Effect of substitution on the antimycobacterial activity of 2-(substituted benzyl)sulfanyl benzimidazoles, benzoxazoles, and benzothiazoles - A quantitative structure-activity relationship study

Chemical and Pharmaceutical Bulletin

Volumn 59, Issue 2, 2011, Pages 179-184

  Pytela, Oldřich ^a   Klimešová, Věra ^b  

^a UNIVERSITY OF PARDUBICE   (Czech Republic)

^b Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

2 benzylsulfanyl derivative; Antimycobacterial activity; Benzimidazole; Benzothiazole; Benzoxazole; Quantitative structure activity relationship

Indexed keywords

ANTIMYCOBACTERIAL AGENT; BENZIMIDAZOLE DERIVATIVE; BENZOTHIAZOLE; BENZOXAZOLE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; DRUG STRUCTURE; LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM AVIUM; MYCOBACTERIUM KANSASII; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLARIZATION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANTI-BACTERIAL AGENTS; BENZIMIDAZOLES; BENZOTHIAZOLES; BENZOXAZOLES; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM AVIUM; MYCOBACTERIUM KANSASII; MYCOBACTERIUM TUBERCULOSIS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79551487826     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.59.179     Document Type: Article

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