C-reactive protein overexpression exacerbates pressure overload-induced cardiac remodeling through enhanced inflammatory response

Hypertension

Volumn 57, Issue 2, 2011, Pages 208-215

  Nagai, Toshiyuki ^a   Anzai, Toshihisa ^a   Kaneko, Hidehiro ^a   Mano, Yoshinori ^a   Anzai, Atsushi ^a   Maekawa, Yuichiro ^a   Takahashi, Toshiyuki ^a   Meguro, Tomomi ^a   Yoshikawa, Tsutomu ^a   Fukuda, Keiichi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

C reactive protein; cardiac remodeling; inflammation; macrophage; NF B p65; pressure overload

Indexed keywords

ANGIOTENSIN RECEPTOR; ANGIOTENSIN RECEPTOR 1; ATRIAL NATRIURETIC FACTOR; C REACTIVE PROTEIN; CD68 ANTIGEN; COLLAGEN TYPE 1; GLUTATHIONE PEROXIDASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SYNAPTOTAGMIN I; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; BINDING AFFINITY; CONTROLLED STUDY; DISEASE COURSE; DISEASE EXACERBATION; DNA BINDING; GENE OVEREXPRESSION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; HEART WEIGHT; HYPOTHESIS; INFLAMMATION; LUNG WEIGHT; MACROPHAGE; MALE; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; SHAM PROCEDURE; TRANSGENIC MOUSE;

ANIMALS; AORTA; C-REACTIVE PROTEIN; CONSTRICTION, PATHOLOGIC; FIBROSIS; GENE EXPRESSION; GLUTATHIONE PEROXIDASE; HEART; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCARDIUM; NADPH OXIDASE; ORGAN SIZE; PRESSURE; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA; VENTRICULAR REMODELING;

EID: 79551502515     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.110.158915     Document Type: Review

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