Triacylglycerol deposition with group IVC phospholipase A2 expression in oleate- and linoleate-stimulated Huh-7 hepatocytes

Biological and Pharmaceutical Bulletin

Volumn 34, Issue 2, 2011, Pages 191-196

  Ishihara, Keiichi ^a   Tachibana, Kengo ^a   Kuroda, Asuka ^a   Terakawa, Ayano ^a   Baba, Shinsuke ^a   Kanai, Shiho ^a   Akiba, Satoshi ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Fatty liver; Free fatty acid; Hepatocellular triacylglycerol; Hepatocyte; Phospholipase A2

Indexed keywords

LINOLEIC ACID; MESSENGER RNA; METHYLARACHIDONYL FLUOROPHOSPHONATE; MUTANT PROTEIN; OLEIC ACID; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 GROUP IVA; PHOSPHOLIPASE A2 GROUP IVC; PHOSPHOLIPASE A2 GROUP VIA; PHOSPHOLIPASE A2 GROUP VIB; PHOSPHOLIPASE A2 INHIBITOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL STIMULATION; CELL STRAIN HUH 7; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIPID STORAGE; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; WILD TYPE;

FATTY ACIDS, NONESTERIFIED; FATTY LIVER; GROUP IV PHOSPHOLIPASES A2; HEPATOCYTES; HUMANS; LINOLEIC ACIDS; OLEIC ACIDS; RNA, MESSENGER; TRIGLYCERIDES;

EID: 79551476912     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.34.191     Document Type: Article

References (20)

1. Bradbury M. W., Am. J. Physiol. Gastrointest. Liver Physiol., 290, G194-G198 (2006).
2. Marchesini G., Bugianesi E., Forlani G., Cerrelli F., Lenzi M., Manini R., Natale S., Vanni E., Villanova N., Melchionda N., Rizzetto M., Hepatology, 37, 917-923 (2003).
3. Donnelly K. L., Smith C. I., Schwarzenberg S. J., Jessurun J., Boldt M. D., Parks E. J., J. Clin. Invest., 115, 1343-1351 (2005).
4. Tran K., Wang Y., DeLong C. J., Cui Z., Yao Z., J. Biol. Chem., 275, 25023-25030 (2000).
5. Schaloske R. H., Dennis E. A., Biochim. Biophys. Acta, 1761, 1246-1259 (2006).
6. Burke J. E., Dennis E. A., J. Lipid Res., 50, S237-S242 (2009).
7. Asai K., Hirabayashi T., Houjou T., Uozumi N., Taguchi R., Shimizu T., J. Biol. Chem., 278, 8809-8814 (2003).
8. Yamashita A., Kamata R., Kawagishi N., Nakanishi H., Suzuki H., Sugiura T., Waku K., J. Biochem. (Tokyo), 137, 557-567 (2005).
9. Tucker D. E., Stewart A., Nallan L., Bendale P., Ghomashchi F., Gelb M. H., Leslie C. C., J. Lipid Res., 46, 2122-2133 (2005).
10. Ii H., Oka M., Yamashita A., Waku K., Uozumi N., Shimizu T., Sato T., Akiba S., Biol. Pharm. Bull., 31, 6-12 (2008).
11. Ii H., Yokoyama N., Yoshida S., Tsutsumi K., Hatakeyama S., Sato T., Ishihara K., Akiba S., PLoS One, 4, e8089 (2009).
12. Stewart A., Ghosh M., Spencer D. M., Leslie C. C., J. Biol. Chem., 277, 29526-29536 (2002).
13. Ludwig J., Bovens S., Brauch C., Elfringhoff A. S., Lehr M., J. Med. Chem., 49, 2611-2620 (2006).
14. Jenkins C. M., Han X., Mancuso D. J., Gross R. W., J. Biol. Chem., 277, 32807-32814 (2002).
15. Murakami M., Masuda S., Kudo I., Biochem. J., 372, 695-702 (2003).
16. Pickard R. T., Strifler B. A., Kramer R. M., Sharp J. D., J. Biol. Chem., 274, 8823-8831 (1999).
17. Duan L., Gan H., Arm J., Remold H. G., J. Immunol., 166, 7469-7476 (2001).
18. Shi Y., Cheng D., Am. J. Physiol. Endocrinol. Metab., 297, E10-E18 (2009).
19. Lio Y. C., Reynolds L. J., Balsinde J., Dennis E. A., Biochim. Biophys. Acta, 1302, 55-60 (1996).
20. Yamashita A., Tanaka K., Kamata R., Kumazawa T., Suzuki N., Koga H., Waku K., Sugiura T., Biochim. Biophys. Acta, 1791, 1011-1022 (2009).