High level of soluble HLA-G in amniotic fluid is correlated with congenital transmission of Toxoplasma gondii

Clinical Immunology

Volumn 138, Issue 2, 2011, Pages 129-134

  Robert Gangneux, Florence ^a,b   Gangneux, Jean Pierre ^a,b   Vu, Nicolas ^a,b   Jaillard, Sylvie ^a   Guiguen, Claude ^a   Amiot, Laurence ^a,b  

^a RENNES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Amniotic fluid; Congenital toxoplasmosis; HLA G; Immunity; Infection; SHLA G; Toxoplasma gondii

Indexed keywords

GAMMA INTERFERON; HLA G ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; PYRIMETHAMINE; SPIRAMYCIN; SULFADIAZINE; SULFADOXINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AMNION FLUID LEVEL; ANTIGEN EXPRESSION; ANTIMICROBIAL THERAPY; ARTICLE; CONGENITAL TOXOPLASMOSIS; CONTROLLED STUDY; DRUG SUBSTITUTION; FEMALE; FETUS; FETUS WASTAGE; HUMAN; HUMAN TISSUE; IMMUNOMODULATION; MAJOR CLINICAL STUDY; PARASITE TRANSMISSION; PLACENTAL TRANSFER; PREGNANT WOMAN; PRIMARY INFECTION; PRIORITY JOURNAL; TOXOPLASMA GONDII; VERTICAL TRANSMISSION;

AMNIOTIC FLUID; BIOLOGICAL MARKERS; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; INFANT; INFANT, NEWBORN; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; INTERFERON-GAMMA; INTERLEUKINS; MALE; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; RETROSPECTIVE STUDIES; TOXOPLASMA; TOXOPLASMOSIS, CONGENITAL; TROPHOBLASTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79251597891     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2010.12.004     Document Type: Article

References (39)

1. Pazmany L., Mandelboim O., Vales-Gomez M., Davis D.M., Reyburn H.T., Strominger J.L. Protection from natural killer cell-mediated lysis by HLA-G expression on target cells. Science 1996, 274:792-795.
2. Park G.M., Lee S., Park B., Kim E., Shin J., Cho K., Ahn K. Soluble HLA-G generated by proteolytic shedding inhibits NK-mediated cell lysis. Biochem Biophys Res Commun 2004, 313:606-611.
3. Kapasi K., Albert S.E., Yie S., Zavazava N., Librach C.L. HLA-G has a concentration-dependent effect on the generation of an allo-CTL response. Immunology 2000, 101:191-200.
4. Hunt J.S., Petroff M.G., McIntire R.H., Ober C. HLA-G and immune tolerance in pregnancy. FASEB J 2005, 19:681-693.
5. Ober C., Aldrich C.L. HLA-G polymorphisms: neutral evolution or novel function?. J Reprod Immunol 1997, 36:1-21.
6. Kirszenbaum M., Moreau P., Gluckman E., Dausset J., Carosella E. An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes. Proc Natl Acad Sci U S A 1994, 91:4209-4213.
7. Le Bouteiller P., Legrand-Abravanel F., Solier C. Soluble HLA-G1 at the materno-foetal interface-a review. Placenta 2003, 24(Suppl A):S10-S15.
8. Pace J.L., Morales P.J., Phillips T.A., Hunt J.S. Analysis of the soluble isoforms of HLA-G mRNAs and proteins. Methods Mol Med 2006, 122:181-203.
9. Rebmann V., LeMaoult J., Rouas-Freiss N., Carosella E.D., Grosse-Wilde H. Quantification and identification of soluble HLA-G isoforms. Tissue Antigens 2007, 69(Suppl 1):143-149.
10. Huang J., Burke P., Yang Y., Seiss K., Beamon J., Cung T., Toth I., Pereyra F., Lichterfeld M., Yu X.G. Soluble HLA-G inhibits myeloid dendritic cell function in HIV-1 infection by interactions with ILT4. J Virol 2010.
11. Donaghy L., Gros F., Amiot L., Mary C., Maillard A., Guiguen C., Gangneux J.P. Elevated levels of soluble non-classical major histocompatibility class I molecule human leucocyte antigen (HLA)-G in the blood of HIV-infected patients with or without visceral leishmaniasis. Clin Exp Immunol 2007, 147:236-240.
12. Pangault C., Le Tulzo Y., Minjolle S., Le Page E., Sebti Y., Guilloux V., Fauchet R., Amiot L. HLA-G expression in Guillain-Barre syndrome is associated with primary infection with cytomegalovirus. Viral Immunol 2004, 17:123-125.
13. Abbasi M., Kowalewska-Grochowska K., Bahar M.A., Kilani R.T., Winkler-Lowen B., Guilbert L.J. Infection of placental trophoblasts by Toxoplasma gondii. J Infect Dis 2003, 188:608-616.
14. Yap G.S., Sher A. Cell-mediated immunity to Toxoplasma gondii: initiation, regulation and effector function. Immunobiology 1999, 201:240-247.
15. Hunter C.A., Subauste C.S., Remington J.S. The role of cytokines in toxoplasmosis. Biotherapy 1994, 7:237-247.
16. Denkers E.Y., Gazzinelli R.T. Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection. Clin Microbiol Rev 1998, 11:569-588.
17. Entrican G. Immune regulation during pregnancy and host-pathogen interactions in infectious abortion. J Comp Pathol 2002, 126:79-94.
18. Kieffer F., Wallon M., Garcia P., Thulliez P., Peyron F., Franck J. Risk factors for retinochoroiditis during the first 2years of life in infants with treated congenital toxoplasmosis. Pediatr Infect Dis J 2008, 27:27-32.
19. Thiebaut R., Leproust S., Chene G., Gilbert R. Effectiveness of prenatal treatment for congenital toxoplasmosis: a meta-analysis of individual patients' data. Lancet 2007, 369:115-122.
20. McLeod R., Kieffer F., Sautter M., Hosten T., Pelloux H. Why prevent, diagnose and treat congenital toxoplasmosis?. Mem Inst Oswaldo Cruz 2009, 104:320-344.
21. Robert-Gangneux F., Gavinet M.F., Ancelle T., Raymond J., Tourte-Schaefer C., Dupouy-Camet J. Value of prenatal diagnosis and early postnatal diagnosis of congenital toxoplasmosis: retrospective study of 110 cases. J Clin Microbiol 1999, 37:2893-2898.
22. Romand S., Chosson M., Franck J., Wallon M., Kieffer F., Kaiser K., Dumon H., Peyron F., Thulliez P., Picot S. Usefulness of quantitative polymerase chain reaction in amniotic fluid as early prognostic marker of fetal infection with Toxoplasma gondii. Am J Obstet Gynecol 2004, 190:797-802.
23. Robert-Gangneux F., Dupretz P., Yvenou C., Quinio D., Poulain P., Guiguen C., Gangneux J.P. Clinical relevance of placenta examination for the diagnosis of congenital toxoplasmosis. Pediatr Infect Dis J 2010, 29:33-38.
24. Sebti Y., Le Friec G., Pangault C., Gros F., Drenou B., Guilloux V., Bernard M., Lamy T., Fauchet R., Amiot L. Soluble HLA-G molecules are increased in lymphoproliferative disorders. Hum Immunol 2003, 64:1093-1101.
25. Rebmann V., Lemaoult J., Rouas-Freiss N., Carosella E.D., Grosse-Wilde H. Report of the wet workshop for quantification of soluble HLA-G in Essen, 2004. Hum Immunol 2005, 66:853-863.
26. Yoon B.H., Romero R., Moon J.B., Shim S.S., Kim M., Kim G., Jun J.K. Clinical significance of intra-amniotic inflammation in patients with preterm labor and intact membranes. Am J Obstet Gynecol 2001, 185:1130-1136.
27. Jongert E., Lemiere A., Van Ginderachter J., De Craeye S., Huygen K., D'Souza S. Functional characterization of in vivo effector CD4(+) and CD8(+) T cell responses in acute Toxoplasmosis: an interplay of IFN-gamma and cytolytic T cells. Vaccine 2010, 28:2556-2564.
28. Senegas A., Villard O., Neuville A., Marcellin L., Pfaff A.W., Steinmetz T., Mousli M., Klein J.P., Candolfi E. Toxoplasma gondii-induced foetal resorption in mice involves interferon-gamma-induced apoptosis and spiral artery dilation at the maternofoetal interface. Int J Parasitol 2009, 39:481-487.
29. Pfaff A.W., Abou-Bacar A., Letscher-Bru V., Villard O., Senegas A., Mousli M., Candolfi E. Cellular and molecular physiopathology of congenital toxoplasmosis: the dual role of IFN-gamma. Parasitology 2007, 134:1895-1902.
30. Rebmann V., Pfeiffer K., Passler M., Ferrone S., Maier S., Weiss E., Grosse-Wilde H. Detection of soluble HLA-G molecules in plasma and amniotic fluid. Tissue Antigens 1999, 53:14-22.
31. Hammer A., Hutter H., Blaschitz A., Mahnert W., Hartmann M., Uchanska-Ziegler B., Ziegler A., Dohr G. Amnion epithelial cells, in contrast to trophoblast cells, express all classical HLA class I molecules together with HLA-G. Am J Reprod Immunol 1997, 37:161-171.
32. Jun Y., Kim E., Jin M., Sung H.C., Han H., Geraghty D.E., Ahn K. Human cytomegalovirus gene products US3 and US6 down-regulate trophoblast class I MHC molecules. J Immunol 2000, 164:805-811.
33. Thouvenin M., Candolfi E., Villard O., Klein J.P., Kien T. Immune response in a murine model of congenital toxoplasmosis: increased susceptibility of pregnant mice and transplacental passage of Toxoplasma gondii are type 2-dependent. Parassitologia 1997, 39:279-283.
34. Emmer P.M., Steegers E.A., van Lierop M.J., Loke Y.W., van der Meer A., Joosten I. Levels of soluble HLA-G in amniotic fluid are related to the sex of the offspring. Eur J Immunogenet 2003, 30:163-164.
35. Kusanovic J.P., Romero R., Jodicke C., Mazaki-Tovi S., Vaisbuch E., Erez O., Mittal P., Gotsch F., Chaiworapongsa T., Edwin S.S., Pacora P., Hassan S.S. Amniotic fluid soluble human leukocyte antigen-G in term and preterm parturition, and intra-amniotic infection/inflammation. J Matern Fetal Neonatal Med 2009, 22:1151-1166.
36. Kupferminc M.J., Peaceman A.M., Wigton T.R., Rehnberg K.A., Socol M.L. Tumor necrosis factor-alpha is elevated in plasma and amniotic fluid of patients with severe preeclampsia. Am J Obstet Gynecol 1994, 170:1752-1757. discussion 1757-1759.
37. Yie S.M., Li L.H., Li Y.M., Librach C. HLA-G protein concentrations in maternal serum and placental tissue are decreased in preeclampsia. Am J Obstet Gynecol 2004, 191:525-529.
38. Hackmon R., Koifman A., Hyodo H., Glickman H., Sheiner E., Geraghty D.E. Reduced third-trimester levels of soluble human leukocyte antigen G protein in severe preeclampsia. Am J Obstet Gynecol 2007, 197:e251-e255.
39. Mazzucchelli I., Avanzini M.A., Ciardelli L., Pagani S., Greco R., Belloni C., Castellazzi A., Marconi M., Rondini G., Polatti F. Human amniotic fluid cells are able to produce IL-6 and IL-8. Am J Reprod Immunol 2004, 51:198-203.