Constitutive activation of the thyroid-stimulating hormone receptor (TSHR) by mutating Ile691 in the cytoplasmic tail segment

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Liu, Zheng ^a,b   Fan, Feiyue ^a   Xiao, Xiangjun ^c   Sun, Yuanming ^a  

^a INSTITUTE OF RADIATION MEDICINE   (China)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INOSITOL PHOSPHATE; ISOLEUCINE; THYROTROPIN RECEPTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL LEVEL; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; GENE LOCATION; HUMAN; NONHUMAN; NUCLEOTIDE METABOLISM; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; WILD TYPE; GENETICS; HYPERTHYROIDISM; METABOLISM; MUTATION; PROTEIN CONFORMATION; RARE DISEASE;

CYCLIC AMP; CYTOPLASM; GERM-LINE MUTATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; HYPERTHYROIDISM; INOSITOL PHOSPHATES; ISOLEUCINE; MUTATION; PROTEIN CONFORMATION; RARE DISEASES; RECEPTORS, THYROTROPIN;

EID: 79251627927     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016335     Document Type: Article

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