Targeting hypoxia-induced inflammation

Anesthesiology

Volumn 114, Issue 2, 2011, Pages 239-242

  Eltzschig, Holger K ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; DOPAMINE; LIDOCAINE; SPHINGOSINE KINASE 1; TETRACAINE; TOLL LIKE RECEPTOR 4;

ACUTE KIDNEY FAILURE; ACUTE LUNG INJURY; ATELECTASIS; CREATININE BLOOD LEVEL; EDITORIAL; GENE EXPRESSION; GLOMERULUS FILTRATION RATE; GRAFT FAILURE; HEART MUSCLE ISCHEMIA; HYPOXIA; INFLAMMATION; INTESTINE ISCHEMIA; LIVER FAILURE; LIVER TRANSPLANTATION; LUNG EDEMA; MORBIDITY; MORTALITY; MOUNTAINEERING; MULTIPLE ORGAN FAILURE; NEPHRITIS; NONHUMAN; PERIOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROKE;

EID: 79251625729     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e3182070c66     Document Type: Editorial

References (35)

1. Kim M, Park SW, Kim M, D'Agati VD, Lee HT: Isoflurane activates intestinal sphingosine kinase to protect against renal ischemia-reperfusion induced liver and intestine injury. ANESTHESIOLOGY 2011; 114:363-73
2. Colgan SP, Taylor CT: Hypoxia: An alarm signal during intestinal inflammation. Nat Rev Gastroenterol Hepatol 2010; 7:281-7
3. Taylor CT: Interdependent roles for hypoxia inducible factor and nuclear factor-kappaB in hypoxic inflammation. J Physiol 2008; 586:4055-9
4. Grocott MP, Martin DS, Levett DZ, McMorrow R, Windsor J, Montgomery HE: Arterial blood gases and oxygen content in climbers on Mount Everest. N Engl J Med 2009; 360:140-9
5. Hartmann G, Tschop M, Fischer R, Bidlingmaier C, Riepl R, Tschop K, Hautmann H, Endres S, Toepfer M: High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein. Cytokine 2000; 12:246-52
6. Rosenberger P, Schwab JM, Mirakaj V, Masekowsky E, Mager A, Morote-Garcia JC, Unertl K, Eltzschig HK: Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia. Nat Immunol 2009; 10:195-202
7. Kruger B, Krick S, Dhillon N, Lerner SM, Ames S, Bromberg JS, Lin M, Walsh L, Vella J, Fischereder M, Kramer BK, Colvin RB, Heeger PS, Murphy BT, Schroppel B: Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc Natl Acad Sci USA 2009; 106:3390-5
8. Thabut G, Mal H, Cerrina J, Dartevelle P, Dromer C, Velly JF, Stern M, Loirat P, Leseche G, Bertocchi M, Mornex JF, Haloun A, Despins P, Pison C, Blin D, Reynaud-Gaubert M: Graft ischemic time and outcome of lung transplantation: A multicenter analysis. Am J Respir Crit Care Med 2005; 171: 786-91
9. Eckle T, Grenz A, Laucher S, Eltzschig HK: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice. J Clin Invest 2008; 118: 3301-15
10. Schingnitz U, Hartmann K, Macmanus CF, Eckle T, Zug S, Colgan SP, Eltzschig HK: Signaling through the A2B adenosine receptor dampens endotoxin-induced acute lung injury. J Immunol 2010; 184:5271-9
11. Karhausen J, Furuta GT, Tomaszewski JE, Johnson RS, Colgan SP, Haase VH: Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. J Clin Invest 2004; 114: 1098-106
12. Eltzschig HK: Adenosine: An old drug newly discovered. ANESTHESIOLOGY 2009; 111:904-15
13. Sadovnikoff N, Gelman S: Perioperative renal protection. Curr Opin Anaesthesiol 1999; 12:337-41
14. Abuelo JG: Normotensive ischemic acute renal failure. N Engl J Med 2007; 357:797-805
15. Schrier RW, Wang W: Acute renal failure and sepsis. N Engl J Med 2004; 351:159-69
16. Jones DR, Lee HT: Perioperative renal protection. Best Pract Res Clin Anaesthesiol 2008; 22:193-208
17. Yalavarthy R, Edelstein CL, Teitelbaum I: Acute renal failure and chronic kidney disease following liver transplantation. Hemodial Int 2007; 11(suppl 3):S7-12
18. Parikh CR, Jani A, Mishra J, Ma Q, Kelly C, Barasch J, Edelstein CL, Devarajan P: Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation. Am J Transplant 2006; 6:1639-45
19. Jones DR, Lee HT: Protecting the kidney during critical illness. Curr Opin Anaesthesiol 2007; 20:106-12
20. Kim M, Kim N, D'Agati VD, Emala CW Sr, Lee HT: Isoflurane mediates protection from renal ischemia-reperfusion injury via sphingosine kinase and sphingosine-1-phosphate-dependent pathways. Am J Physiol Renal Physiol 2007; 293: F1827-35
21. Song JH, Kim M, Park SW, Chen SW, Pitson SM, Lee HT: Isoflurane via TGF-beta1 release increases caveolae formation and organizes sphingosine kinase signaling in renal proximal tubules. Am J Physiol Renal Physiol 2010; 298: F1041-50
22. Birukov KG, Jacobson JR, Flores AA, Ye SQ, Birukova AA, Verin AD, Garcia JG: Magnitude-dependent regulation of pulmonary endothelial cell barrier function by cyclic stretch. Am J Physiol Lung Cell Mol Physiol 2003; 285:L785-97
23. Lee HT, Krichevsky IE, Xu H, Ota-Setlik A, D'Agati VD, Emala CW: Local anesthetics worsen renal function after ischemiareperfusion injury in rats. Am J Physiol Renal Physiol 2004; 286:F111-9
24. Morote-Garcia JC, Rosenberger P, Kuhlicke J, Eltzschig HK: HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak. Blood 2008; 111:5571-80
25. Morote-Garcia JC, Rosenberger P, Nivillac NM, Coe IR, Eltzschig HK: Hypoxia-inducible factor-dependent repression of equilibrative nucleoside transporter 2 attenuates mucosal inflammation during intestinal hypoxia. Gastroenterology 2009; 136:607-18
26. Eltzschig HK, Ibla JC, Furuta GT, Leonard MO, Jacobson KA, Enjyoji K, Robson SC, Colgan SP: Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: Role of ectonucleotidases and adenosine A2B receptors. J Exp Med 2003; 198:783-96
27. Grenz A, Zhang H, Eckle T, Mittelbronn M, Wehrmann M, Kohle C, Kloor D, Thompson LF, Osswald H, Eltzschig HK: Protective role of ecto-5-nucleotidase (CD73) in renal ischemia. J Am Soc Nephrol 2007; 18:833-45
28. Grenz A, Zhang H, Hermes M, Eckle T, Klingel K, Huang DY, Muller CE, Robson SC, Osswald H, Eltzschig HK: Contribu- tion of E-NTPDase1 (CD39) to renal protection from ischemia- reperfusion injury. FASEB J 2007; 21:2863-73
29. Lee HT, Xu H, Nasr SH, Schnermann J, Emala CW: A1 adenosine receptor knockout mice exhibit increased renal injury following ischemia and reperfusion. Am J Physiol Renal Physiol 2004; 286:F298 -306
30. Gallos G, Ruyle TD, Emala CW, Lee HT: A1 adenosine receptor knockout mice exhibit increased mortality, renal dysfunction, and hepatic injury in murine septic peritonitis. Am J Physiol Renal Physiol 2005; 289:F369 -76
31. Kim M, Chen SW, Park SW, D'Agati VD, Yang J, Lee HT: Kidney-specific reconstitution of the A1 adenosine receptor in A1 adenosine receptor knockout mice reduces renal ischemia- reperfusion injury. Kidney Int 2009; 75:809-23
32. Park SW, Chen SW, Kim M, Brown KM, D'Agati VD, Lee HT: Protection against acute kidney injury via A(1) adenosine receptor-mediated Akt activation reduces liver injury after liver ischemia and reperfusion in mice. J Pharmacol Exp Ther 2010; 333:736-47
33. Grenz A, Osswald H, Eckle T, Yang D, Zhang H, Tran ZV, Klingel K, Ravid K, Eltzschig HK: The reno-vascular A2B adenosine receptor protects the kidney from ischemia. PLoS Med 2008; 5:e137
34. Bagshaw SM, Delaney A, Haase M, Ghali WA, Bellomo R: Loop diuretics in the management of acute renal failure: A systematic review and meta-analysis. Crit Care Resusc 2007; 9:60-8
35. Bove T, Landoni G, Calabro MG, Aletti G, Marino G, Cerchierini E, Crescenzi G, Zangrillo A: Renoprotective action of fenoldopam in high-risk patients undergoing cardiac surgery: A prospective, double-blind, randomized clinical trial. Circulation 2005; 111:3230-5