Advantage of high-resolution melting curve analysis over conformation-sensitive gel electrophoresis for mutational screening of BRCA1 and BRCA2 genes

Clinica Chimica Acta

Volumn 412, Issue 7-8, 2011, Pages 578-582

  de Juan Jiménez, Inmaculada ^a   Cardeñosa, Eva Esteban ^a   Suela, Sarai Palanca ^a   González, Eva Barragán ^a   Trejo, Dolores Salas ^b   Lluch, Oscar Fuster ^a   Gilabert, Pascual Bolufer ^a  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

^b Dirección General de Salud Pública   (Spain)

Author keywords

BRCA1; BRCA2; Conformation sensitive gel electrophoresis (CSGE); Hereditary breast and ovarian cancer; High resolution melting analysis (HRMA); Mutation screening methods

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DNA;

ANALYTIC METHOD; ARTICLE; BRCA2 GENE; CONFORMATION SENSITIVE GEL ELECTROPHORESIS; CONTROLLED STUDY; EXON; GEL ELECTROPHORESIS; GENE MUTATION; GENE SEQUENCE; GENETIC SCREENING; GENETIC VARIABILITY; HIGH RESOLUTION MELTING CURVE ANALYSIS; HIGH RISK POPULATION; HUMAN; INTERMETHOD COMPARISON; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; RELIABILITY; SENSITIVITY AND SPECIFICITY;

BASE SEQUENCE; DNA PROBES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENES, BRCA1; GENES, BRCA2; GENETIC TESTING; HUMANS; MUTATION; POLYMERASE CHAIN REACTION;

EID: 79551499986     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2010.12.007     Document Type: Article

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