Enzymatic Synthesis of Poly(α-ethyl β-aspartate) by Poly(ethylene glycol) Modified Poly(aspartate) Hydrolase-1

Macromolecular Bioscience

Volumn 11, Issue 2, 2011, Pages 187-191

  Hiraishi, Tomohiro ^a   Masuda, Eriko ^a,b   Miyamoto, Daisuke ^a,c   Kanayama, Naoki ^a,d   Abe, Hideki ^a,b   Maeda, Mizuo ^a  

^a RIKEN   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c Asahi Kasei Medical Co   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Biodegradable; Enzyme catalyzed polymerization; Modification; Poly(aspartate) hydrolase; Poly(ethylene glycol) modification; Water soluble polymers

Indexed keywords

AMIDE BOND; AMIDE LINKAGES; ASPARTATES; BIODEGRADABLE; CARBOXYL END GROUP; CARBOXYL TERMINUS; DISPERSIBILITIES; ENZYMATIC SYNTHESIS; ETHYL ESTERS; HYDROLASES; MALDI TOF MS; METABOLIC STABILITY; MODIFICATION; MODIFIED ENZYMES; NMR ANALYSIS; POLYCARBOXYLATES; SUBSTRATE SPECIFICITY; SYNTHESIZED POLYMERS; WATER-SOLUBLE POLYMERS;

AMIDES; BIODEGRADABLE POLYMERS; CATALYSIS; ENZYMES; ESTERS; ETHYLENE; ETHYLENE GLYCOL; ORGANIC SOLVENTS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERIZATION; SUBSTRATES;

POLYMERS;

ASPARTIC ACID DERIVATIVE; CARBOXYL GROUP; HYDROLASE; MACROGOL; ORGANIC SOLVENT; POLY(ALPHA ETHYL BETA ASPARTATE); POLY(ASPARTATE) HYDROLASE 1; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; DENSITY; DISPERSION; ENZYME MODIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

ELECTROPHORESIS, POLYACRYLAMIDE GEL; HYDROLASES; ISOASPARTIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR WEIGHT; PEPTIDES; POLYETHYLENE GLYCOLS; POLYMERIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

PEDOBACTER SP. KP-2;

EID: 79251549797     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201000199     Document Type: Article

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