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Volumn 10, Issue 1, 2011, Pages 8-13

Understanding Dose Titration: Overactive Bladder Treatment With Fesoterodine as an Example

Author keywords

Dose response; Fesoterodine; Muscarinic antagonists; Overactive bladder; Pharmacodynamic; Pharmacokinetic

Indexed keywords

FESOTERODINE; PLACEBO;

EID: 79251597131     PISSN: 15699056     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eursup.2011.01.004     Document Type: Review
Times cited : (14)

References (34)
  • 1
    • 33746883214 scopus 로고    scopus 로고
    • Assessment of treatment outcomes in patients with overactive bladder: importance of objective and subjective measures
    • Abrams P., Artibani W., Gajewski J.B., Hussain I. Assessment of treatment outcomes in patients with overactive bladder: importance of objective and subjective measures. Urology 2006, 68:17-28.
    • (2006) Urology , vol.68 , pp. 17-28
    • Abrams, P.1    Artibani, W.2    Gajewski, J.B.3    Hussain, I.4
  • 2
    • 47949098266 scopus 로고    scopus 로고
    • The effects of antimuscarinic treatments in overactive bladder: an update of a systematic review and meta-analysis
    • Chapple C.R., Khullar V., Gabriel Z., Muston D., Bitoun C.E., Weinstein D. The effects of antimuscarinic treatments in overactive bladder: an update of a systematic review and meta-analysis. Eur Urol 2008, 54:543-562.
    • (2008) Eur Urol , vol.54 , pp. 543-562
    • Chapple, C.R.1    Khullar, V.2    Gabriel, Z.3    Muston, D.4    Bitoun, C.E.5    Weinstein, D.6
  • 3
    • 39549119348 scopus 로고    scopus 로고
    • Physiological and pathological regulation of the autonomic control of urinary bladder contractility
    • Michel M.C., Barendrecht M.M. Physiological and pathological regulation of the autonomic control of urinary bladder contractility. Pharmacol Ther 2008, 117:297-312.
    • (2008) Pharmacol Ther , vol.117 , pp. 297-312
    • Michel, M.C.1    Barendrecht, M.M.2
  • 4
    • 2342569763 scopus 로고    scopus 로고
    • Novel polymorphisms influencing transcription of the human CHRM2 gene in airway smooth muscle
    • Fenech A.G., Billington C.K., Swan C., et al. Novel polymorphisms influencing transcription of the human CHRM2 gene in airway smooth muscle. Am J Respir Cell Mol Biol 2004, 30:678-686.
    • (2004) Am J Respir Cell Mol Biol , vol.30 , pp. 678-686
    • Fenech, A.G.1    Billington, C.K.2    Swan, C.3
  • 5
    • 33644776510 scopus 로고    scopus 로고
    • Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study
    • Ancelin M.L., Artero S., Portet F., Dupuy A.M., Touchon J., Ritchie K. Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study. BMJ 2006, 332:455-459.
    • (2006) BMJ , vol.332 , pp. 455-459
    • Ancelin, M.L.1    Artero, S.2    Portet, F.3    Dupuy, A.M.4    Touchon, J.5    Ritchie, K.6
  • 6
    • 77249148434 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of tamsulosin in its modified-release and oral controlled absorption system formulations
    • Franco-Salinas G., de la Rosette J.J., Michel M.C. Pharmacokinetics and pharmacodynamics of tamsulosin in its modified-release and oral controlled absorption system formulations. Clin Pharmacokinet 2010, 49:177-188.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 177-188
    • Franco-Salinas, G.1    de la Rosette, J.J.2    Michel, M.C.3
  • 7
    • 0031895694 scopus 로고    scopus 로고
    • Pharmacokinetics and plasma protein binding of tamsulosin hydrochloride in rats, dogs, and humans
    • Matsushima H., Kamimura H., Soeishi Y., Watanabe T., Higuchi S., Tsunoo M. Pharmacokinetics and plasma protein binding of tamsulosin hydrochloride in rats, dogs, and humans. Drug Metab Dispos 1998, 26:240-245.
    • (1998) Drug Metab Dispos , vol.26 , pp. 240-245
    • Matsushima, H.1    Kamimura, H.2    Soeishi, Y.3    Watanabe, T.4    Higuchi, S.5    Tsunoo, M.6
  • 8
    • 70449335342 scopus 로고    scopus 로고
    • Assessment of central nervous system access of a new antimuscarinic drug, fesoterodine
    • Kay G., Malhotra B., Michel M. Assessment of central nervous system access of a new antimuscarinic drug, fesoterodine. J Urol 2010, 181:84.
    • (2010) J Urol , vol.181 , pp. 84
    • Kay, G.1    Malhotra, B.2    Michel, M.3
  • 9
    • 0742286803 scopus 로고    scopus 로고
    • Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry
    • Zanger U.M., Raimundo S., Eichelbaum M. Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch Pharmacol 2004, 369:23-37.
    • (2004) Naunyn Schmiedebergs Arch Pharmacol , vol.369 , pp. 23-37
    • Zanger, U.M.1    Raimundo, S.2    Eichelbaum, M.3
  • 10
    • 33645515459 scopus 로고    scopus 로고
    • The clinical pharmacokinetics of darifenacin
    • Skerjanec A. The clinical pharmacokinetics of darifenacin. Clin Pharmacokinet 2006, 45:325-350.
    • (2006) Clin Pharmacokinet , vol.45 , pp. 325-350
    • Skerjanec, A.1
  • 11
    • 0344944933 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of drugs used to treat urge incontinence
    • Guay D.R. Clinical pharmacokinetics of drugs used to treat urge incontinence. Clin Pharmacokinet 2003, 42:1243-1285.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 1243-1285
    • Guay, D.R.1
  • 12
    • 58149267871 scopus 로고    scopus 로고
    • Muscarinic receptor antagonists for overactive bladder treatment: does one fit all?
    • Witte L.P., Mulder W.M., de la Rosette J.J., Michel M.C. Muscarinic receptor antagonists for overactive bladder treatment: does one fit all?. Curr Opin Urol 2009, 19:13-19.
    • (2009) Curr Opin Urol , vol.19 , pp. 13-19
    • Witte, L.P.1    Mulder, W.M.2    de la Rosette, J.J.3    Michel, M.C.4
  • 13
    • 77950801791 scopus 로고    scopus 로고
    • Patient-reported reasons for discontinuing overactive bladder medication
    • Benner J.S., Nichol M.B., Rovner E.S., et al. Patient-reported reasons for discontinuing overactive bladder medication. BJU Int 2009, 105:1276-1282.
    • (2009) BJU Int , vol.105 , pp. 1276-1282
    • Benner, J.S.1    Nichol, M.B.2    Rovner, E.S.3
  • 15
    • 33745602006 scopus 로고    scopus 로고
    • Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder
    • Abrams P., Andersson K.E., Buccafusco J.J., et al. Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder. Br J Pharmacol 2006, 148:565-578.
    • (2006) Br J Pharmacol , vol.148 , pp. 565-578
    • Abrams, P.1    Andersson, K.E.2    Buccafusco, J.J.3
  • 16
    • 22544461052 scopus 로고    scopus 로고
    • Clinical pharmacology of antihypertensive therapy
    • Taylor A.A., Pool J.L. Clinical pharmacology of antihypertensive therapy. Semin Nephrol 2005, 25:215-226.
    • (2005) Semin Nephrol , vol.25 , pp. 215-226
    • Taylor, A.A.1    Pool, J.L.2
  • 17
    • 59949103451 scopus 로고    scopus 로고
    • Evidence why paroxetine dose escalation is not effective in major depressive disorder: a randomized controlled trial with assessment of serotonin transporter occupancy
    • Ruhe H.G., Booij J., v Weert H.C., et al. Evidence why paroxetine dose escalation is not effective in major depressive disorder: a randomized controlled trial with assessment of serotonin transporter occupancy. Neuropsychopharmacology 2009, 34:999-1010.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 999-1010
    • Ruhe, H.G.1    Booij, J.2    v Weert, H.C.3
  • 18
    • 70450270826 scopus 로고    scopus 로고
    • The design and development of fesoterodine as a prodrug of 5-hydroxymethyl tolterodine (5-HMT), the active metabolite of tolterodine
    • Malhotra B., Gandelman K., Sachse R., Wood N., Michel M.C. The design and development of fesoterodine as a prodrug of 5-hydroxymethyl tolterodine (5-HMT), the active metabolite of tolterodine. Curr Med Chem 2009, 16:4481-4489.
    • (2009) Curr Med Chem , vol.16 , pp. 4481-4489
    • Malhotra, B.1    Gandelman, K.2    Sachse, R.3    Wood, N.4    Michel, M.C.5
  • 20
    • 48049117725 scopus 로고    scopus 로고
    • Fesoterodine: a novel muscarinic receptor antagonist for the treatment of overactive bladder syndrome
    • Michel M.C. Fesoterodine: a novel muscarinic receptor antagonist for the treatment of overactive bladder syndrome. Expert Opin Pharmacother 2008, 9:1787-1796.
    • (2008) Expert Opin Pharmacother , vol.9 , pp. 1787-1796
    • Michel, M.C.1
  • 23
    • 67649979920 scopus 로고    scopus 로고
    • Influence of food on the pharmacokinetic profile of fesoterodine
    • Malhotra B., Sachse R., Wood N. Influence of food on the pharmacokinetic profile of fesoterodine. Int J Clin Pharmacol Ther 2009, 47:384-390.
    • (2009) Int J Clin Pharmacol Ther , vol.47 , pp. 384-390
    • Malhotra, B.1    Sachse, R.2    Wood, N.3
  • 24
    • 70349908417 scopus 로고    scopus 로고
    • Influence of age, gender, and race on pharmacokinetics, pharmacodynamics, and safety of fesoterodine
    • Malhotra B.K., Wood N., Sachse R. Influence of age, gender, and race on pharmacokinetics, pharmacodynamics, and safety of fesoterodine. Int J Clin Pharmacol Ther 2009, 47:570-578.
    • (2009) Int J Clin Pharmacol Ther , vol.47 , pp. 570-578
    • Malhotra, B.K.1    Wood, N.2    Sachse, R.3
  • 26
    • 63849202904 scopus 로고    scopus 로고
    • Assessment of the effects of renal impairment on the pharmacokinetic profile of fesoterodine
    • Malhotra B., Gandelman K., Sachse R., Wood N. Assessment of the effects of renal impairment on the pharmacokinetic profile of fesoterodine. J Clin Pharmacol 2009, 49:477-482.
    • (2009) J Clin Pharmacol , vol.49 , pp. 477-482
    • Malhotra, B.1    Gandelman, K.2    Sachse, R.3    Wood, N.4
  • 27
    • 79953820384 scopus 로고    scopus 로고
    • Effects of hepatic dysfunction on the single-dose pharmacokinetics of fesoterodine
    • In press. doi:10.1177/0091270010365547
    • deMey C, Maleva L, Kraslev Z, Sachse R, Wood N, Malhotra B. Effects of hepatic dysfunction on the single-dose pharmacokinetics of fesoterodine. J Clin Pharmacol. In press. doi:10.1177/0091270010365547.
    • J Clin Pharmacol
    • deMey, C.1    Maleva, L.2    Kraslev, Z.3    Sachse, R.4    Wood, N.5    Malhotra, B.6
  • 28
    • 42749089770 scopus 로고    scopus 로고
    • Fesoterodine dose response in subjects with overactive bladder syndrome
    • Khullar V., Rovner E.S., Dmochowski R., Nitti V., Wang J., Guan Z. Fesoterodine dose response in subjects with overactive bladder syndrome. Urology 2008, 71:839-843.
    • (2008) Urology , vol.71 , pp. 839-843
    • Khullar, V.1    Rovner, E.S.2    Dmochowski, R.3    Nitti, V.4    Wang, J.5    Guan, Z.6
  • 29
    • 27944440693 scopus 로고    scopus 로고
    • Fesoterodine a new effective and well-tolerated antimuscarinic for the treatment of urgency-frequency syndrome: results of a phase 2 controlled study
    • Chapple C., Vonkeman H., Hellmis E., Al-Shukri S., Arpo H. Fesoterodine a new effective and well-tolerated antimuscarinic for the treatment of urgency-frequency syndrome: results of a phase 2 controlled study. Neurourol Urodyn 2004, 23:598-599.
    • (2004) Neurourol Urodyn , vol.23 , pp. 598-599
    • Chapple, C.1    Vonkeman, H.2    Hellmis, E.3    Al-Shukri, S.4    Arpo, H.5
  • 30
    • 62249155166 scopus 로고    scopus 로고
    • Fesoterodine is an effective antimuscarinic for patients with overactive bladder (OAB): results of a phase 2 trial
    • Abstract presented at: Annual Meeting of the International Continence Society; 28 August-2 September; Montreal, Canada.
    • Nitti V, Viatrak M, Kreitman L, Lipsitz D. Fesoterodine is an effective antimuscarinic for patients with overactive bladder (OAB): results of a phase 2 trial. Abstract presented at: Annual Meeting of the International Continence Society; 28 August-2 September 2005; Montreal, Canada.
    • (2005)
    • Nitti, V.1    Viatrak, M.2    Kreitman, L.3    Lipsitz, D.4
  • 31
    • 62549133509 scopus 로고    scopus 로고
    • Effects of flexible-dose fesoterodine on overactive bladder symptoms and treatment satisfaction: an open-label study
    • Wyndaele J.J., Goldfischer E.R., Morrow J.D., et al. Effects of flexible-dose fesoterodine on overactive bladder symptoms and treatment satisfaction: an open-label study. Int J Clin Pract 2009, 63:560-567.
    • (2009) Int J Clin Pract , vol.63 , pp. 560-567
    • Wyndaele, J.J.1    Goldfischer, E.R.2    Morrow, J.D.3
  • 32
    • 72249114712 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of flexible-dose fesoterodine in subjects with overactive bladder
    • Dmochowski R.R., Peters K.M., Morrow J.D., et al. Randomized, double-blind, placebo-controlled trial of flexible-dose fesoterodine in subjects with overactive bladder. Urology 2010, 75:62-68.
    • (2010) Urology , vol.75 , pp. 62-68
    • Dmochowski, R.R.1    Peters, K.M.2    Morrow, J.D.3
  • 33
    • 77956471190 scopus 로고    scopus 로고
    • Dose escalation improves therapeutic outcome: post hoc analysis of data from a 12-week, multicentre, double-blind, parallel-group trial of trospium chloride in patients with urinary urge incontinence
    • Bodeker R.H., Madersbacher H., Neumeister C., Zellner M. Dose escalation improves therapeutic outcome: post hoc analysis of data from a 12-week, multicentre, double-blind, parallel-group trial of trospium chloride in patients with urinary urge incontinence. BMC Urol 2010, 10:15.
    • (2010) BMC Urol , vol.10 , pp. 15
    • Bodeker, R.H.1    Madersbacher, H.2    Neumeister, C.3    Zellner, M.4
  • 34
    • 77955683413 scopus 로고    scopus 로고
    • Modeling dose-response relationships of the effects of fesoterodine in patients with overactive bladder
    • Cardozo L., Khullar V., El-Tahtawy A., Guan Z., Malhotra B., Staskin D. Modeling dose-response relationships of the effects of fesoterodine in patients with overactive bladder. BMC Urol 2010, 10:14.
    • (2010) BMC Urol , vol.10 , pp. 14
    • Cardozo, L.1    Khullar, V.2    El-Tahtawy, A.3    Guan, Z.4    Malhotra, B.5    Staskin, D.6


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