An H1-histamine receptor antagonist decreases serum interleukin-31 levels in patients with atopic dermatitis

British Journal of Dermatology

Volumn 164, Issue 2, 2011, Pages 455-456

  Otsuka, A ^a   Honda, T ^a   Doi, H ^a   Miyachi, Y ^a   Kabashima, Kenji ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EPINASTINE; INTERLEUKIN 31;

ADULT; ATOPIC DERMATITIS; BLOOD ANALYSIS; CLINICAL ARTICLE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; LETTER; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PRURITUS; VISUAL ANALOG SCALE;

ADULT; AGED; DERMATITIS, ATOPIC; DIBENZAZEPINES; FEMALE; HISTAMINE H1 ANTAGONISTS; HUMANS; IMIDAZOLES; INTERLEUKINS; MALE; MIDDLE AGED; PAIN MEASUREMENT; YOUNG ADULT;

EID: 79551473573     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2010.10083.x     Document Type: Letter

References (5)

1. Dillon SR, Sprecher C, Hammond A, et al. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol 2004; 5: 752-60.
2. Sonkoly E, Muller A, Lauerma AI, et al. IL-31: a new link between T cells and pruritus in atopic skin inflammation. J Allergy Clin Immunol 2006; 117: 411-17.
3. Raap U, Wichmann K, Bruder M, et al. Correlation of IL-31 serum levels with severity of atopic dermatitis. J Allergy Clin Immunol 2008; 122: 421-3.
4. Oshima KZ, Asano K, Kanai K, et al. Influence of epinastine hydrochloride, an H1-receptor antagonist, on the function of mite allergen-pulsed murine bone marrow-derived dendritic cells in vitro and in vivo. Mediators Inflamm 2009; 2009: 738038.
5. Gutzmer R, Mommert S, Gschwandtner M, et al. The histamine H4 receptor is functionally expressed on T(H)2 cells. J Allergy Clin Immunol 2009; 123: 619-25.