Synthesis of (2S)-isopropyl-5-alkynylpyrimidin-2-ones: Precursors of β-aminoacids

Tetrahedron Letters

Volumn 52, Issue 9, 2011, Pages 1014-1019

  Stefani, Hélio A ^a   Amaral, Monica F Z J ^a   Juaristi, Eusebio ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Aminoacids; 5 Iodopyrimidinone; Alkynyltrifluoroborates; Cross coupling reaction; Suzuki Miyaura

Indexed keywords

BETA AMINO ACID; ISOPROPYL 5 ALKYNYLPYRIMIDIN 2 ONE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CROSS COUPLING REACTION; SUZUKI REACTION; SYNTHESIS;

EID: 79251597607     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.12.087     Document Type: Article

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21. 3) δ (ppm): 168.2; 162.1; 140.7; 132.4; 131.9; 131.6 (2C); 129.0 (2C); 128.6; 128.4 (2C); 128.2 (2C); 122.7; 101.3; 92.4; 82.1; 69.4; 33.0; 18.3; 17.5. MS: m/z (%): 344 (4, M+); 239 (5); 274 (5); 207 (5); 105 (100); 77 (50); 71 (37); 43 (61).