Synthesis, anticancer activity, and iron affinity of the Actinoplanes metabolite 7,8-dihydroxy-1-methylnaphtho[2,3-c]furan-4,9-dione

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 3, 2011, Pages 1264-1267

  Breyer, Sandra ^a   Effenberger Neidnicht, Katharina ^a   Knauer, Sebastian ^a   Schobert, Rainer ^a  

^a UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

Anticancer activity; Isofuranonaphthoquinone; Ortho lithiation; Siderophore

Indexed keywords

3 FORMYL 4 (2,3 DIMETHOXYBENZOYL) 5 METHYLFURAN; 4 (2,3 DIMETHOXYBENZOYL) 5 METHYLFURAN 3 CARBOXYLIC ACID; 4 HYDROXYMETHYL 2 METHYL 3 (2,3 DIMETHOXYBENZOYL)FURAN; 7,8 DIHYDROXY 1 METHYLNAPHTHO[2,3 C]FURAN 4,9 DIONE; 8 HYDROXY 7 METHOXY 1 METHYLNAPHTHO[2,3 C]FURAN 4,9 DIONE; ANTINEOPLASTIC AGENT; IRON; LACTONE; QUINONE DERIVATIVE; SIDEROPHORE; UNCLASSIFIED DRUG;

ACYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM; BINDING AFFINITY; BREAST CANCER; CANCER INHIBITION; COLON CARCINOMA; CONTROLLED STUDY; DEMETHYLATION; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IRON BINDING CAPACITY; LEUKEMIA CELL; MELANOMA CELL; OXIDATION; RING OPENING; UTERINE CERVIX CARCINOMA;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; FIBROBLASTS; FURANS; HUMANS; IRON; MICROMONOSPORACEAE; MOLECULAR STRUCTURE; NAPHTHOQUINONES; ORGANOMETALLIC COMPOUNDS;

ACTINOPLANES;

EID: 79551501114     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.12.012     Document Type: Article

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