Effect of donor-recipient age difference on graft function and survival in live-donor kidney transplantation

Nephrology Dialysis Transplantation

Volumn 26, Issue 2, 2011, Pages 702-708

  Ferrari, Paolo ^a,b   Lim, Wai ^b,c   Dent, Hannah ^d,e   McDonald, Stephen P ^d,f  

^a FREMANTLE HOSPITAL   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c SIR CHARLES GAIRDNER HOSPITAL   (Australia)

^d ANZDATA Registry   (Australia)

^e UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^f ROYAL ADELAIDE HOSPITAL   (Australia)

Author keywords

disparity; donor age; kidney transplantation; living donors; recipient outcome

Indexed keywords

ANTIMETABOLITE; AZATHIOPRINE; CREATININE; CYCLOSPORIN; MYCOPHENOLIC ACID; PREDNISOLONE; TACROLIMUS;

ADOLESCENT; ADULT; AGE DISTRIBUTION; ARTICLE; AUSTRALIA; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FEMALE; GRAFT FAILURE; GRAFT RECIPIENT; GRAFT SURVIVAL; HEALTH PROGRAM; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DONOR; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEW ZEALAND; PRIORITY JOURNAL;

ADULT; AGE FACTORS; FEMALE; GRAFT SURVIVAL; HUMANS; KIDNEY TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; REGISTRIES; SURVIVAL ANALYSIS;

EID: 79551479670     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfq383     Document Type: Article

References (24)

1. Terasaki PI, Cecka JM, Gjertson DWet al. High survival rates of kidney transplants from spousal and living unrelated donors. N Engl J Med 1995; 333: 333-336
2. Voiculescu A, Ivens K, Hetzel GR et al. Kidney transplantation from related and unrelated living donors in a single German centre. Nephrol Dial Transplant 2003; 18: 418-425
3. Simforoosh N, Basiri A, Fattahi MR et al. Living unrelated versus living related kidney transplantation: 20 years' experience with 2155 cases. Transplant Proc 2006; 38: 422-425
4. Iordanous Y, Seymour N, Young A et al. Recipient outcomes for expanded criteria living kidney donors: the disconnect between current evidence and practice. Am J Transplant 2009; 9: 1558-1573
5. Langle F, Sautner T, Grunberger T et al. Impact of donor age on graft function in living-related kidney transplantation. Transplant Proc 1992; 24: 2725-2727
6. Toma H, Tanabe K, Tokumoto T et al. Time-dependent risk factors influencing the long-term outcome in living renal allografts: donor age is a crucial risk factor for long-term graft survival more than 5 years after transplantation. Transplantation 2001; 72: 940-947
7. Gill JS, Gill J, Rose C et al. The older living kidney donor: part of the solution to the organ shortage. Transplantation 2006; 82: 1662-1666
8. Lunn M, McNeil D. Applying Cox regression to competing risks. Biometrics 1995; 51: 524-532
9. Terasaki PI, Gjertson DW, Cecka JM et al. Significance of the donor age effect on kidney transplants. Clin Transpl 1997; 11: 366-372
10. Collins MG, Chang SH, Russ GR et al. Outcomes of transplantation using kidneys from donors meeting expanded criteria in Australia and New Zealand, 1991 to 2005. Transplantation 2009; 87: 1201-1209
11. Kerr SR, Gillingham KJ, Johnson EM et al. Living donors >55 years: to use or not to use? Transplantation 1999; 67: 999-1004
12. Tanaka K, Kinukawa T, Matsuura O et al. The effect of donor age on living-related kidney transplantation. Transplant Proc 2000; 32: 1583-1584
13. Ivanovski N, Popov Z, Kolevski P et al. Use of advanced age donors in living renal transplantation-is it justified? Transplant Proc 2001; 33: 1227-1228
14. Hadjiyannakis EJ, Hadjidimitriou F, Drakopoulos S et al. Renal transplantation from older living donors. Transplant Proc 2001; 33: 906-908
15. Kumar A, Verma BS, Srivastava A et al. Long-term followup of elderly donors in a live related renal transplant program. J Urol 2000; 163: 1654-1658
16. Curschellas E, Landmann J, Durig M et al. Morphologic findings in "zero-hour" biopsies of renal transplants. Clin Nephrol 1991; 36: 215-222
17. Epstein M. Aging and the kidney. J Am Soc Nephrol 1996; 7: 1106-1122
18. Lim WH, Chang SH, Coates PT et al. Parental donors in live-donor kidney transplantation associated with increased rejection rates and reduced glomerular filtration rates. Transplantation 2007; 84: 972-980
19. Segev DL, Gentry SE, Warren DS et al. Kidney paired donation and optimizing the use of live donor organs. JAMA 2005; 293: 1883-1890
20. de Klerk M, Witvliet MD, Haase-Kromwijk BJ et al. Hurdles, barriers, and successes of a national living donor kidney exchange program. Transplantation 2008; 86: 1749-1753
21. Ferrari P, Woodroffe C, Christiansen FT. Paired kidney donations to expand the living donor pool: the Western Australian experience. Med J Aust 2009; 190: 700-703
22. Ferrari P, De Klerk M. Paired kidney donations to expand the living donor pool. J Nephrol 2009; 22: 699-707
23. Rowe JW, Andres R, Tobin JD et al. The effect of age on creatinine clearance in men: a cross-sectional and longitudinal study. J Gerontol 1976; 31: 155-163
24. Meier-Kriesche HU, Port FK, Ojo AO et al. Effect of waiting time on renal transplant outcome. Kidney Int 2000; 58: 1311-1317