1007/s12265-009-9136-3 20560000
28. I Olivotto MS Maron C Autore, et al. 2008 Assessment and significance of left ventricular mass by cardiovascular magnetic resonance in hypertrophic cardiomyopathy J Am Coll Cardiol 52 559 566 10.1016/j.jacc.2008.04.047 18687251
29. J Schulz-Menger H Abdel-Aty A Rudolph, et al. 2008 Gender-specific differences in left ventricular remodelling and fibrosis in hypertrophic cardiomyopathy: insights from cardiovascular magnetic resonance Eur J Heart Fail 10 850 854 10.1016/j.ejheart.2008.06.021 18692438
30. MS Maron JJ Finley JM Bos, et al. 2008 Prevalence, clinical significance, and natural history of left ventricular apical aneurysms in hypertrophic cardiomyopathy Circulation 118 1541 1549 10.1161/CIRCULATIONAHA.108.781401 18809796
31. MS Maron TH Hauser E Dubrow, et al. 2007 Right ventricular involvement in hypertrophic cardiomyopathy Am J Cardiol 100 1293 1298 10.1016/j.amjcard.2007. 05.061 17920373 (Pubitemid 47500158)
32. DH Kwon RM Setser M Thamilarasan, et al. 2008 Abnormal papillary muscle morphology is independently associated with increased left ventricular outflow tract obstruction in hypertrophic cardiomyopathy Heart 94 1295 1301 1:STN:280:DC%2BD1cnhtFegsg%3D%3D 10.1136/hrt.2007.118018 17690158
33. CJ Harrigan E Appelbaum BJ Maron, et al. 2008 Significance of papillary muscle abnormalities identified by cardiovascular magnetic resonance in hypertrophic cardiomyopathy Am J Cardiol 101 668 673 10.1016/j.amjcard.2007.10. 032 18308018 (Pubitemid 351635561)
34. O'Connor M, Wolstenholme GE, eds: Hypertrophic Obstructive Cardiomyopathy. London: Churchill; 1971.
35. HG Klues BJ Maron AL Dollar WC Roberts 1992 Diversity of structural mitral valve alterations in hypertrophic cardiomyopathy Circulation 85 1651 1660 1:STN:280:DyaK383ktVOnug%3D%3D 1572023
36. HG Klues WC Roberts BJ Maron 1993 Morphological determinants of echocardiographic patterns of mitral valve systolic anterior motion in obstructive hypertrophic cardiomyopathy Circulation 87 1570 1579 1:STN:280:DyaK3s3lvVyqtw%3D%3D 8491013
37. MV Sherrid DZ Gunsburg S Moldenhauer G Pearle 2000 Systolic anterior motion begins at low left ventricular outflow tract velocity in obstructive hypertrophic cardiomyopathy J Am Coll Cardiol 36 1344 1354 1:STN:280: DC%2BD3cvnslWhsQ%3D%3D 10.1016/S0735-1097(00)00830-5 11028493
38. RL Reis MR Bolton JF King, et al. 1974 Anterion-superior displacement of papillary muscles producing obstruction and mitral regurgitation in idiopathic hypertrophic subaortic stenosis. Operative relief by posterior-superior realignment of papillary muscles following ventricular septal myectomy Circulation 50 II181 II188 1:STN:280:DyaE2c3nvVChtg%3D%3D 4276504
39. MW Kon ED Grech SY Ho, et al. 1997 Anomalous papillary muscle as a cause of left ventricular outflow tract obstruction in an adult Ann Thorac Surg 63 232 234 1:STN:280:DyaK2s7ks1Chsg%3D%3D 10.1016/S0003-4975(96)01085-5 8993276 (Pubitemid 27039073)
40. HG Klues WC Roberts BJ Maron 1991 Anomalous insertion of papillary muscle directly into anterior mitral leaflet in hypertrophic cardiomyopathy. Significance in producing left ventricular outflow obstruction Circulation 84 1188 1197 1:STN:280:DyaK3Mzls1KgtA%3D%3D 1884449
41. WA Schiavone DM Cosgrove HM Lever, et al. 1988 Long-term follow-up of patients with left ventricular outflow tract obstruction after Carpentier ring mitral valvuloplasty Circulation 78 I60 I65 1:STN:280:DyaL1czhtFCrsQ%3D%3D 3409519
42. BJ Maron SE Epstein RO Bonow, et al. 1984 Obstructive hypertrophic cardiomyopathy associated with minimal left ventricular hypertrophy Am J Cardiol 53 377 379 1:STN:280:DyaL2c7isFSitA%3D%3D 10.1016/0002-9149(84)90479-X 6229997
43. BA Austin DH Kwon NG Smedira, et al. 2009 Abnormally thickened papillary muscle resulting in dynamic left ventricular outflow tract obstruction: an unusual presentation of hypertrophic cardiomyopathy J Am Soc Echocardiogr 22 105.e5 e6 10.1016/j.echo.2008.10.022
44. R Bryant 3rd 2008 Smedira NG: Papillary muscle realignment for symptomatic left ventricular outflow tract obstruction J Thorac Cardiovasc Surg 135 223 224 10.1016/j.jtcvs.2007.08.034 18179954
45. SJ Dong JH MacGregor AP Crawley, et al. 1994 Left ventricular wall thickness and regional systolic function in patients with hypertrophic cardiomyopathy. A three-dimensional tagged magnetic resonance imaging study Circulation 90 1200 1209 1:STN:280:DyaK2czntl2htQ%3D%3D 8087929
46. CM Kramer N Reichek VA Ferrari, et al. 1994 Regional heterogeneity of function in hypertrophic cardiomyopathy Circulation 90 186 194 1:STN:280:DyaK2c3pvVWmsg%3D%3D 8025995
47. P Sipola K Lauerma P Jaaskelainen, et al. 2005 Cine MR imaging of myocardial contractile impairment in patients with hypertrophic cardiomyopathy attributable to Asp175Asn mutation in the alpha-tropomyosin gene Radiology 236 815 824 10.1148/radiol.2363041165 16014439 (Pubitemid 41170842)
48. SE Petersen M Jerosch-Herold LE Hudsmith, et al. 2007 Evidence for microvascular dysfunction in hypertrophic cardiomyopathy: new insights from multiparametric magnetic resonance imaging Circulation 115 2418 2425 10.1161/CIRCULATIONAHA.106.657023 17452610 (Pubitemid 46717964)
49. RJ Kim DS Fieno TB Parrish, et al. 1999 Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function Circulation 100 1992 2002 1:STN:280:DC%2BD3c%2FivVensg%3D%3D 10556226
50. H Mahrholdt A Wagner TA Holly, et al. 2002 Reproducibility of chronic infarct size measurement by contrast-enhanced magnetic resonance imaging Circulation 106 2322 2327 1:CAS:528:DC%2BD38XotV2iu7k%3D 10.1161/01.CIR. 0000036368.63317.1C 12403661 (Pubitemid 35244732)
51. JC Moon M Sheppard E Reed, et al. 2006 The histological basis of late gadolinium enhancement cardiovascular magnetic resonance in a patient with Anderson-Fabry disease J Cardiovasc Magn Reson 8 479 482 10.1080/ 10976640600605002 16755835
52. DH Kwon NG Smedira ER Rodriguez, et al. 2009 Cardiac magnetic resonance detection of myocardial scarring in hypertrophic cardiomyopathy: correlation with histopathology and prevalence of ventricular tachycardia J Am Coll Cardiol 54 242 249 10.1016/j.jacc.2009.04.026 19589437
53. BJ Maron JK Wolfson SE Epstein WC Roberts 1986 Intramural ("small vessel") coronary artery disease in hypertrophic cardiomyopathy J Am Coll Cardiol 8 545 557 1:STN:280:DyaL28zgsFChtA%3D%3D 10.1016/S0735-1097(86)80181-4 3745699
54. J Shirani R Pick WC Roberts BJ Maron 2000 Morphology and significance of the left ventricular collagen network in young patients with hypertrophic cardiomyopathy and sudden cardiac death J Am Coll Cardiol 35 36 44 1:STN:280:DC%2BD3c7gtVaisw%3D%3D 10.1016/S0735-1097(99)00492-1 10636256 (Pubitemid 30061256)
55. M Kitamura M Shimizu H Ino, et al. 2001 Collagen remodeling and cardiac dysfunction in patients with hypertrophic cardiomyopathy: the significance of type III and VI collagens Clin Cardiol 24 325 329 1:STN:280: DC%2BD3MvjsFWhtA%3D%3D 10.1002/clc.4960240413 11303702
56. L Choudhury H Mahrholdt A Wagner, et al. 2002 Myocardial scarring in asymptomatic or mildly symptomatic patients with hypertrophic cardiomyopathy J Am Coll Cardiol 40 2156 2164 10.1016/S0735-1097(02)02602-5 12505229 (Pubitemid 36005903)
57. JC Moon J Mogensen PM Elliott, et al. 2005 Myocardial late gadolinium enhancement cardiovascular magnetic resonance in hypertrophic cardiomyopathy caused by mutations in troponin I Heart 91 1036 1040 1:CAS:528: DC%2BD2MXps1Cku7c%3D 10.1136/hrt.2004.041384 16020591 (Pubitemid 41060010)
58. JC Moon WJ McKenna JA McCrohon, et al. 2003 Toward clinical risk assessment in hypertrophic cardiomyopathy with gadolinium cardiovascular magnetic resonance J Am Coll Cardiol 41 1561 1567 10.1016/S0735-1097(03)00189-X 12742298 (Pubitemid 36543376)
59. MS Maron E Appelbaum CJ Harrigan, et al. 2008 Clinical profile and significance of delayed enhancement in hypertrophic cardiomyopathy Circ Heart Fail 1 184 191 10.1161/CIRCHEARTFAILURE.108.768119 19808288
60. ZB Popovic DH Kwon M Mishra, et al. 2008 Association between regional ventricular function and myocardial fibrosis in hypertrophic cardiomyopathy assessed by speckle tracking echocardiography and delayed hyperenhancement magnetic resonance imaging J Am Soc Echocardiogr 21 1299 1305 10.1016/j.echo.2008.09.011 19041572
61. J Schulz-Menger H Abdel-Aty A Busjahn, et al. 2006 Left ventricular outflow tract planimetry by cardiovascular magnetic resonance differentiates obstructive from non-obstructive hypertrophic cardiomyopathy J Cardiovasc Magn Reson 8 741 746 10.1080/10976640600737383 16891234 (Pubitemid 44195996)
62. P Chai R Mohiaddin 2005 How we perform cardiovascular magnetic resonance flow assessment using phase-contrast velocity mapping J Cardiovasc Magn Reson 7 705 716 16136862
63. DH Kwon NG Smedira ZB Popovic, et al. 2009 Steep left ventricle to aortic root angle and hypertrophic obstructive cardiomyopathy: study of a novel association using 3-dimensional multi-modality imaging Heart 95 1784 1791 1:STN:280:DC%2BD1MnptVSlsQ%3D%3D 10.1136/hrt.2009.166777 19549621
64. T Boonyasirinant P Rajiah RM Setser, et al. 2009 Aortic stiffness is increased in hypertrophic cardiomyopathy with myocardial fibrosis: novel insights in vascular function from magnetic resonance imaging J Am Coll Cardiol 54 255 262 10.1016/j.jacc.2009.03.060 19589439 This article sheds newer insights into the pathophysiology of HCM, including abnormal ventricular vascular interactions
65. Austin BA, Popovic ZB, Kwon DH, et al.: Aortic stiffness independently predicts exercise capacity in hypertrophic cardiomyopathy: a multimodality imaging study. Heart 2010, 96(16):1303-1310.
66. Kwon DH, Smedira NG, Thamilarasan M, et al.: Characteristics and surgical outcomes of symptomatic patients with hypertrophic cardiomyopathy with abnormal papillary muscle morphology undergoing papillary muscle reorientation. J Thorac Cardiovasc Surg 2010, 140(2):317-324.
67. J Schulz-Menger O Strohm J Waigand, et al. 2000 The value of magnetic resonance imaging of the left ventricular outflow tract in patients with hypertrophic obstructive cardiomyopathy after septal artery embolization Circulation 101 1764 1766 1:STN:280:DC%2BD3c3jtlyjsQ%3D%3D 10769274
68. US Valeti RA Nishimura DR Holmes, et al. 2007 Comparison of surgical septal myectomy and alcohol septal ablation with cardiac magnetic resonance imaging in patients with hypertrophic obstructive cardiomyopathy J Am Coll Cardiol 49 350 357 10.1016/j.jacc.2006.08.055 17239717 (Pubitemid 46097376)
69. SF Nagueh LL Bachinski D Meyer, et al. 2001 Tissue Doppler imaging consistently detects myocardial abnormalities in patients with hypertrophic cardiomyopathy and provides a novel means for an early diagnosis before and independently of hypertrophy Circulation 104 128 130 1:STN:280: DC%2BD3Mzpt1Kqsg%3D%3D 11447072
70. CY Ho NK Sweitzer B McDonough, et al. 2002 Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy Circulation 105 2992 2997 10.1161/01.CIR.0000019070. 70491.6D 12081993 (Pubitemid 34693832)
71. SF Nagueh J McFalls D Meyer, et al. 2003 Tissue Doppler imaging predicts the development of hypertrophic cardiomyopathy in subjects with subclinical disease Circulation 108 395 398 10.1161/01.CIR.0000084500.72232.8D 12860897 (Pubitemid 36935530)
72. T Germans AA Wilde CJ van Echteld, et al. 2007 Structural abnormalities of the left ventricle in hypertrophic cardiomyopathy mutation carriers detectable before the development of hypertrophy Neth Heart J 15 161 163 1:STN:280:DC%2BD1cvjsVymsg%3D%3D 10.1007/BF03085974 18604279
73. CY Ho B Lopez OR Coelho-Filho, et al. 2010 Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy N Engl J Med 363 552 563 1:CAS:528:DC%2BC3cXpvVSjtL8%3D 10.1056/NEJMoa1002659 20818890
74. AM Maceira J Joshi SK Prasad, et al. 2005 Cardiovascular magnetic resonance in cardiac amyloidosis Circulation 111 186 193 10.1161/01.CIR. 0000152819.97857.9D 15630027 (Pubitemid 40139730)