Involvement of α6/α3 neuronal nicotinic acetylcholine receptors in neuropsychiatric features of Dementia with Lewy bodies: [ 125I]-α-conotoxin MII binding in the thalamus and striatum

Neuroscience Letters

Volumn 372, Issue 3, 2004, Pages 220-225

  Ray, Melissa ^a   Bohr, Iwo ^a   McIntosh, J Michael ^b   Ballard, Clive ^a   McKeith, Ian ^a   Chalon, Sylvie ^d   Guilloteau, Denis ^d   Perry, Robert ^c   Perry, Elaine ^a   Court, J A ^a   Piggott, Margaret ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

^d UNIVERSITÉ DE TOURS   (France)

Author keywords

Dementia with Lewy bodies; Impaired consciousness; Neuronal nicotinic acetylcholine receptors; Striatum; Thalamus; Visual hallucinations

Indexed keywords

ALPHA CONOTOXIN MII; ALPHA3 NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR; ALPHA6 NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR; CONOTOXIN; IODINE 125; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG; ALPHA-CONOTOXIN MII; CARRIER PROTEIN; DOPAMINE; DOPAMINE TRANSPORTER; MEMBRANE PROTEIN; NERVE PROTEIN; NICOTINIC RECEPTOR ALPHA6; NICOTINIC RECEPTOR BLOCKING AGENT;

AGED; ARTICLE; AUTORADIOGRAPHY; BRAIN LEVEL; CAUDATE NUCLEUS; COGNITIVE DEFECT; CONSCIOUSNESS DISORDER; CONTROLLED STUDY; CORPUS STRIATUM; DEMENTIA; DEMENTIA WITH LEWY BODY; DOPAMINERGIC SYSTEM; FEMALE; HUMAN; HUMAN TISSUE; LEWY BODY; MALE; NEUROLOGIC DISEASE; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PUTAMEN; QUANTITATIVE ANALYSIS; RECEPTOR BINDING; THALAMUS; VISUAL HALLUCINATION; BRAIN; CONSCIOUSNESS; DIFFUSE LEWY BODY DISEASE; HALLUCINATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; SEXUAL DEVELOPMENT;

AGED; AGED, 80 AND OVER; AUTORADIOGRAPHY; BRAIN; CONOTOXINS; CONSCIOUSNESS; CORPUS STRIATUM; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; HALLUCINATIONS; HUMANS; LEWY BODY DISEASE; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; NICOTINIC ANTAGONISTS; RECEPTORS, NICOTINIC; SEX CHARACTERISTICS; THALAMUS;

EID: 7944235178     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.09.042     Document Type: Article

References (53)

1. L. Azam, H. Ursula, W. Winzer-Serhan, L. Chen, and F.M. Leslie Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs within midbrain dopaminergic neurons J. Comp. Neurol. 444 2002 260 274
2. C.G. Ballard, I.G. McKeith, D.G. Burn, R. Harrison, J.T. O'Brien, K. Lowery, M. Campbell, R.H. Perry, and P. Ince The UPDRS scale as a means of identifying extrapyramidal signs in patients suffering from dementia with Lewy bodies Acta Neuropathol. Scand. 96 1997 366 371
3. C.G. Ballard, M.A. Piggott, M. Johnson, N. Cairns, R.H. Perry, I.G. McKeith, E. Jaros, J.T. O'Brien, C. Holmes, and E. Perry Delusions associated with elevated muscarinic binding in dementia with Lewy bodies Ann. Neurol. 48 2000 868 876
4. C.G. Ballard, K. Saad, A. Patel, M. Gahir, M. Solis, B. Coope, and G.K. Wilcock The prevalence and phenomenology of psychotic symptoms in dementia sufferers Int. J. Geriatr. Psychiatr. 10 1995
5. R. Barber, A. Panikkar, and I.G. McKeith Dementia with Lewy bodies: diagnosis and management Int. J. Geriatr. Psychiatr. 16 2001 S12 S18
6. S. Blond, D. Caparros-Lefebvre, F. Parker, R. Assaker, H. Petit, J.-D. Guieu, and J.-L. Christiaens Control of tremor and involuntary movement disorders by chronic stereotactic stimulation of the ventral intermediate thalamic nucleus J. Neurosurg. 77 1992 62 68
7. J.E. Bogen On the neurophysiology of consciousness: I. An overview Conscious. Cogn. 4 1995 52 62
8. A. Burns, R. Jacoby, R. Levy, Psychiatric phenomena in Alzheimer's disease. II: disorders of perception, Br. J. Psychiatr., 157 (1990) 76-81, 92-4.
9. E.J. Byrne, G. Lennox, J. Lowe, and R.B. Godwin-Austen Diffuse Lewy body disease: clinical features in 15 cases J. Neurol. Neurosurg. Psychiatr. 52 1989 709 717
10. N. Champtiaux, C. Gotti, M. Cordero-Erasquin, D.J. David, C. Przybylski, C. Lena, F. Clementi, M. Moretti, F.M. Rossi, N. Le Novere, J.M. McIntosh, A.M. Gardier, and J.-P. Changeux Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice J. Neurosci. 23 2003 7820 7829
11. P.B.S. Clarke, and A. Pert Autoradiographic evidence for nicotinic receptors on nigralstriatal and mesolimbic dopaminergic neurons Brain Res. 348 1985 355 358
12. J.A. Court, C.G. Ballard, M.A. Piggott, M. Johnson, J.T. O'Brien, C. Holmes, N. Cairns, P. Lantos, R.H. Perry, E. Jaros, and E.K. Perry Visual hallucinations are associated with lower abungarotoxin binding in dementia with Lewy bodies Pharmacol. Biochem. Behavior. 70 2001 571 579
13. J.A. Court, M.A. Piggott, S. Lloyd, N. Cookson, C.G. Ballard, I.G. McKeith, R.H. Perry, and E.K. Perry Nicotine binding in human striatum: elevation in schizophrenia and reductions in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease and in relation to neuroleptic medication Neuroscience 98 2000 79 87
14. J. Court, D. Spurden, S. Lloyd, I. McKeith, C. Ballard, N. Cairns, R. Kerwin, R. Perry, and E. Perry Neuronal nicotinic receptors in Dementia with Lewy Bodies and schizophrenia: α-bungarotoxin and nicotine binding in the thalamus J. Neurochem. 73 1999 1590 1597
15. M.E. Dewey, J.R.M. Copeland, A. Lobo, P. Saz, and S.L. Dia Computerised diagnosis from a standardised history schedule: a preliminary communication about the organic section of the HAS-AGECAT system Int. J. Geriatr. Psychiatr. 7 1992 443 446
16. A. Freeman, B. Ciliax, R. Bakay, J. Daley, R.D. Miller, G. Keating, A.I. Levey, and D.B. Rye Nigrostriatal collaterals to thalamus degenerate in parkinsonian animal models Ann. Neurol. 50 2001 321 329
17. A. Graham, J.A. Court, C.M. Martin-Ruiz, E. Jaros, R. Perry, S.G. Volsen, S. Bose, N. Evans, P. Ince, A. Kuryatov, J. Lindstrom, C. Gotti, and E.K. Perry Immunohistochemical localization of nicotinic acetylcholine receptor subunits in human cerebellum Neuroscience 113 2002 493 507
18. H.J. Groenewegen, and H.W. Berendse The specificity of the 'nonspecific' midline and intralaminar thalamic nuclei Trends Neurosci. 17 1994 52 58
19. H. Hall, C. Halldin, D. Guilloteau, S. Chalon, P. Emond, J.-C. Besnard, L. Farde, and G. Sedvall Visualization of the dopamine transporter in the human brain postmortem with the new selective ligand [125I]PE2I Neuroimage 9 1999 108 116
20. E.G. Jones The Thalamus 1985 Plenum Press
21. S. Jones, S. Sudweeks, and J.L. Yakel Nicotinic receptors in the brain: correlating physiology with function Trends Neurosci. 22 1999 555 561
22. 3H] dopamine release from rat striatal synaptosomes and slices J. Neurochem. 1998 70
23. T.W. Kjaer, C. Bertelsen, P. Piccini, D. Brooks, J. Alving, and H.C. Lou Increased dopamine tone during meditation-induced change of consciousness Cogn. Brain Res. 13 2002
24. J.M. Kulak, J.M. McIntosh, and M. Quik Loss of nicotinic receptors in monkey striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment is due to a decline in α-conotoxin MII sites Mol. Pharmacol. 61 2002 230 238
25. J.M. Kulak, H.N. Nguyen, B.M. Olivera, and J.M. McIntosh α-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes J. Neurosci. 17 1997 5263 5270
26. P.J. Langlais, L.J. Thal, L.A. Hansen, D. Galasko, M. Alford, and E. Masliah Neurotransmitters in basal ganglia and cortex of Alzheimer's didease with and without Lewy bodies Neurology 43 1993 1927 1934
27. N. Le Novere, and J.-P. Changeux Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells J. Mol. Evol. 40 1995 155 172
28. J.K. Mai, J. Assheuer, and G. Paxinos Atlas of the Human Brain 1997 Academic Press
29. C.M. Martin-Ruiz, S. Lawrence, M.A. Piggott, A. Kuryatov, J. Lindstrom, C. Gotti, M.R. Cookson, R.H. Perry, E. Jaros, E.K. Perry, and J.A. Court Nicotinic receptors in the putamen of patients with dementia with Lewy bodies and Parkinson's disease: relation to changes in α-synuclein expression Neurosci. Lett. 335 2002 134 138
30. I.G. McKeith Dementia with Lewy bodies Br. J. Psychiatr. 180 2002 144 147
31. I.G. McKeith, D. Galasko, K. Kosaka, E.K. Perry, D.W. Dickson, L.A. Hansen, D.P. Salmon, J. Lowe, S.S. Mirra, E.J. Byrne, G. Lennox, N.P. Quinn, J.A. Edwardson, P.G. Ince, C. Bergeron, A. Burns, B.L. Miller, S. Lovestone, D. Collerton, E.N.H. Jansen, C.G. Ballard, R.A.I. de Vos, G.K. Wilcock, K.A. Jellinger, and R.H. Perry Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop Neurology 47 1996 1113 1124
32. E.K. Perry, E.F. Marshall, R.H. Perry, D. Irving, C.J. Smith, G. Blessed, A.F. Fairbairn, and Cholinergic Dopaminergic activities in senile dementia of Lewy body type Alzheimer Dis. Assoc. Disord. 4 1990 87 95
33. E.K. Perry, I.G. McKeith, P. Thompson, E.F. Marshall, J. Kerwin, S. Jabeen, J.A. Edwardson, P. Ince, G. Blessed, and D. Irving Topography, extent, and clinical relevance of neurochemical deficits in dementia of Lewy body type, Parkinson's disease, and Alzheimer's disease Ann. NY Acad. Sci. 640 1991 197 202
34. E.K. Perry, C. Morris, J.A. Court, A. Cheng, A.F. Fairbairn, I.G. McKeith, D. Irving, A. Brown, and R.H. Perry Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: possible index of early neuropathology Neuroscience 64 1995 385 395
35. E.K. Perry, and R.H. Perry Acetylcholine and hallucinations: disease-related compared to drug-induced alterations in human consciousness Brain Cogn. 28 1995 240 258
36. E.K. Perry, C.J. Smith, J.A. Court, and R.H. Perry Cholinergic nicotinic and muscarinic receptors in dementia of Alzheimer, Parkinson and Lewy body types J. Neural. Transm. Parkinsons Dis. Dementia Sec. 2 1990 149 158
37. E.K. Perry, M. Walker, J. Grace, and R.H. Perry Acetylcholine in mind: a neurotransmitter correlate of consciousness Trends Neurosci. 22 1999 273 280
38. R.H. Perry, D. Irving, G. Blessed, A. Fairbairn, and E.K. Perry Senile dementia of Lewy body type. A clinically and neuropathologically distinct form of Lewy body dementia in the elderly J. Neurol. Sci. 95 1990 119 139
39. M.A. Piggott, E.F. Marshall, N. Thomas, S. Lloyd, J.A. Court, E. Jaros, D.G. Burn, M. Johnson, R.H. Perry, I.G. McKeith, C.G. Ballard, and E.K. Perry Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution Brain 122 1999 1449 1468
40. 125I]-A-85380 Neuropsychopharmacology 29 2004 108 116
41. M. Quik, L. Bordia, L. Forno, and J.M. McIntosh Loss of α-conotoxinMII- and A85380-sensitive nicotinic receptors in Parkinson's disease striatum J. Neurochem. 88 2004 668 679
42. M. Quik, Y. Polonskaya, J.M. Kulak, and J.M. McIntosh Vulnerability of 125I-α-conotoxin MII binding sites to nigrostriatal damage in monkey J. Neurosci. 21 2001 5500 5594
43. M. Quik, J.D. Sum, P. Whiteaker, S.E. McCallum, M.J. Marks, J.L. Musachio, J.M. McIntosh, A.C. Collins, and S.R. Grady Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice Mol. Pharmacol. 63 2003 1169 1179
44. E. Rausell, and E.G. Jones Chemically distinct compartments of the thalamic VPM nucleus in monkeys relay principal and spinal trigeminal pathways to different layers of the somatosensory cortex J. Neurosci. 11 1991 226 237
45. R.T. Reid, M.N. Sabbagh, J. Corey-Bloom, P. Tiraboschi, and L.J. Thal Nicotinic receptors in dementia with Lewy bodies: comparisons with Alzheimer's disease Neurobiol. Aging 21 2000 741 746
46. M. Roth, E. Tym, C.Q. Mountjoy, F.A. Huppert, H. Hendrie, S. Verma, and R. Goddard CAMDEX. A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia Br. J. Psychiatr. 1986 149
47. F. Rubboli, J.A. Court, C. Sala, C. Morris, B. Chini, E. Perry, and F. Clementi Distribution of nicotinic receptors in the human hippocampus and thalamus Eur. J. Neurosci. 6 1994 1596 1604
48. M. Samochocki, A. Hoffle, A. Fehrenbacher, R. Jostock, J. Ludwig, C. Christner, M. Radina, M. Zerlin, C. Ullmer, E.F.R. Pereira, H. Lubbert, E.X. Albuquerque, and A. Maelicke Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors J. Pharmacol. Exp. Ther. 305 2003 1024 1036
49. M. Walker, G. Ayre, J.L. Cummings, K. Wesnes, I.G. McKeith, J.T. O'Brien, and C.G. Ballard The clinician assesment of fluctuation and the one day fluctuation assessment scale: two methods to assess fluctuating confusion in dementia Br. J. Psychiatr. 177 2000 252 256
50. M.P. Walker, G. Ayre, J.L. Cummings, K. Wesnes, I.G. McKeith, J.T. O'Brien, and C.G. Ballard Quantifying fluctuation in dementia with Lewy bodies, Alzheimer's disease, and vascular dementia Neurology 54 2000 1616 1625
51. 125I-α-conotoxin MII identifies a novel nicotinic acetylcholine receptor population in mouse brain Mol. Pharmacol. 57 2000 913 925
52. M. Yoshida The neuronal mechanism underlying parkinsonism and dyskinesia, and differential roles of the putamen and caudate nucleus Adv. Neurol. 60 1993 71 77
53. M. Zoli, M. Moretti, A. Zanardi, J.M. McIntosh, F. Clementi, and C. Gotti Identification of the nicotinic receptor subtypes expressed on dopaminergic terminals in the rat striatum J. Neurosci. 22 2002 8785 8789