Executive function and short-term remission of geriatric depression: The role of semantic strategy

American Journal of Geriatric Psychiatry

Volumn 19, Issue 2, 2011, Pages 115-122

  Morimoto, Sarah Shizuko ^a   Gunning, Faith M ^a   Murphy, Christopher F ^a   Kanellopoulos, Dora ^a   Kelly, Robert E ^a   Alexopoulos, George S ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

depression; Executive function; geriatric; Mattis Dementia Rating Scale; remission; semantic strategy

Indexed keywords

ESCITALOPRAM;

AGED; ARTICLE; COGNITION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EXECUTIVE FUNCTION; FEMALE; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MATTIS DEMENTIA RATING SCALE; PROPORTIONAL HAZARDS MODEL; RATING SCALE; REMISSION; VERBAL MEMORY;

EID: 79551493683     PISSN: 10647481     EISSN: 15457214     Source Type: Journal    
DOI: 10.1097/JGP.0b013e3181e751c4     Document Type: Article

References (33)

1. Alexopoulos GS, Kiosses DN, Klimstra S, et al: Clinical presentation of the "depression-executive dysfunction syndrome" of late life. Am J Geriatr Psychiatry 2002; 10:98-106
2. Alexopoulos GS, Kiosses DN, Murphy C, et al: Executive dysfunction, heart disease burden, and remission of geriatric depression. Neuropsychopharmacology 2004; 29:2278-2284
3. Potter GG, Kittinger JD, Wagner HR, et al: Prefrontal neuropsy-chological predictors of treatment remission in late-life depression. Neuropsychopharmacology 2004; 29:2266-2271
4. Sneed JR, Roose SP, Keilp JG, et al: Response inhibition predicts poor antidepressant treatment response in very old depressed patients. Am J Geriatr Psychiatry 2007; 15:553-563
5. Story TJ, Potter GG, Attix DK, et al: Neurocognitive correlates of response to treatment in late-life depression. Am J Geriatr Psychiatry 2008; 16:752-759
6. Kalayam B, Alexopoulos GS: Prefrontal dysfunction and treatment response in geriatric depression. Arch Gen Psychiatry 1999; 56: 713-718 (Pubitemid 29357732)
7. Alexopoulos GS, Meyers BS, Young RC, et al: Executive dysfunction and long-term outcomes of geriatric depression. Arch Gen Psychiatry 2000; 57:285-290
8. Butters MA, Bhalla RK, Mulsant BH, et al: Executive functioning, illness course, and relapse/recurrence in continuation and main tenance treatment of late-life depression: is there a relationship? Am J Geriatr Psychiatry 2004; 12:387-394
9. Lezak MD: Neuropsychological Assessment. NY, Oxford University Press, 1976, pp 549, xvii
10. Benton AL: Contributions to Neuropsychological Assessment: A Clinical Manual. 2nd Ed. NY, Oxford University Press, 1994, pp 159
11. Elderkin-Thompson V, Hellemann G, Pham D, et al: Prefrontal brain morphology and executive function in healthy and depressed elderly. Int J Geriatr Psychiatry 2009; 24:459-468
12. Lecrubier Y: How do you define remission? Acta Psychiatr Scand Suppl 2002:7-11
13. Alexopoulos GS, Kiosses DN, Heo M, et al: Executive dysfunction and the course of geriatric depression. Biol Psychiatry 2005; 58:204-210
14. Gold BT, Balota DA, Kirchhoff BA, et al: Common and dissociable activation patterns associated with controlled semantic and phonological processing: evidence from FMRI adaptation. Cereb Cortex 2005; 15:1438-1450
15. Gold BT, Balota DA, Jones SJ, et al: Dissociation of automatic and strategic lexical-semantics: functional magnetic resonance imaging evidence for differing roles of multiple frontotemporal regions. J Neurosci 2006; 26:6523-6532
16. Simpson S, Baldwin RC, Jackson A, et al: Is subcortical disease associated with a poor response to antidepressants? Neurological, neuropsychological and neuroradiological findings in late-life depression. Psychol Med 1998; 28:1015-1026
17. Alexopoulos GS, Kiosses DN, Choi SJ, et al: Frontal white matter microstructure and treatment response of late-life depression: a preliminary study. Am J Psychiatry 2002; 159: 1929-1932
18. Alexopoulos GS, Murphy CF, Gunning-Dixon FM, et al: Mi-crostructural white matter abnormalities and remission of geriatric depression. Am J Psychiatry 2008; 165:238-244
19. Davies RR, Graham KS, Xuereb JH, et al: The human perirhi-nal cortex and semantic memory. Eur J Neurosci 2004; 20: 2441-2446
20. Folstein MF, Folstein SE, McHugh PR: "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12:189-198
21. Lingjaerde O, Ahlfors UG, Bech P, et al: The UKU side effect rating scale. A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients. Acta Psychiatr Scand Suppl 1987; 334: 1-100
22. Alexopoulos GS, Meyers BS, Young RC, et al: The course of geriatric depression with "reversible dementia": a controlled study. Am J Psychiatry 1993; 150:1693-1699
23. Troyer AK, Moscovitch M, Winocur G: Clustering and switching as two components of verbal fluency: evidence from younger and older healthy adults. Neuropsychology 1997; 11: 138-146
24. Lezak MD: Neuropsychological Assessment. 3rd Ed. NY, Oxford University Press, 1995, pp 1026, xviii
25. Brandt J, Benedict R: Hopkins Verbal Learning Test-Revised. Professional Manual. Lutz FL, Psychological Assessment Resources, Inc., 2001
26. Rhodes MG: Age-related differences in performance on the Wisconsin card sorting test: a meta-analytic review. Psychol Aging 2004; 19:482-494
27. Murphy CF, Gunning-Dixon FM, Hoptman MJ, et al: White-matter integrity predicts stroop performance in patients with geriatric depression. Biol Psychiatry 2007; 61:1007-1010
28. Aizenstein HJ, Butters MA, Wu M, et al: Altered functioning of the executive control circuit in late-life depression: episodic and persistent phenomena. Am J Geriatr Psychiatry 2009;17:30-42
29. Elderkin-Thompson V, Mintz J, Haroon E, et al: Executive dysfunction and memory in older patients with major and minor depression. Arch Clin Neuropsychol 2007; 22:261-270
30. Elderkin-Thompson V, Kumar A, Mintz J, et al: Executive dysfunction and visuospatial ability among depressed elders in a community setting. Arch Clin Neuropsychol 2004; 19:597-611
31. Pyykkonen B, Hunter SJ, Lacy M, et al: An analysis of the unique contribution of executive functioning, language and verbal memory to verbal fluency tasks using hierarchical regression, in Lifes-pan Neuropsychology: Transdisciplinary Issues and New Horizons. 37th Annual Meeting of the International Neuropsycholog-ical Society, Atlanta, GA, February 12, 2009
32. Binder JR, Desai RH, Graves WW, et al: Where is the semantic system? A critical review and meta-analysis of 120 functional neu-roimaging studies. Cereb Cortex 2009; 19:2767-2796
33. Potter GG, Blackwell AD, McQuoid DR, et al: Prefrontal white matter lesions and prefrontal task impersistence in depressed and nondepressed elders. Neuropsychopharmacology 2007; 32:2135-2142