Novel functional imaging for tissue oxygen concentration and redox status

Journal of Nutrition

Volumn 134, Issue 11, 2004, Pages

  Mitchell, James B ^a   Yamada, Kenichi ^a   Devasahayam, Nallathamby ^a   Cook, John A ^a   Subramanian, Sankaran ^a   Krishna, Murali C ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Electron paramagnetic resonance imaging; Functional imaging; Hypoxia; Redox imaging

Indexed keywords

OXYGEN;

CONFERENCE PAPER; DIAGNOSTIC IMAGING; ELECTRON SPIN RESONANCE; HUMAN; HYPOXIA; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; OXYGEN ELECTRODE; OXYGEN TISSUE LEVEL; OXYGENATION;

EID: 7944233054     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/134.11.3210s     Document Type: Conference Paper

References (6)

1. Hockel, M., Schlenger, K., Aral, B., Mitze, M., Schaffer, U. & Vaupel, P. (1996) Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 56: 4509-4515.
2. Golman, K., Leunbach, I., Ardenkjaer-Larsen, J. H., Ehnholm, G. J., Wistrand, L. G., Petersson, J. S., Jarvi, A. & Vahasalo, S. (1998) Overhauser-enhanced MR imaging (OMRI) Acta Radiol. 39: 10-17.
3. Krishna, M. C., English, S., Yamada, K., Yoo, J., Murugesan, R., Devasahayam, N., Cook, J. A., Golman, K., Ardenkjaer-Larsen, J. H., et al. (2002) Overhauser enhanced magnetic resonance imaging for tumor oximetry: coregistration of tumor anatomy and tissue oxygen concentration. Proc. Natl. Acad. Sci. 99: 2216-2221.
4. Kuppusamy, P., Li, H., Ilangovan, G., Cardounci, A. J., Zweier, J. L., Yamada, K., Krishna, M. C. & Mitchell, J. B. (2002) Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels. Cancer Res. 62: 307-312.
5. Yamada, K. I., Kuppusamy, P., English, S., Yoo, J., Irie, A., Subramanian, S., Mitchell, J. B. & Krishna, M. C. (2002) Feasibility and assessment of non-invasive in vivo redox status using electron paramagnetic resonance imaging. Acta Radiol. 43: 433-440.
6. Ilangovan, G., Li, H., Zweier, J. L., Krishna, M. C., Mitchell, J. B. & Kuppasamy, P. (2002) In vivo measurement of regional oxygenation and imaging of redox status in RIF-1 murine tumor: effect of carbogen-breathing. Magn. Reson. Med. 48: 723-730.