High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein

Cytokine

Volumn 12, Issue 3, 2000, Pages 246-252

  Hartmann, G ^b   Tschop M ^a   Fischer, R ^c   Bidlingmaier, C ^b   Riepl, R ^c   Tschop K ^b   Hautmann, H ^a   Endres, S ^b   Toepfer, M ^c  

^a UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c NONE

Author keywords

C reactive protein; Cytokines; High altitude; Hypoxia; Interleukin 1 receptor antagonist; Interleukin 6

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6;

ADULT; ALTITUDE DISEASE; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; LUNG EDEMA; MALE; PRIORITY JOURNAL;

EID: 0033939095     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1999.0533     Document Type: Article

References (38)

1. Ghezzi P, Dinarello CA, Bianchi M, Rosandich ME, Repine JE, White CW. Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells. Cytokine. 3:1991;189-194.
2. Hempel SL, Monick MM, Hunninghake GW. Effect of hypoxia on release of IL-1 and TNF by human alveolar macrophages. Am J Respir Cell Mol Biol. 14:1996;170-176.
3. Scannell G. Leukocyte responses to hypoxic/ischemic conditions. New Horiz. 4:1996;179-183.
4. VanOtteren GM, Standiford TJ, Kunkel SL, Danforth JM, Strieter RM. Alterations of ambient oxygen tension modulate the expression of tumor necrosis factor and macrophage inflammatory protein-1 alpha from murine alveolar macrophages. Am J Respir Cell Mol Biol. 13:1995;399-409.
5. Shreeniwas R, Koga S, Karakurum M, Pinsky D, Kaiser E, Brett J, Wolitzky BA, Norton C, Plocinski J, Benjamin W, Burns DK, Goldstein A, Stern D. Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface. J Clin Invest. 90:1992;2333-2339.
6. Yan SF, Ogawa S, Stern DM, Pinsky DJ. Hypoxia-induced modulation of endothelial cell properties: regulation of barrier function and expression of interleukin-6. Kidney Int. 51:1997;419-425.
7. Ala Y, Palluy O, Favero J, Bonne C, Modat G, Dornand J. Hypoxia/reoxygenation stimulates endothelial cells to promote interleukin-1 and interleukin-6 production. Effects of free radical scavengers. Agents Actions. 37:1992;134-139.
8. Ginis I, Mentzer SJ, Faller DV. Oxygen tension regulates neutrophil adhesion to human endothelial cells via an LFA-1-dependent mechanism. J Cell Physiol. 157:1993;569-578.
9. Karakurum M, Shreeniwas R, Chen J, Pinsky D, Yan SD, Anderson M, Sunouchi K, Major J, Hamilton T, Kuwabara K. Hypoxic induction of interleukin-8 gene expression in human endothelial cells. J Clin Invest. 93:1994;1564-1570.
10. Hamilton AJ, Cymmerman A, Black PM. High altitude cerebral edema. Neurosurgery. 19:1986;841-849.
11. Bärtsch P. High altitude pulmonary edema. Respiration. 64:1997;435-443.
12. Scherrer U, Vollenweider L, Delabays A, Savcic M, Eichenberger U, Kleger GR, Fikrle A, Ballmer PE, Nicod P, Bärtsch P. Inhaled nitric oxide for high-altitude pulmonary edema. N Engl J Med. 334:1996;624-629.
13. Goerre S, Wenk M, Bärtsch P, Luscher TF, Niroomand F, Hohenhaus E, Oelz O, Reinhart WH. Endothelin-1 in pulmonary hypertension associated with high-altitude exposure. Circulation. 91:1995;359-364.
14. Droma Y, Ge RL, Tanaka M, Koizumi T, Hanaoka M, Miyahara T, Yamaguchi S, Okada K, Yoshikawa S, Fujimoto K, Matsuzawa Y, Kubo K, Kobayashi T, Sekiguchi M. Acute hypoxic pulmonary vascular response does not accompany plasma endothelin-1 elevation in subjects susceptible to high altitude pulmonary edema. Intern Med. 35:1996;257-260.
15. Schoene RB, Swenson ER, Pizzo CJ, Hackett PH, Roach RC, Mills WJ Jr, Henderson WR Jr, Martin TR. The lung at high altitude: bronchoalveolar lavage in acute mountain sickness and pulmonary edema. J Appl Physiol. 64:1988;2605-2613.
16. Kleger GR, Bärtsch P, Vock P, Heilig B, Roberts Ln, Ballmer PE. Evidence against an increase in capillary permeability in subjects exposed to high altitude. J Appl Physiol. 81:1996;1917-1923.
17. Hansen JM, Olsen NV, Feldt-Rasmussen B, Kanstrup IL, Dechaux M, Dubray C, Richalet JP. Albuminuria and overall capillary permeability of albumin in acute altitude hypoxia. J Appl Physiol. 76:1994;1922-1927.
18. Tschöp M, Strasburger CJ, Hartmann G, Biollaz J, Bärtsch P. Elevated leptin levels at high altitude are associated with loss of appetite. Lancet. 352:1998;1119-1120.
19. Toepfer M, Hartmann G, Schlosshauer M, Hautmann H, Tschöp M, Fischer R, Huber RM. Adrenomedullin: a player at high altitude? Chest. 113:1998;1428.
20. Bartsch P. High altitude pulmonary edema. Respiration. 64:1997;435-443.
21. Kubo K, Hanaoka M, Yamaguchi S, Hayano T, Hayasaka M, Koizumi T, Fujimoto K, Kobayashi T, Honda T. Cytokines in bronchoalveolar lavage fluid in patients with high altitude pulmonary oedema at moderate altitude in Japan. Thorax. 51:1996;739-742.
22. Kaminsky DA, Jones K, Schoene RB, Voelkel NF. Urinary leukotriene E4 levels in high-altitude pulmonary edema. A possible role for inflammation. Chest. 110:1996;939-945.
23. Carpenter TC, Reeves JT, Durmowicz AG. Viral respiratory infection increases susceptibility of young rats to hypoxia-induced pulmonary edema. J Appl Physiol. 84:1998;1048-1054.
24. Ziesche R, Petkov V, Williams J, Zakeri SM, Mosgoller W, Knofler M, Block LH. Lipopolysaccharide and interleukin 1 augment the effects of hypoxia and inflammation in human pulmonary arterial tissue. Proc Natl Acad Sci U S A. 93:1996;12 478-12 483.
25. Liu SF, Dewar A, Crawley DE, Barnes PJ, Evans TW. Effect of tumor necrosis factor on hypoxic pulmonary vasoconstriction. J Appl Physiol. 72:1992;1044-1049.
26. Swenson ER, MacDonald A, Vatheuer M, Maks C, Treadwell A, Allen R, Schoene RB. Acute mountain sickness is not altered by a high carbohydrate diet nor associated with elevated circulating cytokines. Aviat Space Environ Med. 68:1997;499-503.
27. Adamik B, Zimecki M, Wlaszczyk A, Kubler A. Immunological status of septic and trauma patients: High tumor necrosis factor alpha serum levels in septic and trauma patients are not responsible for increased mortality; a prognostic value of serum interleukin 6. Arch Immunol Ther Exp. 45:1997;169-175.
28. Herrmann JL, Blanchard H, Brunengo P, Lagrange PH. TNF alpha, IL-1 beta and IL-6 plasma levels in neutropenic patients after onset of fever and correlation with the C-reactive protein (CRP) kinetic values. Infection. 22:1994;309-315.
29. Arend WP, Malyak M, Guthridge CJ, Gabay C. Interleukin-1 receptor antagonist: role in biology. Annu Rev Immunol. 16:1998;27-55.
30. Eigler A, Sinha B, Hartmann G, Endres S. Taming TNF: strategies to restrain this proinflammatory cytokine. Immunol Today. 18:1997;487-492.
31. Szaflarski J, Burtrum D, Silverstein FS. Cerebral hypoxia-ischemia stimulates cytokine gene expression in perinatal rats. Stroke. 26:1995;1093-1100.
32. Hori O, Matsumoto M, Kuwabara K, Maeda Y, Ueda H, Ohtsuki T, Kinoshita T, Ogawa S, Stern DM, Kamada T. Exposure of astrocytes to hypoxia/reoxygenation enhances expression of glucose-regulated protein 78 facilitating astrocyte release of the neuroprotective cytokine interleukin 6. J Neurochem. 66:1996;973-979.
33. Matsuo N, Ogawa S, Imai Y, Takagi T, Tohyama M, Stern D, Wanaka A. Cloning of a novel RNA binding polypeptide (RA301) induced by hypoxia/reoxygenation. J Biol Chem. 270:1995;28 216-28 222.
34. Yamauchi TK, Ihara Y, Ogata A, Yoshizaki K, Azuma J, Kishimoto T. Hypoxic stress induces cardiac myocyte-derived interleukin-6. Circulation. 91:1995;1520-1524.
35. Klokker M, Kharazmi A, Galbo H, Bygbjerg I, Pedersen BK. Influence of in vivo hypobaric hypoxia on function of lymphocytes, neutrocytes, natural killer cells, and cytokines. J Appl Physiol. 74:1993;1100-1106.
36. Fandrey J. Hypoxia-inducible gene expression. Respir Physiol. 101:1995;1-10.
37. Klausen T, Olsen NV, Poulsen TD, Richalet JP, Pedersen BK. Hypoxemia increases serum interleukin-6 in humans. Eur J Appl Physiol. 76:1997;480-482.
38. Bärtsch P, Mueller A, Hofstetter D, Maggiorini M, Vock P, Oelz O. AMS and HAPE scoring in the Alps. Sutton JR, Houston CS, Coates G. Hypoxia and Molecular Medicine. 1993;265-271 Queen City Printers, Burlington.