Does varicocele repair improve male infertility? An evidence-based perspective from a randomized, controlled trial

European Urology

Volumn 59, Issue 3, 2011, Pages 455-461

  Abdel Meguid, Taha A ^a,b   Al Sayyad, Ahmad ^a   Tayib, Abdulmalik ^a   Farsi, Hasan M ^a  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^b MINIA UNIVERSITY   (Egypt)

Author keywords

Evidence based infertility; Male infertility; Pregnancy; Subfertile men; Varicocele; Varicocele repair; Varicocelectomy

Indexed keywords

ADULT; ARTICLE; AZOOSPERMIA; EVIDENCE BASED PRACTICE; HUMAN; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; OUTCOME ASSESSMENT; PREGNANCY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SEMEN ANALYSIS; SPERMATOZOON MOTILITY; VARICOCELECTOMY;

ADULT; EVIDENCE-BASED MEDICINE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFERTILITY, MALE; MALE; MICROSURGERY; PREGNANCY; PREGNANCY RATE; SEMEN; VARICOCELE; WATCHFUL WAITING; YOUNG ADULT;

EID: 79551471964     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2010.12.008     Document Type: Article

References (28)

1. M. Cocuzza, M.A. Cocuzza, F.M.P. Bragais, and A. Agarwal The role of varicocele repair in the new era of assisted reproductive technology Clinics 63 2008 395 404
2. A. Agarwal, F. Deepinder, and M. Cocuzza Efficacy of varicocelectomy in improving semen parameters: new meta-analytical approach Urology 70 2007 532 538
3. J.L. Marmar, A. Agarwal, and S. Prabakaran Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis Fertil Steril 88 2007 639 646
4. V. Ficarra, M.A. Cerruto, and G. Liguori Treatment of varicocele in subfertile men: the Cochrane review - a contrary opinion Eur Urol 49 2006 258 263
5. I. Madgar, R. Weissenberg, B. Lunenfeld, A. Karasik, and B. Goldwasser Controlled trial of high spermatic vein ligation for varicocele in infertile men Fertil Steril 63 1995 120 124
6. T.B. Hargreave Varicocele: overview and commentary on the results of the World Health Organisation varicocele trial G.M.H. Waites, J. Frick, G.W.H. Baker, Current Advances in Andrology, Proceedings of the VIth International Congress of Andrology Salzburg, Austria. May 25-29, 1997 1997 Monduzzi Editore Bologna, Italy 31 44
7. J.L. Marmar, and Y. Kim Subinguinal microsurgical varicocelectomy: a technical critique and statistical analysis of semen and pregnancy data J Urol 152 1994 1127 1132
8. M. Goldstein, B.R. Gilbert, A.P. Dicker, J. Dwosh, and C. Gnecco Microsurgical inguinal varicocelectomy with delivery of the testis: an artery and lymphatic sparing technique J Urol 148 1992 1808 1811
9. S. Cayan, T.C. Kadioglu, A. Tefekli, A. Kadioglu, and S. Tellaloglu Comparison of results and complications of high ligation surgery and microsurgical high inguinal varicocelectomy in the treatment of varicocele Urology 55 2000 750 754
10. J. Sayfan, Y. Soffer, and R. Orda Varicocele treatment: prospective randomized trial of 3 methods J Urol 148 1992 1447 1449
11. J.L. Evers, and J.A. Collins Surgery or embolisation for varicocele in subfertile men Cochrane Database Syst Rev 2004 CD000479
12. J.L.H. Evers, and J.A. Collins Assessment of efficacy of varicocele repair for male subfertility: a systematic review Lancet 361 2003 1849 1852
13. A. Kamischke, and E. Nieschlag Varicocele treatment in the light of evidence based andrology Hum Reprod Update 7 2001 65 69
14. E. Nieschlag, L. Hertle, A. Fischedick, K. Abshagen, and H.M. Behre Update on treatment of varicocele: counselling as effective as occlusion of the vena spermatica Hum Reprod 13 1998 2147 2150
15. S. Nilsson, A. Edvinsson, and B. Nilsson Improvement of semen and pregnancy rate after ligation and division of the internal spermatic vein: fact or fiction? Br J Urol 51 1979 591 596
16. W. Krause, H.H. Muller, H. Schafer, and W. Weidner Does treatment of varicocele improve male fertility? Results of the "Deutsche Varikozelenstudie," a multicentre study of 14 collaborating centres Andrologia 34 2002 164 171
17. K.F. Schulz, D.G. Altman, D. Moher the CONSORT Group CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials BMJ 340 2010 c332
18. G. Novara, V. Ficarra, and W. Artibani Evidence-based medicine: the supporting pillar of trial registration Eur Urol 56 2009 956 958
19. S.A. Kidd, B. Eskenazi, and A.J. Wyrobek Effects of male age on semen quality and fertility: a review of the literature Fertil Steril 75 2001 237 248
20. E. De La Rochebrochard, and P. Thonneau Paternal age ≥40 years: an important risk factor for infertility Am J Obstet Gynecol 189 2003 901 905
21. A. Zini, J. Boman, K. Jarvi, and A. Baazeem Varicocelectomy for infertile couples with advanced paternal age Urology 72 2008 109 113
22. S.P. Robinson, L.J. Hampton, and H.P. Koo Treatment strategy for the adolescent varicocele Urol Clin North Am 37 2010 269 278
23. E. Tielemans, D. Heederik, A. Burdorf, D. Loomis, and D.F. Habbema Intraindividual variability and redundancy of semen parameters Epidemiol 8 1997 99 103
24. J. Auger, F. Eustache, and B. Ducot Intra- and inter-individual variability in human sperm concentration, motility and vitality assessment during a workshop involving ten laboratories Hum Reprod 15 2000 2360 2368
25. J.P. Bonde, E. Ernst, and T.K. Jensen Relation between semen quality and fertility: a population-based study of 430 first-pregnancy planners Lancet 352 1998 1172 1177
26. K.P. Nallella, R.K. Sharma, and N. Aziz Significance of sperm characteristics in the evaluation of male infertility Fertil Steril 85 2006 629 634
27. D.S. Guzick, J.W. Overstreet, and P. Factor-Litvak Sperm morphology, motility, and concentration in fertile and infertile men N Engl J Med 345 2001 1388 1393
28. I.H. Hirsch, T.A. Abdel-Meguid, and L.G. Gomella Postsurgical outcomes assessment following varicocele ligation: laparoscopic versus subinguinal approach Urology 51 1998 810 815